KEGG   Homo sapiens (human): 1855
Entry
1855              CDS       T01001                                 
Symbol
DVL1, DRS2, DVL, DVL1L1, DVL1P1
Name
(RefSeq) dishevelled segment polarity protein 1
  KO
K02353  segment polarity protein dishevelled
Organism
hsa  Homo sapiens (human)
Pathway
hsa04150  mTOR signaling pathway
hsa04310  Wnt signaling pathway
hsa04330  Notch signaling pathway
hsa04390  Hippo signaling pathway
hsa04550  Signaling pathways regulating pluripotency of stem cells
hsa04916  Melanogenesis
hsa04934  Cushing syndrome
hsa05010  Alzheimer disease
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05165  Human papillomavirus infection
hsa05200  Pathways in cancer
hsa05217  Basal cell carcinoma
hsa05224  Breast cancer
hsa05225  Hepatocellular carcinoma
hsa05226  Gastric cancer
Network
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06181  Salmonella
nt06215  WNT signaling (cancer)
nt06260  Colorectal cancer
nt06261  Gastric cancer
nt06263  Hepatocellular carcinoma
nt06270  Breast cancer
nt06271  Endometrial cancer
nt06274  Thyroid cancer
nt06505  WNT signaling
  Element
N00056  Wnt signaling pathway
N00059  FZD7-overexpression to Wnt signaling pathway
N00060  LRP6-overexpression to Wnt signaling pathway
N01427  WNT5A-ROR signaling pathway
N01444  NXN mutation to WNT5A-ROR signaling pathway
Disease
H00485  Robinow syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    1855 (DVL1)
   04330 Notch signaling pathway
    1855 (DVL1)
   04390 Hippo signaling pathway
    1855 (DVL1)
   04150 mTOR signaling pathway
    1855 (DVL1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    1855 (DVL1)
 09150 Organismal Systems
  09152 Endocrine system
   04916 Melanogenesis
    1855 (DVL1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    1855 (DVL1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    1855 (DVL1)
   05226 Gastric cancer
    1855 (DVL1)
   05217 Basal cell carcinoma
    1855 (DVL1)
   05224 Breast cancer
    1855 (DVL1)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    1855 (DVL1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    1855 (DVL1)
   05022 Pathways of neurodegeneration - multiple diseases
    1855 (DVL1)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    1855 (DVL1)
SSDB
Motif
Pfam: Dsh_C Dishevelled DIX PDZ DEP PDZ_6 Shufflon_N
Other DBs
NCBI-GeneID: 1855
NCBI-ProteinID: NP_001317240
OMIM: 601365
HGNC: 3084
Ensembl: ENSG00000107404
UniProt: O14640
Structure
LinkDB
Position
1:complement(1335278..1349418)
AA seq 695 aa
MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVK
EEIFDDNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPPPLERTGGIGDSRPPSF
HPNVASSRDGMDNETGTESMVSHRRERARRRNREEAARTNGHPRGDRRRDVGLPPDSAST
ALSSELESSSFVDSDEDGSTSRLSSSTEQSTSSRLIRKHKRRRRKQRLRQADRASSFSSI
TDSTMSLNIVTVTLNMERHHFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDM
LLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCWDPTPRSYFTVPRADPVRPIDP
AAWLSHTAALTGALPRYGTSPCSSAVTRTSSSSLTSSVPGAPQLEEAPLTVKSDMSAVVR
VMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLYTHVEGFKERREARKYASSLLKHGFL
RHTVNKITFSEQCYYVFGDLCSNLATLNLNSGSSGTSDQDTLAPLPHPAAPWPLGQGYPY
