Homo sapiens (human): 2539
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Entry
2539 CDS
T01001
Symbol
G6PD, G6PD1
Name
(RefSeq) glucose-6-phosphate dehydrogenase
KO
K00036
glucose-6-phosphate 1-dehydrogenase [EC:
1.1.1.49
1.1.1.363
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00030
Pentose phosphate pathway
hsa00480
Glutathione metabolism
hsa01100
Metabolic pathways
hsa01200
Carbon metabolism
hsa05230
Central carbon metabolism in cancer
hsa05415
Diabetic cardiomyopathy
Module
hsa_M00004
Pentose phosphate pathway (Pentose phosphate cycle)
hsa_M00006
Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P
Network
nt06026
Glutathione biosynthesis
Element
N00905
NADP+ reduction
Disease
H00361
Malaria
H00668
Anemia due to disorders of glutathione metabolism
H01375
Glucose 6-phosphate dehydrogenase deficiency
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00030 Pentose phosphate pathway
2539 (G6PD)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
2539 (G6PD)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
2539 (G6PD)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
2539 (G6PD)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hsa04147
]
2539 (G6PD)
Enzymes [BR:
hsa01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.49 glucose-6-phosphate dehydrogenase (NADP+)
2539 (G6PD)
1.1.1.363 glucose-6-phosphate dehydrogenase [NAD(P)+]
2539 (G6PD)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
2539 (G6PD)
Exosomal proteins of colorectal cancer cells
2539 (G6PD)
Exosomal proteins of bladder cancer cells
2539 (G6PD)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
G6PD_C
G6PD_N
Motif
Other DBs
NCBI-GeneID:
2539
NCBI-ProteinID:
NP_001035810
OMIM:
305900
HGNC:
4057
Ensembl:
ENSG00000160211
UniProt:
P11413
A0A384NL00
Structure
PDB
LinkDB
All DBs
Position
X:complement(154531390..154547569)
Genome browser
AA seq
515 aa
AA seq
DB search
MAEQVALSRTQVCGILREELFQGDAFHQSDTHIFIIMGASGDLAKKKIYPTIWWLFRDGL
LPENTFIVGYARSRLTVADIRKQSEPFFKATPEEKLKLEDFFARNSYVAGQYDDAASYQR
LNSHMNALHLGSQANRLFYLALPPTVYEAVTKNIHESCMSQIGWNRIIVEKPFGRDLQSS
DRLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEP
FGTEGRGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPASTNSDDVRDEKVKVLKCISEVQA
NNVVLGQYVGNPDGEGEATKGYLDDPTVPRGSTTATFAAVVLYVENERWDGVPFILRCGK
ALNERKAEVRLQFHDVAGDIFHQQCKRNELVIRVQPNEAVYTKMMTKKPGMFFNPEESEL
DLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHQIELEKPKPI
PYIYGSRGPTEADELMKRVGFQYEGTYKWVNPHKL
NT seq
1548 nt
NT seq
+upstream
nt +downstream
nt
atggcagagcaggtggccctgagccggacccaggtgtgcgggatcctgcgggaagagctt
ttccagggcgatgccttccatcagtcggatacacacatattcatcatcatgggtgcatcg
ggtgacctggccaagaagaagatctaccccaccatctggtggctgttccgggatggcctt
ctgcccgaaaacaccttcatcgtgggctatgcccgttcccgcctcacagtggctgacatc
cgcaaacagagtgagcccttcttcaaggccaccccagaggagaagctcaagctggaggac
ttctttgcccgcaactcctatgtggctggccagtacgatgatgcagcctcctaccagcgc
ctcaacagccacatgaatgccctccacctggggtcacaggccaaccgcctcttctacctg
gccttgcccccgaccgtctacgaggccgtcaccaagaacattcacgagtcctgcatgagc
cagataggctggaaccgcatcatcgtggagaagcccttcgggagggacctgcagagctct
gaccggctgtccaaccacatctcctccctgttccgtgaggaccagatctaccgcatcgac
cactacctgggcaaggagatggtgcagaacctcatggtgctgagatttgccaacaggatc
ttcggccccatctggaaccgggacaacatcgcctgcgttatcctcaccttcaaggagccc
tttggcactgagggtcgcgggggctatttcgatgaatttgggatcatccgggacgtgatg
cagaaccacctactgcagatgctgtgtctggtggccatggagaagcccgcctccaccaac
tcagatgacgtccgtgatgagaaggtcaaggtgttgaaatgcatctcagaggtgcaggcc
aacaatgtggtcctgggccagtacgtggggaaccccgatggagagggcgaggccaccaaa
gggtacctggacgaccccacggtgccccgcgggtccaccaccgccacttttgcagccgtc
gtcctctatgtggagaatgagaggtgggatggggtgcccttcatcctgcgctgcggcaag
gccctgaacgagcgcaaggccgaggtgaggctgcagttccatgatgtggccggcgacatc
ttccaccagcagtgcaagcgcaacgagctggtgatccgcgtgcagcccaacgaggccgtg
tacaccaagatgatgaccaagaagccgggcatgttcttcaaccccgaggagtcggagctg
gacctgacctacggcaacagatacaagaacgtgaagctccctgacgcctatgagcgcctc
atcctggacgtcttctgcgggagccagatgcacttcgtgcgcagcgacgagctccgtgag
gcctggcgtattttcaccccactgctgcaccagattgagctggagaagcccaagcccatc
ccctatatttatggcagccgaggccccacggaggcagacgagctgatgaagagagtgggt
ttccagtatgagggcacctacaagtgggtgaacccccacaagctctga
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