Homo sapiens (human): 169355 Help Entry 169355            CDS       T01001                                  Symbol IDO2, INDOL1 Name (RefSeq) indoleamine 2,3-dioxygenase 2   KO K00463   indoleamine 2,3-dioxygenase [EC:1.13.11.52] Organism hsa  Homo sapiens (human) Pathway hsa00380   Tryptophan metabolism hsa01100   Metabolic pathways hsa01240   Biosynthesis of cofactors hsa05143   African trypanosomiasis Module hsa_M00038   Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate hsa_M00912   NAD biosynthesis, tryptophan => quinolinate => NAD Network nt06036  Lysine degradation   Element N01723   NAD biosynthesis Drug target Indoximod:  D10640 Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09105 Amino acid metabolism    00380 Tryptophan metabolism     169355 (IDO2)  09160 Human Diseases   09174 Infectious disease: parasitic    05143 African trypanosomiasis     169355 (IDO2) Enzymes [BR:hsa01000]  1. Oxidoreductases   1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)    1.13.11  With incorporation of two atoms of oxygen     1.13.11.52  indoleamine 2,3-dioxygenase      169355 (IDO2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IDO Motif Other DBs NCBI-GeneID:  169355 NCBI-ProteinID:  NP_001382135 OMIM:  612129 HGNC:  27269 Ensembl:  ENSG00000188676 UniProt:  Q6ZQW0 LinkDB All DBs Position 8:39934651..40016392 Genome browser AA seq 407 aa AA seqDB search MEPHRPNVKTAVPLSLESYHISEEYGFLLPDSLKELPDHYRPWMEIANKLPQLIDAHQLQ AHVDKMPLLSCQFLKGHREQRLAHLVLSFLTMGYVWQEGEAQPAEVLPRNLALPFVEVSR NLGLPPILVHSDLVLTNWTKKDPDGFLEIGNLETIISFPGGESLHGFILVTALVEKEAVP GIKALVQATNAILQPNQEALLQALQRLRLSIQDITKTLGQMHDYVDPDIFYAGIRIFLSG WKDNPAMPAGLMYEGVSQEPLKYSGGSAAQSTVLHAFDEFLGIRHSKESGDFLYRMRDYM PPSHKAFIEDIHSAPSLRDYILSSGQDHLLTAYNQCVQALAELRSYHITMVTKYLITAAA KAKHGKPNHLPGPPQALKDRGTGGTAVMSFLKSVRDKTLESILHPRG NT seq 1224 nt NT seq  +upstreamnt  +downstreamnt atggagccccacagaccgaatgtgaagacagcagtgccattgtctttggaaagctatcac atatctgaagagtatggctttcttcttccagattctctgaaagaacttccagatcattat aggccttggatggaaattgccaacaaacttcctcaattgattgatgctcaccagcttcaa gctcatgtggacaagatgcccctgctgagctgccagttcctgaagggtcaccgggagcag cgcctggcccacctggtcctgagcttcctcaccatgggttatgtctggcaggaaggagag gcgcagcctgcagaggtcctgccaaggaatcttgcccttccatttgtcgaagtctccagg aacttggggctccctcctatcctggtccactcagacttggtgctgacgaactggaccaaa aaagatccagacggattcctggaaattgggaacctggagaccatcatctcatttcctggg ggagagagcctgcatggttttatactggtgactgctttggtagagaaagaagcagtgcct gggataaaggctcttgttcaggccacgaatgctatcttgcagcccaaccaggaggccctg ctccaagccctgcagcgactgagactgtctattcaggacatcaccaaaaccttaggacag atgcatgattatgtagatccagacatattttatgcaggcatccggatctttctctctgga tggaaagacaacccagcaatgcctgcagggctgatgtatgaaggagtttcccaagagccc ctgaaatactccggcgggagtgcagctcagagcacagtgcttcatgcctttgatgagttc ttaggcattcgtcatagcaaggaaagtggtgactttctgtacagaatgagggattacatg cctccttcccataaggccttcatagaagacatccactcagcaccttccctgagggactac atcctgtcatctggacaggaccacttgctgacagcttataaccagtgtgtgcaggccctg gcagagctgcggagctatcacatcaccatggtcaccaaatacctcatcacagctgcagcc aaggcaaagcatgggaagccaaaccatctcccagggcctcctcaggctttaaaagacagg ggcacaggtggaaccgcagttatgagctttcttaagagtgtcagggataagaccttggag tcaatccttcacccacgtggttag

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