QYPGPPPCFPPAYQDPGFSYGSGSTGSQQSEGSKSSGSTRSSRRAPGREKERRAAGAGGS
GSESDHTAPSGVGSSWRERPAGQLSRGSSPRSQASATAPGLPPPHPTTKAYTVVGGPPGG
PPVRELAAVPPELTGSRQSFQKAMGNPCEFFVDIM
NT seq 2088 nt   +upstreamnt  +downstreamnt
atggcggagaccaagattatctaccacatggacgaggaggagacgccgtacctggtcaag
ctgcccgtggcccccgagcgcgtcacgctggccgacttcaagaacgtgctcagcaaccgg
cccgtgcacgcctacaaattcttctttaagtccatggaccaggacttcggggtggtgaag
gaggagatctttgatgacaatgccaagcttccctgcttcaacggccgcgtggtctcctgg
ctggtcctggctgagggtgctcactcggatgcggggtcccagggcacggacagccacaca
gacctgcccccgcctcttgagcggacaggcggcatcggggactcccggcccccctccttc
cacccaaatgtggccagcagccgtgacgggatggacaacgagacaggcacggagtccatg
gtcagtcaccggcgggagcgtgcccgacgccggaaccgcgaggaggccgcccggaccaat
gggcacccaaggggagaccgacggcgggatgtggggctgcccccagacagcgcgtccacc
gccctcagcagcgagcttgagtccagcagctttgtggactcggacgaggatggcagcacg
agcaggctcagcagctccacggagcagagcacctcatccagactcatccggaagcacaaa
cgccggcggaggaagcagcgccttcggcaggcggaccgggcctcctccttcagcagcata
accgactccaccatgtccctcaacatcgtcactgtcacgctcaacatggaaagacatcac
tttctgggcatcagcatcgtggggcagagcaacgaccgtggagacggcggcatctacatt
ggctccatcatgaagggcggggctgtggccgctgacggccgcatcgagcccggcgacatg
ttgctgcaggtgaatgacgtgaactttgagaacatgagcaatgacgatgccgtgcgggtg
ctgcgggagatcgtttcccagacggggcccatcagcctcactgtggccaagtgctgggac
ccaacgccccgaagctacttcaccgtcccacgggctgacccggtgcggcccatcgacccc
gccgcctggctgtcccacacggcggcactgacaggagccctgccccgctacggtacgagt
ccctgctccagcgccgtcacgcgcaccagctcctcctcactaaccagctccgtgcctggt
gctccacagctggaagaggcgccgctgacggtgaagagtgacatgagcgccgtcgtccgg
gtcatgcagctgccagactcgggactggagatccgcgaccgcatgtggctcaagatcacc
atcgccaatgccgtcatcggggcggacgtggtggactggctgtacacacacgtggagggc
ttcaaggagcggcgggaggcccggaagtacgccagcagcttgctgaagcacggcttcctg
cggcacacggtcaacaagatcaccttctccgagcagtgctactacgtcttcggggatctc
tgcagcaatctcgccaccctgaacctcaacagtggctccagtgggacttcggatcaggac
acgctggccccgctgccccacccggctgccccctggcctctgggtcagggctacccctac
cagtacccgggacccccaccctgcttcccgcctgcctaccaggacccgggctttagctat
ggcagcggcagcaccgggagtcagcagagtgaagggagcaaaagcagtgggtccacccgg
agcagccgccgggccccgggccgtgagaaggagcgtcgggcggcgggagctgggggcagt
ggcagtgaatcggatcacacggcaccgagtggggtggggagcagctggcgagagcgtccg
gccggccagctcagccgtggcagcagcccacgcagtcaggcctcggctaccgccccgggg
ctccccccgccccaccccacgaccaaggcctatacagtggtgggggggccacccggggga
ccccctgtccgggagctggctgccgtccccccggaattgacaggcagccgccagtccttc
cagaaggctatggggaacccctgcgagttcttcgtggacatcatgtga

KEGG   Homo sapiens (human): 1856
Entry
1856              CDS       T01001                                 
Symbol
DVL2
Name
(RefSeq) dishevelled segment polarity protein 2
  KO
K02353  segment polarity protein dishevelled
Organism
hsa  Homo sapiens (human)
Pathway
hsa04150  mTOR signaling pathway
hsa04310  Wnt signaling pathway
hsa04330  Notch signaling pathway
hsa04390  Hippo signaling pathway
hsa04550  Signaling pathways regulating pluripotency of stem cells
hsa04916  Melanogenesis
hsa04934  Cushing syndrome
hsa05010  Alzheimer disease
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05165  Human papillomavirus infection
hsa05200  Pathways in cancer
hsa05217  Basal cell carcinoma
hsa05224  Breast cancer
hsa05225  Hepatocellular carcinoma
hsa05226  Gastric cancer
Network
