Homo sapiens (human): 10841
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Entry
10841 CDS
T01001
Symbol
FTCD, LCHC1
Name
(RefSeq) formimidoyltransferase cyclodeaminase
KO
K13990
glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase [EC:
2.1.2.5
4.3.1.4
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00340
Histidine metabolism
hsa00670
One carbon pool by folate
hsa01100
Metabolic pathways
Module
hsa_M00045
Histidine degradation, histidine => N-formiminoglutamate => glutamate
Network
nt06037
Histidine metabolism
Element
N01728
Histidine degradation 2
Disease
H01262
Formiminotransferase deficiency
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09105 Amino acid metabolism
00340 Histidine metabolism
10841 (FTCD)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
10841 (FTCD)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
hsa03036
]
10841 (FTCD)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hsa04147
]
10841 (FTCD)
Enzymes [BR:
hsa01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.5 glutamate formimidoyltransferase
10841 (FTCD)
4. Lyases
4.3 Carbon-nitrogen lyases
4.3.1 Ammonia-lyases
4.3.1.4 formimidoyltetrahydrofolate cyclodeaminase
10841 (FTCD)
Chromosome and associated proteins [BR:
hsa03036
]
Eukaryotic type
Centrosome formation proteins
Centriole proteins
10841 (FTCD)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
10841 (FTCD)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
FTCD_N
FTCD
FTCD_C
Motif
Other DBs
NCBI-GeneID:
10841
NCBI-ProteinID:
NP_006648
OMIM:
606806
HGNC:
3974
Ensembl:
ENSG00000160282
UniProt:
O95954
LinkDB
All DBs
Position
21:complement(46136262..46155579)
Genome browser
AA seq
541 aa
AA seq
DB search
MSQLVECVPNFSEGKNQEVIDAISGAITQTPGCVLLDVDAGPSTNRTVYTFVGPPECVVE
GALNAARVASRLIDMSRHQGEHPRMGALDVCPFIPVRGVSVDECVLCAQAFGQRLAEELD
VPVYLYGEAARMDSRRTLPAIRAGEYEALPKKLQQADWAPDFGPSSFVPSWGATATGARK
FLIAFNINLLGTKEQAHRIALNLREQGRGKDQPGRLKKVQGIGWYLDEKNLAQVSTNLLD
FEVTALHTVYEETCREAQELSLPVVGSQLVGLVPLKALLDAAAFYCEKENLFILEEEQRI
RLVVSRLGLDSLCPFSPKERIIEYLVPERGPERGLGSKSLRAFVGEVGARSAAPGGGSVA
AAAAAMGAALGSMVGLMTYGRRQFQSLDTTMRRLIPPFREASAKLTTLVDADAEAFTAYL
EAMRLPKNTPEEKDRRTAALQEGLRRAVSVPLTLAETVASLWPALQELARCGNLACRSDL
QVAAKALEMGVFGAYFNVLINLRDITDEAFKDQIHHRVSSLLQEAKTQAALVLDCLETRQ
E
NT seq
1626 nt
NT seq
+upstream
nt +downstream
nt
atgtcccagctggtggaatgcgtccccaacttttcggaggggaagaaccaggaggtgatc
gacgccatctctggagccatcacacagaccccgggctgcgtgctgctggatgtggacgca
ggcccttccaccaaccgcaccgtgtacaccttcgtggggccgccggagtgcgtggtggag
ggggccctcaacgctgcccgggtagcttcccgacttatcgacatgagcaggcaccaagga
gagcacccccgcatgggggccctagacgtctgccccttcatccccgtgaggggcgtcagc
gtggatgagtgtgtgctctgcgcccaggcctttggccagaggctggcagaggagctggac
gtgccagtttacctgtacggcgaggcagccaggatggacagtcgccggaccctgccggcc
atccgggccggggagtacgaggccctccctaagaagctccagcaggccgactgggcgccc
gactttggtcccagctcctttgtccccagttggggggccacggccacgggggcgaggaag
ttcctcattgcttttaacatcaacctgctcggcacaaaggagcaagcccaccgcatcgcg
ctcaacctgcgggagcagggccgcgggaaggaccagccaggacgtctgaagaaagttcag
ggcattggctggtacctggatgagaagaacctggctcaggtgtccaccaatcttctggac
tttgaggtcacggcactgcacacggtctacgaggagacctgccgagaagcacaggagctg
agcctcccagtggtgggctcacagctggtgggcctggtgcccctgaaggctctgctggat
gcggccgccttctactgcgagaaggagaacctcttcatcctggaggaggagcagcggatc
aggctggtggtgagccggctgggcctggactccctgtgccccttcagccctaaggagcgg
atcatcgagtacctggtccctgagcgcgggcctgagcgaggcctgggcagcaagtccctg
cgcgccttcgtgggggaggtgggtgcccgctctgcggcccccgggggcggctcggtggcg
gcggccgctgcggccatgggtgcggcgctgggctccatggtgggcctcatgacctacggg
cggcgccaattccagtccctggacacgacgatgcggcgcctgatcccgcccttccgcgag
gcttcggccaagctaaccacgctggtggatgccgacgccgaggccttcaccgcctacctg
gaagcaatgaggctccccaagaacacacctgaggaaaaggacaggcgcacggcggcccta
caggagggtctgaggcgggcagtctctgtgccgctgacgctggcggagacggtggcctcg
ctgtggccggccctgcaggaactggcccggtgtgggaacctggcctgccggtcagacctc
caggtggcggccaaagccctggagatgggcgtgtttggcgcatatttcaacgtgctcatc
aacctgagggacatcacagacgaggcatttaaggaccagatccaccatcgtgtttccagc
ctcctgcaggaagccaagacccaggctgcactggtgctggactgcttggagacccggcag
gagtga
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