Homo sapiens (human): 23649
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Entry
23649 CDS
T01001
Symbol
POLA2
Name
(RefSeq) DNA polymerase alpha 2, accessory subunit
KO
K02321
DNA polymerase alpha subunit B
Organism
hsa
Homo sapiens (human)
Pathway
hsa03030
DNA replication
Network
nt06509
DNA replication
Element
N01471
Origin unwinding and elongation
Drug target
Clofarabine:
D03546
<JP/US>
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09124 Replication and repair
03030 DNA replication
23649 (POLA2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
hsa03032
]
23649 (POLA2)
DNA replication proteins [BR:
hsa03032
]
Eukaryotic type
DNA Replication Elongation Factors
DNA polymerase alpha / primase complex
23649 (POLA2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_pol_E_B
DPOA2_OB
Pol_alpha_B_N
Motif
Other DBs
NCBI-GeneID:
23649
NCBI-ProteinID:
NP_002680
OMIM:
620063
HGNC:
30073
Ensembl:
ENSG00000014138
UniProt:
Q14181
Structure
PDB
PDBj
LinkDB
All DBs
Position
11:65261962..65305985
Genome browser
AA seq
598 aa
AA seq
DB search
MSASAQQLAEELQIFGLDCEEALIEKLVELCVQYGQNEEGMVGELIAFCTSTHKVGLTSE
ILNSFEHEFLSKRLSKARHSTCKDSGHAGARDIVSIQELIEVEEEEEILLNSYTTPSKGS
QKRAISTPETPLTKRSVSTRSPHQLLSPSSFSPSATPSQKYNSRSNRGEVVTSFGLAQGV
SWSGRGGAGNISLKVLGCPEALTGSYKSMFQKLPDIREVLTCKIEELGSELKEHYKIEAF
TPLLAPAQEPVTLLGQIGCDSNGKLNNKSVILEGDREHSSGAQIPVDLSELKEYSLFPGQ
VVIMEGINTTGRKLVATKLYEGVPLPFYQPTEEDADFEQSMVLVACGPYTTSDSITYDPL
LDLIAVINHDRPDVCILFGPFLDAKHEQVENCLLTSPFEDIFKQCLRTIIEGTRSSGSHL
VFVPSLRDVHHEPVYPQPPFSYSDLSREDKKQVQFVSEPCSLSINGVIFGLTSTDLLFHL
GAEEISSSSGTSDRFSRILKHILTQRSYYPLYPPQEDMAIDYESFYVYAQLPVTPDVLII
PSELRYFVKDVLGCVCVNPGRLTKGQVGGTFARLYLRRPAADGAERQSPCIAVQVVRI
NT seq
1797 nt
NT seq
+upstream
nt +downstream
nt
atgtccgcatccgcccagcagctggcggaggagctgcagatcttcggcctagactgcgag
gaggctctaattgagaaattggtagagctttgtgttcagtatggacagaatgaggaggga
atggtaggcgagcttatagccttctgcaccagcacacataaagttggccttacctcagag
atcctgaactcttttgagcatgagtttctgagcaaaagattatcgaaagccaggcatagt
acctgcaaggacagtggccatgcaggagctagagacattgtttccattcaagagctaatt
gaagtggaagaagaagaggaaatcctcttgaactcttacaccacaccttcaaagggttct
cagaagcgagctatctctaccccagaaacccccctaacaaaaaggagtgtgtcaactcgt
agcccccatcagctactctcaccgtcaagtttctctccaagtgctactccctcccagaaa
tacaactcacgaagtaaccgaggagaagtggttacctccttcggcttagcacagggagta
tcttggtctgggagaggaggagctggaaacatcagcctgaaggtcttgggatgtccagag
gcactaactgggagctacaaatccatgtttcagaagctcccagacattcgagaagttctg
acctgtaagatagaagaacttggcagcgaactcaaggaacattacaagattgaagctttc
actcctttgctagccccagcacaggagcctgtcactctgctgggccagattggctgtgat
agcaacgggaagctgaacaacaagtcagtgattctcgagggagaccgggaacattcctcg
ggtgctcaaattccagtggatttatctgagcttaaggaatattctctgtttcctggacag
gttgtaattatggaaggaatcaacaccactggtaggaaacttgttgccaccaaactctac
gagggtgtgccacttccattttatcagcccactgaagaggatgcagactttgagcaaagc
atggtcctggttgcctgtggaccatacaccacatctgacagcatcacgtatgaccccctg
cttgacctgattgctgtcatcaaccatgaccggccagatgtctgcatcctgtttggccct
ttcctggatgctaagcatgaacaggtggagaattgtctactgacaagtccatttgaagac
attttcaagcagtgtctacgaacaattattgaaggcacaagaagctccggctcccacctt
gtctttgtcccgtcattgagagatgtgcaccatgagcctgtgtacccccagccgcctttc
agctactccgatctgtctcgagaggacaaaaagcaagtacagtttgtgtccgagccctgc
agcctctccataaacggagtgatcttcggcttgacatccacagatctgcttttccacctg
ggggccgaggagatcagtagttcttccggaacttcagacagattcagccgaatactcaag
cacatcttgacccagaggagctactacccactctacccgccccaagaagacatggccatt
gactatgagtcgttctatgtttacgcacagctgcctgtcaccccagatgtcctcatcatc
ccgtcagagctgaggtacttcgtgaaggatgtcctcggctgtgtctgtgtgaaccctggg
cgccttaccaaagggcaggtgggaggcaccttcgcccgactctaccttaggaggccggca
gcggacggggcagagaggcagagcccatgcattgctgtgcaggtcgtcaggatctga
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