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06181  Salmonella
nt06215  WNT signaling (cancer)
nt06260  Colorectal cancer
nt06261  Gastric cancer
nt06263  Hepatocellular carcinoma
nt06270  Breast cancer
nt06271  Endometrial cancer
nt06274  Thyroid cancer
nt06505  WNT signaling
  Element
N00056  Wnt signaling pathway
N00059  FZD7-overexpression to Wnt signaling pathway
N00060  LRP6-overexpression to Wnt signaling pathway
N01427  WNT5A-ROR signaling pathway
N01444  NXN mutation to WNT5A-ROR signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    1856 (DVL2)
   04330 Notch signaling pathway
    1856 (DVL2)
   04390 Hippo signaling pathway
    1856 (DVL2)
   04150 mTOR signaling pathway
    1856 (DVL2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    1856 (DVL2)
 09150 Organismal Systems
  09152 Endocrine system
   04916 Melanogenesis
    1856 (DVL2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    1856 (DVL2)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    1856 (DVL2)
   05226 Gastric cancer
    1856 (DVL2)
   05217 Basal cell carcinoma
    1856 (DVL2)
   05224 Breast cancer
    1856 (DVL2)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    1856 (DVL2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    1856 (DVL2)
   05022 Pathways of neurodegeneration - multiple diseases
    1856 (DVL2)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    1856 (DVL2)
SSDB
Motif
Pfam: Dsh_C Dishevelled DIX DEP PDZ PDZ_6 Shufflon_N
Other DBs
NCBI-GeneID: 1856
NCBI-ProteinID: NP_004413
OMIM: 602151
HGNC: 3086
Ensembl: ENSG00000004975
UniProt: O14641
Structure
LinkDB
Position
17:complement(7225342..7234517)
AA seq 736 aa
MAGSSTGGGGVGETKVIYHLDEEETPYLVKIPVPAERITLGDFKSVLQRPAGAKYFFKSM
DQDFGVVKEEISDDNARLPCFNGRVVSWLVSSDNPQPEMAPPVHEPRAELAPPAPPLPPL
PPERTSGIGDSRPPSFHPNVSSSHENLEPETETESVVSLRRERPRRRDSSEHGAGGHRTG
GPSRLERHLAGYESSSTLMTSELESTSLGDSDEEDTMSRFSSSTEQSSASRLLKRHRRRR
KQRPPRLERTSSFSSVTDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIM
KGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVHKPGPIVLTVAKCWDPSPQ
AYFTLPRNEPIQPIDPAAWVSHSAALTGTFPAYPGSSSMSTITSGSSLPDGCEGRGLSVH
TDMASVTKAMAAPESGLEVRDRMWLKITIPNAFLGSDVVDWLYHHVEGFPERREARKYAS
GLLKAGLIRHTVNKITFSEQCYYVFGDLSGGCESYLVNLSLNDNDGSSGASDQDTLAPLP
GATPWPLLPTFSYQYPAPHPYSPQPPPYHELSSYTYGGGSASSQHSEGSRSSGSTRSDGG
AGRTGRPEERAPESKSGSGSESEPSSRGGSLRRGGEASGTSDGGPPPSRGSTGGAPNLRA
HPGLHPYGPPPGMALPYNPMMVVMMPPPPPPVPPAVQPPGAPPVRDLGSVPPELTASRQS
FHMAMGNPSEFFVDVM
NT seq 2211 nt   +upstreamnt  +downstreamnt
atggcgggtagcagcactgggggcggtggggttggggagacgaaggtgatttaccacctg
gatgaggaagagactccctacctggtgaagatccctgtccccgccgagcgcatcaccctc
ggcgatttcaagagcgtcctgcagcggcccgcgggcgccaagtactttttcaagtctatg
gatcaggatttcggggtggtgaaggaagaaatttcagatgacaacgcccgcctcccctgc
ttcaacggaagggtggtatcctggctggtgtcctcagataatccccaacccgagatggcc
cctccagtccatgagcctcgggcagaactggcgcctccagccccacctttacctcctttg
ccacccgagaggaccagcggcattggggactcaaggcctccatccttccaccctaatgtg
tccagcagccatgagaatctggagcctgagacagaaaccgagtcagtagtgtcactgagg
cgggagcggcctcgcaggagagacagcagtgagcatggcgctgggggccacaggactggt
ggcccctcaaggctggagcgccacctggccggatacgagagctcctctaccctcatgacc
agcgagctggagagtaccagcctgggggactcggacgaggaggacaccatgagcaggttc
