KEGG   Homo sapiens (human): 27434
Entry
27434             CDS       T01001                                 
Symbol
POLM, Pol_Mu, Tdt-N
Name
(RefSeq) DNA polymerase mu
  KO
K03513  DNA polymerase mu [EC:2.7.7.7]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03450  Non-homologous end-joining
Network
nt06506  Double-strand break repair
  Element
N01445  Non-homologous end-joining
N01467  V(D)J recombination
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03450 Non-homologous end-joining
    27434 (POLM)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:hsa03400]
    27434 (POLM)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.7  DNA-directed DNA polymerase
     27434 (POLM)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    X-family DNA polymerases
     27434 (POLM)
SSDB
Motif
Pfam: DNA_pol_B_thumb DNA_pol_lambd_f HHH_8 DNA_pol_B_palm NTP_transf_2 BRCT Cdd1 SMC_ScpB HHH_5
Other DBs
NCBI-GeneID: 27434
NCBI-ProteinID: NP_037416
OMIM: 606344
HGNC: 9185
Ensembl: ENSG00000122678
Pharos: Q9NP87(Tbio)
UniProt: Q9NP87
Structure
LinkDB
Position
7:complement(44072062..44082530)
AA seq 494 aa
MLPKRRRARVGSPSGDAASSTPPSTRFPGVAIYLVEPRMGRSRRAFLTGLARSKGFRVLD
ACSSEATHVVMEETSAEEAVSWQERRMAAAPPGCTPPALLDISWLTESLGAGQPVPVECR
HRLEVAGPRKGPLSPAWMPAYACQRPTPLTHHNTGLSEALEILAEAAGFEGSEGRLLTFC
RAASVLKALPSPVTTLSQLQGLPHFGEHSSRVVQELLEHGVCEEVERVRRSERYQTMKLF
TQIFGVGVKTADRWYREGLRTLDDLREQPQKLTQQQKAGLQHHQDLSTPVLRSDVDALQQ
VVEEAVGQALPGATVTLTGGFRRGKLQGHDVDFLITHPKEGQEAGLLPRVMCRLQDQGLI
LYHQHQHSCCESPTRLAQQSHMDAFERSFCIFRLPQPPGAAVGGSTRPCPSWKAVRVDLV
VAPVSQFPFALLGWTGSKLFQRELRRFSRKEKGLWLNSHGLFDPEQKTFFQAASEEDIFR
HLGLEYLPPEQRNA
NT seq 1485 nt   +upstreamnt  +downstreamnt
atgctccccaaacggcggcgagcgcgggtcgggtcccctagcggcgatgccgcttcctcc
acgccgccctcgacgcgcttcccgggagtcgccatctacctggtcgagcctcgcatgggt
cgcagccgccgggccttcctcacaggcctggcgcgctccaaaggcttccgcgtccttgac
gcctgcagctccgaagcgacacatgttgtgatggaagagacctcagcagaggaggccgtc
agctggcaggagcgcaggatggcagctgctcccccgggttgcacccccccagctctgctg
gacataagctggttaacagagagcctgggagctgggcagcctgtacctgtggagtgccgg
caccgcctggaggtggctgggccaaggaaggggcctctgagcccagcatggatgcctgcc
tatgcctgccagcgccctacgcccctcacacaccacaacactggcctctccgaggctctg
gagatactggccgaggcagcaggctttgaaggcagtgagggccgcctcctcaccttctgc
agagcagcctcggtgctcaaggcccttcccagccctgtcacaaccctgagccagctgcag
gggcttccccactttggagaacactcctctagggttgtccaggagctgctggagcatgga
gtgtgtgaggaggtggagagagttcggcgctcagagaggtaccagaccatgaagctcttc
acccagatcttcggggtcggtgtgaagactgctgaccggtggtaccgggaaggactgcga
accttagatgacctccgagagcagccccagaaactaacccaacagcagaaagcggggctc
cagcaccaccaggacctgagcaccccagtcctgcggtccgatgtagatgccctgcagcag
gtggtggaggaagctgtggggcaggccctgcctggggccaccgtcacgctgaccggcggc
ttccgcagggggaagttgcagggccatgacgtggacttcctcatcacccaccccaaggag
ggtcaggaggcggggctgctgcctagagtgatgtgccgcctgcaggaccagggcctcatc
ctgtaccaccagcaccagcacagctgctgtgagtcccctacccgcctggcccaacagagc
cacatggacgcttttgagagaagtttctgcattttccgcctaccacaacctccaggggct
gctgtggggggatccacgaggccctgcccatcctggaaggccgtgagagtggacttggta
gttgcacccgtcagccagttccctttcgccctgctcggttggactggctccaagcttttc
cagcgggagctgcgccgcttcagccggaaggagaagggcctgtggctgaacagccatggg
ctgtttgacccggagcagaagacatttttccaagcggcttcagaggaagacatcttcaga
cacctgggccttgagtaccttcctccagagcagagaaacgcctga

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