KEGG   NETWORK: N01485
Entry
N01485                      Network                                
Name
Cohesin dissociation in prophase
Definition
SGO1+PP2A -| PLK1,AURKB,CDK1 -- STAG+CDCA5
  Expanded
151648+(5515,5516+5518,5519+5525,5526,5527,5528,5529) -| 5347,9212,983 -- 10274,10735+113130
Class
nt06512 Chromosome cohesion and segregation
Type
Reference
Gene
151648  SGO1; shugoshin 1
5515  PPP2CA; protein phosphatase 2 catalytic subunit alpha
5516  PPP2CB; protein phosphatase 2 catalytic subunit beta
5518  PPP2R1A; protein phosphatase 2 scaffold subunit Aalpha
5519  PPP2R1B; protein phosphatase 2 scaffold subunit Abeta
5525  PPP2R5A; protein phosphatase 2 regulatory subunit B'alpha
5526  PPP2R5B; protein phosphatase 2 regulatory subunit B'beta
5527  PPP2R5C; protein phosphatase 2 regulatory subunit B'gamma
5528  PPP2R5D; protein phosphatase 2 regulatory subunit B'delta
5529  PPP2R5E; protein phosphatase 2 regulatory subunit B'epsilon
5347  PLK1; polo like kinase 1
9212  AURKB; aurora kinase B
983  CDK1; cyclin dependent kinase 1
10274  STAG1; stromal antigen 1
10735  STAG2; stromal antigen 2
113130  CDCA5; cell division cycle associated 5
Reference
  Authors
Boavida A, Santos D, Mahtab M, Pisani FM
  Title
Functional Coupling between DNA Replication and Sister Chromatid Cohesion Establishment.
  Journal
Int J Mol Sci 22:2810 (2021)
DOI:10.3390/ijms22062810
Reference
  Authors
Losada A
  Title
Cohesin in cancer: chromosome segregation and beyond.
  Journal
Nat Rev Cancer 14:389-93 (2014)
DOI:10.1038/nrc3743
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