agcagctccacggagcagagcagtgcctcccgcctccttaagcgccaccggcggcgaagg
aagcagaggccaccccgcctggagaggacgtcatccttcagcagcgtcacagattccaca
atgtctctcaatatcatcacagtcacgctaaacatggagaagtacaacttcctgggtatc
tccattgttggccagagcaatgagcggggagacggaggcatctacattggctccatcatg
aagggtggggctgtggcggccgacgggcgcattgagccaggggacatgcttttgcaggtg
aatgacatgaactttgagaacatgagcaacgatgacgctgtgcgggtgctgagggacatt
gtgcacaagcctggccccattgtgctgactgtggccaagtgctgggatccctctcctcag
gcctatttcactctcccccgaaatgagcccatccagccaattgaccctgctgcctgggtg
tcccattccgcggctctgactggcaccttcccagcctatccaggttcctcctccatgagc
accattacatctggatcgtctttgcctgatggctgtgaaggccggggtctctccgtccat
acggacatggcatcggtgaccaaggccatggcagctccagagtctggactggaagtccgg
gaccgcatgtggctcaagatcaccatccctaatgcctttctgggctcggatgtggttgac
tggctctaccatcacgtggagggctttcctgagcggcgggaggcccgcaagtatgccagc
gggctgctcaaagcaggcctgatccgacacaccgtcaacaagatcaccttctctgagcag
tgctattacgtcttcggagacctcagtggtggctgtgagagctacctagtcaacctgtct
ctcaatgacaacgatggctccagtggggcttcagaccaggataccctggctcctctgcct
ggggccaccccctggcccctgctgcccactttctcctaccaataccctgccccacacccc
tacagcccgcagcctccaccctaccatgagctttcatcttacacctatggtgggggcagt
gccagcagccagcatagtgagggcagccggagcagtgggtcgacacggagtgatgggggg
gcagggcgcacggggaggcccgaggagcgggcccccgagtccaagtccggcagtggcagt
gagtctgagccctccagccgagggggcagccttcggcggggtggggaagcaagtgggact
agcgatgggggccctcctccatccagaggctcaactgggggtgcccctaatctccgagcc
cacccagggctccatccctatggaccgccccctggcatggccctcccctacaaccccatg
atggtggtcatgatgcccccacctccacctccagtccctccagcagtgcagcctccgggg
gcccctccagtcagagacctgggctctgtgcccccagaactgacagccagccgccaaagc
ttccacatggccatgggcaatcccagcgagttctttgtggatgttatgtag

KEGG   Homo sapiens (human): 1857
Entry
1857              CDS       T01001                                 
Symbol
DVL3, DRS3
Name
(RefSeq) dishevelled segment polarity protein 3
  KO
K02353  segment polarity protein dishevelled
Organism
hsa  Homo sapiens (human)
Pathway
hsa04150  mTOR signaling pathway
hsa04310  Wnt signaling pathway
hsa04330  Notch signaling pathway
hsa04390  Hippo signaling pathway
hsa04550  Signaling pathways regulating pluripotency of stem cells
hsa04916  Melanogenesis
hsa04934  Cushing syndrome
hsa05010  Alzheimer disease
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05165  Human papillomavirus infection
hsa05200  Pathways in cancer
hsa05217  Basal cell carcinoma
hsa05224  Breast cancer
hsa05225  Hepatocellular carcinoma
hsa05226  Gastric cancer
Network
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06181  Salmonella
nt06215  WNT signaling (cancer)
nt06260  Colorectal cancer
nt06261  Gastric cancer
nt06263  Hepatocellular carcinoma
nt06270  Breast cancer
nt06271  Endometrial cancer
nt06274  Thyroid cancer
nt06505  WNT signaling
  Element
N00056  Wnt signaling pathway
N00059  FZD7-overexpression to Wnt signaling pathway
N00060  LRP6-overexpression to Wnt signaling pathway
N01427  WNT5A-ROR signaling pathway
N01444  NXN mutation to WNT5A-ROR signaling pathway
Disease
H00485  Robinow syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    1857 (DVL3)
   04330 Notch signaling pathway
    1857 (DVL3)
   04390 Hippo signaling pathway
    1857 (DVL3)
