Homo sapiens (human): 2048
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Entry
2048 CDS
T01001
Symbol
EPHB2, BDPLT22, CAPB, DRT, EK5, EPHT3, ERK, Hek5, PCBC, Tyro5
Name
(RefSeq) EPH receptor B2
KO
K05111
Eph receptor B2 [EC:
2.7.10.1
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04360
Axon guidance
Network
nt06541
Cytoskeleton in neurons
Element
N01858
EFNB1-MAPT axon guidance signaling
Disease
H01235
Bleeding disorder platelet-type
Drug target
Sitravatinib (
DG03045
):
D11140
D11541
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09158 Development and regeneration
04360 Axon guidance
2048 (EPHB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
2048 (EPHB2)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
2048 (EPHB2)
Protein kinases [BR:
hsa01001
]
Receptor tyrosine kinases (RTK)
EPH family [OT]
2048 (EPHB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Ephrin_lbd
Pkinase
fn3
EphA2_TM
SAM_1
SAM_2
Ephrin_rec_like
Ig_DSCAM-DSCAML_C
Pur_ac_phosph_N
CRLF2-like_D2
ABC1
SusE
cEGF
Kdo
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
2048
NCBI-ProteinID:
NP_001296122
OMIM:
600997
HGNC:
3393
Ensembl:
ENSG00000133216
UniProt:
P29323
Q6NVW1
Q4LE53
Structure
PDB
PDBj
LinkDB
All DBs
Position
1:22710838..22921500
Genome browser
AA seq
1055 aa
AA seq
DB search
MALRRLGAALLLLPLLAAVEETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQ
VCNVFESSQNNWLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADF
DSATKTFPNWMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQD
YGGCMSLIAVRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLY
CNGDGEWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGA
TNCVCRNGYYRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNI
ICKSCGSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPF
SPQFASVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSE
YNATAIKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQEK
LPLIIGSSAAGLVFLIAVVVIAIVCNRRGFERADSEYTDKLQHYTSGHMTPGMKIYIDPF
TYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYT
EKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTV
IQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTY
TSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIE
QDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGI
NLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVTL
AGHQKKILNSIQVMRAQMNQIQSVEGQPLARRPRATGRTKRCQPRDVTKKTCNSNDGKKK
GMGKKKTDPGRGREIQGIFFKEDSHKESNDCSCGG
NT seq
3168 nt
NT seq
+upstream
nt +downstream
nt
atggctctgcggaggctgggggccgcgctgctgctgctgccgctgctcgccgccgtggaa
gaaacgctaatggactccactacagcgactgctgagctgggctggatggtgcatcctcca
tcagggtgggaagaggtgagtggctacgatgagaacatgaacacgatccgcacgtaccag
gtgtgcaacgtgtttgagtcaagccagaacaactggctacggaccaagtttatccggcgc
cgtggcgcccaccgcatccacgtggagatgaagttttcggtgcgtgactgcagcagcatc
cccagcgtgcctggctcctgcaaggagaccttcaacctctattactatgaggctgacttt
gactcggccaccaagaccttccccaactggatggagaatccatgggtgaaggtggatacc
