Entry |
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Symbol |
ALDH7A1, ATQ1, EPD, EPEO4, PDE
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Name |
(RefSeq) aldehyde dehydrogenase 7 family member A1
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KO |
|
Organism |
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Pathway |
hsa00053 | Ascorbate and aldarate metabolism |
hsa00260 | Glycine, serine and threonine metabolism |
hsa00280 | Valine, leucine and isoleucine degradation |
hsa00330 | Arginine and proline metabolism |
|
Module |
hsa_M00032 | Lysine degradation, lysine => saccharopine => acetoacetyl-CoA |
hsa_M00135 | GABA biosynthesis, eukaryotes, putrescine => GABA |
hsa_M00555 | Betaine biosynthesis, choline => betaine |
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Network |
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Element |
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Disease |
H01247 | Pyridoxine-dependent epilepsy |
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Brite |
KEGG Orthology (KO) [BR:hsa00001]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
501 (ALDH7A1)
00053 Ascorbate and aldarate metabolism
501 (ALDH7A1)
00620 Pyruvate metabolism
501 (ALDH7A1)
09103 Lipid metabolism
00071 Fatty acid degradation
501 (ALDH7A1)
00561 Glycerolipid metabolism
501 (ALDH7A1)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
501 (ALDH7A1)
00280 Valine, leucine and isoleucine degradation
501 (ALDH7A1)
00310 Lysine degradation
501 (ALDH7A1)
00330 Arginine and proline metabolism
501 (ALDH7A1)
00340 Histidine metabolism
501 (ALDH7A1)
00380 Tryptophan metabolism
501 (ALDH7A1)
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
501 (ALDH7A1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
501 (ALDH7A1)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
501 (ALDH7A1)
Enzymes [BR:hsa01000]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.3 aldehyde dehydrogenase (NAD+)
501 (ALDH7A1)
1.2.1.8 betaine-aldehyde dehydrogenase
501 (ALDH7A1)
1.2.1.31 L-aminoadipate-semialdehyde dehydrogenase
501 (ALDH7A1)
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SSDB |
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Motif |
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Other DBs |
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Structure |
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LinkDB |
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Position |
5:complement(126541841..126595219)
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AA seq |
539 aa
MWRLPRALCVHAAKTSKLSGPWSRPAAFMSTLLINQPQYAWLKELGLREENEGVYNGSWG
GRGEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKIWADIPAPKRGEIVRQIGDA
LREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSGHALIE
QWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLED
NKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGN
NAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVG
NPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHD
ASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGI
VNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIKFQ |
NT seq |
1620 nt +upstreamnt +downstreamnt
atgtggcgccttcctcgcgcgctgtgtgtgcacgctgcaaagaccagcaagctctctgga
ccttggagcaggcctgccgccttcatgtccactctcctcatcaatcagccccagtatgcg
tggctgaaagagctggggctccgcgaggaaaacgagggcgtgtataatggaagctgggga
ggccggggagaggttattacgacctattgccctgctaacaacgagccaatagcaagagtc
cgacaggccagtgtggcagactatgaagaaactgtaaagaaagcaagagaagcatggaaa
atctgggcagatattcctgctccaaaacgaggagaaatagtaagacagattggcgatgcc
ttgcgggagaagatccaagtactaggaagcttggtgtctttggagatggggaaaatctta
gtggaaggtgtgggtgaagttcaggagtatgtggatatctgtgactatgctgttggttta
tcaaggatgattggaggacctatcttgccttctgaaagatctggccatgcactgattgag
cagtggaatcccgtaggcctggttggaatcatcacggcattcaatttccctgtggcagtg
tatggttggaacaacgccatcgccatgatctgtggaaatgtctgcctctggaaaggagct
ccaaccacttccctcattagtgtggctgtcacaaagataatagccaaggttctggaggac
aacaagctgcctggtgcaatttgttccttgacttgtggtggagcagatattggcacagca
atggccaaagatgaacgagtgaacctgctgtccttcactgggagcactcaggtgggaaaa
caggtgggcctgatggtgcaggagaggtttgggagaagtctgttggaacttggaggaaac
aatgccattattgcctttgaagatgcagacctcagcttagttgttccatcagctctcttc
gctgctgtgggaacagctggccagaggtgtaccactgcgaggcgactgtttatacatgaa
agcatccatgatgaggttgtaaacagacttaaaaaggcctatgcacagatccgagttggg
aacccatgggaccctaatgttctctatgggccactccacaccaagcaggcagtgagcatg
tttcttggagcagtggaagaagcaaagaaagaaggtggcacagtggtctatgggggcaag
gttatggatcgccctggaaattatgtagaaccgacaattgtgacaggtcttggccacgat
gcgtccattgcacacacagagacttttgctccgattctctatgtctttaaattcaagaat
gaagaagaggtctttgcatggaataatgaagtaaaacagggactttcaagtagcatcttt
accaaagatctgggcagaatctttcgctggcttggacctaaaggatcagactgtggcatt
gtaaatgtcaacattccaacaagtggggctgagattggaggtgcctttggaggagaaaag
cacactggtggtggcagggagtctggcagtgatgcctggaaacagtacatgagaaggtct
acttgtactatcaactacagtaaagaccttcctctggcccaaggaatcaagtttcagtaa |