   04150 mTOR signaling pathway
    1857 (DVL3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    1857 (DVL3)
 09150 Organismal Systems
  09152 Endocrine system
   04916 Melanogenesis
    1857 (DVL3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    1857 (DVL3)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    1857 (DVL3)
   05226 Gastric cancer
    1857 (DVL3)
   05217 Basal cell carcinoma
    1857 (DVL3)
   05224 Breast cancer
    1857 (DVL3)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    1857 (DVL3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    1857 (DVL3)
   05022 Pathways of neurodegeneration - multiple diseases
    1857 (DVL3)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    1857 (DVL3)
SSDB
Motif
Pfam: Dsh_C Dishevelled DIX DEP PDZ PDZ_6 Shufflon_N
Other DBs
NCBI-GeneID: 1857
NCBI-ProteinID: NP_004414
OMIM: 601368
HGNC: 3087
Ensembl: ENSG00000161202
UniProt: Q92997
Structure
LinkDB
Position
3:184155377..184173614
AA seq 716 aa
MGETKIIYHLDGQETPYLVKLPLPAERVTLADFKGVLQRPSYKFFFKSMDDDFGVVKEEI
SDDNAKLPCFNGRVVSWLVSAEGSHPDPAPFCADNPSELPPPMERTGGIGDSRPPSFHPH
AGGGSQENLDNDTETDSLVSAQRERPRRRDGPEHATRLNGTAKGERRREPGGYDSSSTLM
SSELETTSFFDSDEDDSTSRFSSSTEQSSASRLMRRHKRRRRKQKVSRIERSSSFSSITD
STMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLL
QVNEINFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPSPRGCFTLPRSEPIRPIDPAA
WVSHTAAMTGTFPAYGMSPSLSTITSTSSSITSSIPDTERLDDFHLSIHSDMAAIVKAMA
SPESGLEVRDRMWLKITIPNAFIGSDVVDWLYHNVEGFTDRREARKYASNLLKAGFIRHT
VNKITFSEQCYYIFGDLCGNMANLSLHDHDGSSGASDQDTLAPLPHPGAAPWPMAFPYQY
PPPPHPYNPHPGFPELGYSYGGGSASSQHSEGSRSSGSNRSGSDRRKEKDPKAGDSKSGG
SGSESDHTTRSSLRGPRERAPSERSGPAASEHSHRSHHSLASSLRSHHTHPSYGPPGVPP
LYGPPMLMMPPPPAAMGPPGAPPGRDLASVPPELTASRQSFRMAMGNPSEFFVDVM
NT seq 2151 nt   +upstreamnt  +downstreamnt
atgggcgagaccaagatcatctaccacttggatgggcaggagacgccgtaccttgtgaag
ctgcccctgcccgccgagcgcgtcaccttggcggactttaagggcgttttgcagcgaccc
agctataagttcttcttcaagtctatggacgacgatttcggagtggtgaaggaggagatc
tcggatgacaatgccaagctaccatgcttcaatggccgggtggtgtcctggctggtgtca
gctgagggctcacacccagacccagcccccttctgtgctgataacccatcggagctgcca
ccacctatggagcgcacgggaggcatcggggactcccgacccccatccttccaccctcat
gctggtgggggcagccaggagaacctggacaatgacacagagacggactctttggtgtct
gcccagcgagagcggccacgccggagggatggcccagagcatgcaacccggctaaatgga
actgcgaagggggaacggcggcgagaaccagggggttatgatagctcatccacccttatg
agcagtgagctggagaccaccagcttctttgactcagatgaggatgactccaccagcagg
ttcagcagctccacagaacagagcagtgcctcacgcctgatgagaagacacaagcggcgg
cggcggaagcagaaggtttctcggattgagcggtcctcgtccttcagcagcatcacggac
tccaccatgtcactcaacatcatcacggtcactctcaacatggaaaaatataacttcttg
ggcatctccattgtgggccaaagcaacgagcgtggtgacggcggcatctacattggctct
atcatgaagggtggggccgtggctgctgatggacgcatcgagccaggagatatgttgtta
caggtaaacgagatcaactttgagaacatgagtaatgacgatgcagtccgggtactgcgg
gagattgtgcacaaaccggggcccatcaccctgactgtagccaagtgctgggacccaagt
ccacgtggttgcttcacattgcccaggagcgagcccatccggcccattgaccctgcggcc
tgggtctcccacactgcagccatgaccggcaccttccctgcatacggcatgagcccctcc
ctgagcaccatcacctccaccagctcctccatcaccagttccatccctgacacagagcgc
ctagacgacttccacttgtccatccacagtgacatggctgccatcgtaaaagccatggcc
tcccctgaatcagggttggaggtccgtgaccgcatgtggctcaagattaccatccctaat
