| Entry |
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| Name |
Non-homologous end-joining
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| Definition |
TP53BP1+RIF1+PAXIP1 -> Ku == DNAPKC -> DNAPK+ARTEMIS -> DNAPK+POLX -> DNAPK == LIG4+XRCC4+XLF |
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| Expanded |
7158+55183+22976 -> 2547+7520 == 5591 -> 2547+7520+5591+64421 -> (2547+7520+5591)+(27343,27434,1791) -> 2547+7520+5591 == 3981+7518+79840 |
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| Class |
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| Type |
Reference
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| Pathway |
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| Gene |
| 7158 | TP53BP1; tumor protein p53 binding protein 1 |
| 55183 | RIF1; replication timing regulatory factor 1 |
| 22976 | PAXIP1; PAX interacting protein 1 |
| 2547 | XRCC6; X-ray repair cross complementing 6 |
| 7520 | XRCC5; X-ray repair cross complementing 5 |
| 5591 | PRKDC; protein kinase, DNA-activated, catalytic subunit |
| 64421 | DCLRE1C; DNA cross-link repair 1C |
| 27343 | POLL; DNA polymerase lambda |
| 27434 | POLM; DNA polymerase mu |
| 1791 | DNTT; DNA nucleotidylexotransferase |
| 7518 | XRCC4; X-ray repair cross complementing 4 |
| 79840 | NHEJ1; non-homologous end joining factor 1 |
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| Reference |
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| Authors |
Yue X, Bai C, Xie D, Ma T, Zhou PK |
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| Title |
DNA-PKcs: A Multi-Faceted Player in DNA Damage Response. |
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| Journal |
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| Reference |
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| Authors |
Rahimian E, Amini A, Alikarami F, Pezeshki SMS, Saki N, Safa M |
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| Title |
DNA repair pathways as guardians of the genome: Therapeutic potential and possible prognostic role in hematologic neoplasms. |
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| Journal |
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| Reference |
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| Authors |
De Gregoriis G, Ramos JA, Fernandes PV, Vignal GM, Brianese RC, Carraro DM, Monteiro AN, Struchiner CJ, Suarez-Kurtz G, Vianna-Jorge R, de Carvalho MA |
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| Title |
DNA repair genes PAXIP1 and TP53BP1 expression is associated with breast cancer prognosis. |
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| Journal |
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| LinkDB |
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