Homo sapiens (human): 2937 Help Entry 2937              CDS       T01001                                  Symbol GSS, GSHS, HEL-S-64p, HEL-S-88n Name (RefSeq) glutathione synthetase   KO K21456   glutathione synthase [EC:6.3.2.3] Organism hsa  Homo sapiens (human) Pathway hsa00270   Cysteine and methionine metabolism hsa00480   Glutathione metabolism hsa01100   Metabolic pathways hsa01240   Biosynthesis of cofactors hsa04216   Ferroptosis Module hsa_M00118   Glutathione biosynthesis, glutamate => glutathione Network nt06026  Glutathione biosynthesis nt06525  Ferroptosis   Element N01589   Glutathione biosynthesis Disease H00668   Anemia due to disorders of glutathione metabolism H02312   Glutathione synthetase deficiency Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09105 Amino acid metabolism    00270 Cysteine and methionine metabolism     2937 (GSS)   09106 Metabolism of other amino acids    00480 Glutathione metabolism     2937 (GSS)  09140 Cellular Processes   09143 Cell growth and death    04216 Ferroptosis     2937 (GSS)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:hsa04147]     2937 (GSS) Enzymes [BR:hsa01000]  6. Ligases   6.3  Forming carbon-nitrogen bonds    6.3.2  Acid-D-amino-acid ligases (peptide synthases)     6.3.2.3  glutathione synthase      2937 (GSS) Exosome [BR:hsa04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    2937 (GSS) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  GSH_synth_ATP GSH_synthase Motif Other DBs NCBI-GeneID:  2937 NCBI-ProteinID:  NP_000169 OMIM:  601002 HGNC:  4624 Ensembl:  ENSG00000100983 UniProt:  P48637 V9HWJ1 Structure PDB LinkDB All DBs Position 20:complement(34928432..34956027) Genome browser AA seq 474 aa AA seqDB search MATNWGSLLQDKQQLEELARQAVDRALAEGVLLRTSQEPTSSEVVSYAPFTLFPSLVPSA LLEQAYAVQMDFNLLVDAVSQNAAFLEQTLSSTIKQDDFTARLFDIHKQVLKEGIAQTVF LGLNRSDYMFQRSADGSPALKQIEINTISASFGGLASRTPAVHRHVLSVLSKTKEAGKIL SNNPSKGLALGIAKAWELYGSPNALVLLIAQEKERNIFDQRAIENELLARNIHVIRRTFE DISEKGSLDQDRRLFVDGQEIAVVYFRDGYMPRQYSLQNWEARLLLERSHAAKCPDIATQ LAGTKKVQQELSRPGMLEMLLPGQPEAVARLRATFAGLYSLDVGEEGDQAIAEALAAPSR FVLKPQREGGGNNLYGEEMVQALKQLKDSEERASYILMEKIEPEPFENCLLRPGSPARVV QCISELGIFGVYVRQEKTLVMNKHVGHLLRTKAIEHADGGVAAGVAVLDNPYPV NT seq 1425 nt NT seq  +upstreamnt  +downstreamnt atggccaccaactgggggagcctcttgcaggataaacagcagctagaggagctggcacgg caggccgtggaccgggccctggctgagggagtattgctgaggacctcacaggagcccact tcctcggaggtggtgagctatgccccattcacgctcttcccctcactggtccccagtgcc ctgctggagcaagcctatgctgtgcagatggacttcaacctgctagtggatgctgtcagc cagaacgctgccttcctggagcaaactctttccagcaccatcaaacaggatgactttacc gctcgtctctttgacatccacaagcaagtcctaaaagagggcattgcccagactgtgttc ctgggcctgaatcgctcagactacatgttccagcgcagcgcagatggctccccagccctg aaacagatcgaaatcaacaccatctctgccagctttgggggcctggcctcccggacccca gctgtgcaccgacatgttctcagtgtcctgagtaagaccaaagaagctggcaagatcctc tctaataatcccagcaagggactggccctgggaattgccaaagcctgggagctctacggc tcacccaatgctctggtgctactgattgctcaagagaaggaaagaaacatatttgaccag cgtgccatagagaatgagctactggccaggaacatccatgtgatccgacgaacatttgaa gatatctctgaaaaggggtctctggaccaagaccgaaggctgtttgtggatggccaggaa attgctgtggtttacttccgggatggctacatgcctcgtcagtacagtctacagaattgg gaagcacgtctactgctggagaggtcacatgctgccaagtgcccagacattgccacccag ctggctgggactaagaaggtgcagcaggagctaagcaggccgggcatgctggagatgttg ctccctggccagcctgaggctgtggcccgcctccgcgccacctttgctggcctctactca ctggatgtgggtgaagaaggggaccaggccatcgccgaggcccttgctgcccctagccgg tttgtgctaaagccccagagagagggtggaggtaacaacctatatggggaggaaatggta caggccctgaaacagctgaaggacagtgaggagagggcctcctacatcctcatggagaag atcgaacctgagccttttgagaattgcctgctacggcctggcagccctgcccgagtggtc cagtgcatttcagagctgggcatctttggggtctatgtcaggcaggaaaagacactcgtg atgaacaagcacgtggggcatctacttcgaaccaaagccatcgagcatgcagatggtggt gtggcagcgggagtggcagtcctggacaacccataccctgtgtga

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