gctttcatcggctcagatgtggtggactggctgtaccacaatgtggaaggcttcacggac
cggagggaggcccgcaagtatgccagcaacctgctgaaagctggcttcatccgccatacc
gtcaacaagatcaccttctccgagcagtgctactacatcttcggtgacctctgcggcaac
atggccaacctgtctctccacgatcacgatggctccagtggcgcctctgaccaggacaca
ctggcccctttgccgcacccgggggccgccccttggcccatggctttcccgtaccagtac
ccgccacccccgcacccatacaacccgcacccgggcttcccggagctgggctacagctac
ggcgggggcagcgccagcagtcagcacagcgaaggcagtcggagcagtggctccaaccgt
agcggcagcgatcggaggaaggagaaggacccgaaggccggggactccaagtccgggggc
agcggcagcgaatcggaccacaccacacgcagcagcctgcgggggccgcgggagcgggcg
cccagcgagcgctcagggccggcggccagcgagcacagccaccgcagccaccattccctg
gccagcagccttcgcagccaccacacacacccgagctacggtcctcccggagtgccccct
ctctacggcccccccatgctgatgatgcccccgccgcccgcggccatggggcccccagga
gcccctccgggccgcgacctggcctcagtgcccccggaactgaccgccagcagacagtcc
ttccgcatggccatgggaaaccccagtgagttctttgtggatgtgatgtga

KEGG   Homo sapiens (human): 10023
Entry
10023             CDS       T01001                                 
Symbol
FRAT1
Name
(RefSeq) FRAT regulator of Wnt signaling pathway 1
  KO
K03069  frequently rearranged in advanced T-cell lymphomas 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04310  Wnt signaling pathway
hsa05010  Alzheimer disease
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05200  Pathways in cancer
hsa05224  Breast cancer
hsa05225  Hepatocellular carcinoma
hsa05226  Gastric cancer
Network
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06181  Salmonella
nt06215  WNT signaling (cancer)
nt06260  Colorectal cancer
nt06261  Gastric cancer
nt06263  Hepatocellular carcinoma
nt06270  Breast cancer
nt06271  Endometrial cancer
nt06274  Thyroid cancer
nt06505  WNT signaling
  Element
N00056  Wnt signaling pathway
N00059  FZD7-overexpression to Wnt signaling pathway
N00060  LRP6-overexpression to Wnt signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    10023 (FRAT1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    10023 (FRAT1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    10023 (FRAT1)
   05226 Gastric cancer
    10023 (FRAT1)
   05224 Breast cancer
    10023 (FRAT1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    10023 (FRAT1)
   05022 Pathways of neurodegeneration - multiple diseases
    10023 (FRAT1)
SSDB
Motif
Pfam: GSK-3_bind
Other DBs
NCBI-GeneID: 10023
NCBI-ProteinID: NP_005470
OMIM: 602503
HGNC: 3944
Ensembl: ENSG00000165879
UniProt: Q92837
Structure
LinkDB
Position
10:97319271..97321915
AA seq 279 aa
MPCRREEEEEAGEEAEGEEEEEDSFLLLQQSVALGSSGEVDRLVAQIGETLQLDAAQHSP
ASPCGPPGAPLRAPGPLAAAVPADKARSPAVPLLLPPALAETVGPAPPGVLRCALGDRGR
VRGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQGIPQPLSGPCRRGWLRGAAASR
RLQQRRGSQPETRTGDDDPHRLLQQLVLSGNLIKEAVRRLHSRRLQLRAKLPQRPLLGPL
SAPVHEPPSPRSPRAACSDPGASGRAQLRTGDGVLVPGS
NT seq 840 nt   +upstreamnt  +downstreamnt
atgccgtgccggagggaggaggaagaggaagccggcgaggaggcggagggggaggaagag
gaggaggacagcttcctcctactgcagcagtcagtggcgctgggcagctcgggcgaggtg
gaccggctggtggcccagatcggcgagacgctgcagctggacgcggcgcagcacagcccg
gcctcgccgtgcgggcccccgggggcgccgctgcgggccccggggcccctggctgcggcg
gtgccggcggacaaggccaggtccccggcggtgccgctgctgctgccgcccgcgttggcg
gagactgtgggcccggcgccccctggggtcctgcgctgcgccctgggggaccgcggccgc