attgcagccgacgagagcttctcccaggtggacctgggtggccgcgtcatgaaaatcaac
accgaggtgcggagcttcggacctgtgtcccgcagcggcttctacctggccttccaggac
tatggcggctgcatgtccctcatcgccgtgcgtgtcttctaccgcaagtgcccccgcatc
atccagaatggcgccatcttccaggaaaccctgtcgggggctgagagcacatcgctggtg
gctgcccggggcagctgcatcgccaatgcggaagaggtggatgtacccatcaagctctac
tgtaacggggacggcgagtggctggtgcccatcgggcgctgcatgtgcaaagcaggcttc
gaggccgttgagaatggcaccgtctgccgaggttgtccatctgggactttcaaggccaac
caaggggatgaggcctgtacccactgtcccatcaacagccggaccacttctgaaggggcc
accaactgtgtctgccgcaatggctactacagagcagacctggaccccctggacatgccc
tgcacaaccatcccctccgcgccccaggctgtgatttccagtgtcaatgagacctccctc
atgctggagtggacccctccccgcgactccggaggccgagaggacctcgtctacaacatc
atctgcaagagctgtggctcgggccggggtgcctgcacccgctgcggggacaatgtacag
tacgcaccacgccagctaggcctgaccgagccacgcatttacatcagtgacctgctggcc
cacacccagtacaccttcgagatccaggctgtgaacggcgttactgaccagagccccttc
tcgcctcagttcgcctctgtgaacatcaccaccaaccaggcagctccatcggcagtgtcc
atcatgcatcaggtgagccgcaccgtggacagcattaccctgtcgtggtcccagccggac
cagcccaatggcgtgatcctggactatgagctgcagtactatgagaaggagctcagtgag
tacaacgccacagccataaaaagccccaccaacacggtcaccgtgcagggcctcaaagcc
ggcgccatctatgtcttccaggtgcgggcacgcaccgtggcaggttacgggcgctacagc
ggcaagatgtacttccagaccatgacagaagccgagtaccagacaagcatccaggagaag
ttgccactcatcatcggctcctcggccgctggcctggtcttcctcattgctgtggttgtc
atcgccatcgtgtgtaacagacgggggtttgagcgtgctgactcggagtacacggacaag
ctgcaacactacaccagtggccacatgaccccaggcatgaagatctacatcgatcctttc
acctacgaggaccccaacgaggcagtgcgggagtttgccaaggaaattgacatctcctgt
gtcaaaattgagcaggtgatcggagcaggggagtttggcgaggtctgcagtggccacctg
aagctgccaggcaagagagagatctttgtggccatcaagacgctcaagtcgggctacacg
gagaagcagcgccgggacttcctgagcgaagcctccatcatgggccagttcgaccatccc
aacgtcatccacctggagggtgtcgtgaccaagagcacacctgtgatgatcatcaccgag
ttcatggagaatggctccctggactcctttctccggcaaaacgatgggcagttcacagtc
atccagctggtgggcatgcttcggggcatcgcagctggcatgaagtacctggcagacatg
aactatgttcaccgtgacctggctgcccgcaacatcctcgtcaacagcaacctggtctgc
aaggtgtcggactttgggctctcacgctttctagaggacgatacctcagaccccacctac
accagtgccctgggcggaaagatccccatccgctggacagccccggaagccatccagtac
cggaagttcacctcggccagtgatgtgtggagctacggcattgtcatgtgggaggtgatg
tcctatggggagcggccctactgggacatgaccaaccaggatgtaatcaatgccattgag
caggactatcggctgccaccgcccatggactgcccgagcgccctgcaccaactcatgctg
gactgttggcagaaggaccgcaaccaccggcccaagttcggccaaattgtcaacacgcta
gacaagatgatccgcaatcccaacagcctcaaagccatggcgcccctctcctctggcatc
aacctgccgctgctggaccgcacgatccccgactacaccagctttaacacggtggacgag
tggctggaggccatcaagatggggcagtacaaggagagcttcgccaatgccggcttcacc
tcctttgacgtcgtgtctcagatgatgatggaggacattctccgggttggggtcactttg
gctggccaccagaaaaaaatcctgaacagtatccaggtgatgcgggcgcagatgaaccag
attcagtctgtggagggccagccactcgccaggaggccacgggccacgggaagaaccaag
cggtgccagccacgagacgtcaccaagaaaacatgcaactcaaacgacggaaaaaaaaag
ggaatgggaaaaaagaaaacagatcctgggagggggcgggaaatacaaggaatatttttt
aaagaggattctcataaggaaagcaatgactgttcttgcgggggataa
DBGET
integrated database retrieval system