gtgcggggccgcgctgcgccctactgcgtggccgagctcgccacaggccccagcgcgctg
tccccactgccccctcaggccgaccttgatgggcctccgggagctggcaagcagggcatc
ccgcagccgctgtcgggtccgtgccggcgaggatggctccggggcgccgccgcctcccgc
cgcctgcagcagcgacgcgggtcccaaccagaaacccgcacaggcgacgacgacccgcac
cggcttctgcagcagctagtgctctctggaaacctcatcaaggaggccgtgcgaaggctt
cattcgcgacggctgcagttacgtgcaaagcttccccaacgcccgctcctgggacctctg
tcggccccggtgcatgaacccccttcgcctcgcagccctcgcgcggcctgcagtgaccct
ggcgcctccgggagggcgcagctcagaactggcgacggcgttcttgtgcctggcagctaa

KEGG   Homo sapiens (human): 23401
Entry
23401             CDS       T01001                                 
Symbol
FRAT2, FRAT-2
Name
(RefSeq) FRAT regulator of Wnt signaling pathway 2
  KO
K03096  frequently rearranged in advanced T-cell lymphomas 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04310  Wnt signaling pathway
hsa05010  Alzheimer disease
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05200  Pathways in cancer
hsa05224  Breast cancer
hsa05225  Hepatocellular carcinoma
hsa05226  Gastric cancer
Network
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06181  Salmonella
nt06215  WNT signaling (cancer)
nt06260  Colorectal cancer
nt06261  Gastric cancer
nt06263  Hepatocellular carcinoma
nt06270  Breast cancer
nt06271  Endometrial cancer
nt06274  Thyroid cancer
nt06505  WNT signaling
  Element
N00056  Wnt signaling pathway
N00059  FZD7-overexpression to Wnt signaling pathway
N00060  LRP6-overexpression to Wnt signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    23401 (FRAT2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    23401 (FRAT2)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    23401 (FRAT2)
   05226 Gastric cancer
    23401 (FRAT2)
   05224 Breast cancer
    23401 (FRAT2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    23401 (FRAT2)
   05022 Pathways of neurodegeneration - multiple diseases
    23401 (FRAT2)
SSDB
Motif
Pfam: GSK-3_bind
Other DBs
NCBI-GeneID: 23401
NCBI-ProteinID: NP_036215
OMIM: 605006
HGNC: 16048
Ensembl: ENSG00000181274
UniProt: O75474
LinkDB
Position
10:complement(97332497..97334729)
AA seq 233 aa
MPCRREEEEEAGEEAEGEEEEDDSFLLLQQSVTLGSSGEVDRLVAQIGETLQLDAAQDSP
ASPCAPPGVPLRAPGPLAAAVPADKARPPAVPLLLPPASAETVGPAPSGALRCALGDRGR
VRGRAAPYCVAEVAAGPSALPGPCRRGWLRDAVTSRRLQQRRWTQAGARAGDDDPHRLLQ
QLVLSGNLIKEAVRRLQRAVAAVAATGPASAPGPGGGRSGPDRIALQPSGSLL
NT seq 702 nt   +upstreamnt  +downstreamnt
atgccgtgccggagggaggaggaagaggaagccggcgaggaggcggagggggaggaagag
gaggacgacagcttcctcctgctgcagcagtcggtgacgctgggcagctcgggcgaggtg
gaccggctggtggcccagatcggcgagacgctgcagctggacgcggcgcaggacagcccg
gcctcgccgtgcgcgcccccgggggtgccgctgcgggccccggggcccctggctgcggcg
gtgccggcggacaaggcccggcccccggcggtgccgctgctgctgccgcccgcttcggct
gagacggtgggcccggcgccctctggggccctgcgctgcgccctaggggaccgcggccgc
gtgcgcggacgcgctgcgccctactgcgtggcggaggtcgccgcaggccccagcgcgctg
ccggggccgtgccggcgaggatggctcagggacgcggtcacctcccgccgcttgcagcag
cgccgatggacccaagccggggcacgcgccggcgacgacgacccgcatcggctcctccag
cagctcgtgctctcgggaaacctcatcaaggaagccgtgcggagactccaacgagccgtc
gccgcggttgcagccacgggccccgcaagcgcccctgggcccgggggaggccgcagcgga
cctgaccgcattgccctgcagccctcaggctccttgctctga

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