Homo sapiens (human): 3655 Help Entry 3655              CDS       T01001                                  Symbol ITGA6, CD49f, ITGA6A, ITGA6B, JEB6, VLA-6 Name (RefSeq) integrin subunit alpha 6   KO K06485   integrin alpha 6 Organism hsa  Homo sapiens (human) Pathway hsa04151   PI3K-Akt signaling pathway hsa04510   Focal adhesion hsa04512   ECM-receptor interaction hsa04514   Cell adhesion molecules hsa04640   Hematopoietic cell lineage hsa04810   Regulation of actin cytoskeleton hsa04820   Cytoskeleton in muscle cells hsa05145   Toxoplasmosis hsa05165   Human papillomavirus infection hsa05200   Pathways in cancer hsa05222   Small cell lung cancer hsa05410   Hypertrophic cardiomyopathy hsa05412   Arrhythmogenic right ventricular cardiomyopathy hsa05414   Dilated cardiomyopathy Network nt06539  Cytoskeleton in muscle cells   Element N01815   Vinculin-talin-integrin macromolecular complex Disease H00586   Epidermolysis bullosa, junctional Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04151 PI3K-Akt signaling pathway     3655 (ITGA6)   09133 Signaling molecules and interaction    04512 ECM-receptor interaction     3655 (ITGA6)    04514 Cell adhesion molecules     3655 (ITGA6)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     3655 (ITGA6)   09142 Cell motility    04820 Cytoskeleton in muscle cells     3655 (ITGA6)    04810 Regulation of actin cytoskeleton     3655 (ITGA6)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     3655 (ITGA6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     3655 (ITGA6)   09162 Cancer: specific types    05222 Small cell lung cancer     3655 (ITGA6)   09172 Infectious disease: viral    05165 Human papillomavirus infection     3655 (ITGA6)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     3655 (ITGA6)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     3655 (ITGA6)    05412 Arrhythmogenic right ventricular cardiomyopathy     3655 (ITGA6)    05414 Dilated cardiomyopathy     3655 (ITGA6)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:hsa04147]     3655 (ITGA6)    04515 Cell adhesion molecules [BR:hsa04515]     3655 (ITGA6)    04090 CD molecules [BR:hsa04090]     3655 (ITGA6) Exosome [BR:hsa04147]  Exosomal proteins   Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)    3655 (ITGA6)   Exosomal proteins of breast milk    3655 (ITGA6) Cell adhesion molecules [BR:hsa04515]  Integrins   Integrin alpha subunits    3655 (ITGA6) CD molecules [BR:hsa04090]  Proteins   3655 (ITGA6) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Integrin_A_Ig_3 Integrin_A_Ig_1 Integrin_A_Ig_2 FG-GAP FG-GAP_3 Integrin_alpha LRR19-TM Motif Other DBs NCBI-GeneID:  3655 NCBI-ProteinID:  NP_001073286 OMIM:  147556 HGNC:  6142 Ensembl:  ENSG00000091409 UniProt:  P23229 Structure PDB LinkDB All DBs Position 2:172427336..172506459 Genome browser AA seq 1091 aa AA seqDB search MAAAGQLCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKR LLLVGAPRAEALPLQRANRTGGLYSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQ SQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLR GHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVG GETEHDESLVPVPANSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAH LLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGR WNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTK PTQVLKGISPYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNR IDLRQKTACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFR NQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQEPSSRRRVNSL PEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCTREGNQDKFSYLPIQKG VPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRELRAFP EKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINLKLETTSNQD NLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLG KPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRK KREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRCPLRGLDSKASLILRSRLWNST FLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQVRVTVFPSKTVAQYSGVPWWIILV AILAGILMLALLVFILWKCGFFKRSRYDDSVPRYHAVRIRKEEREIKDEKYIDNLEKKQW ITKWNENESYS NT seq 3276 nt NT seq  +upstreamnt  +downstreamnt atggccgccgccgggcagctgtgcttgctctacctgtcggcggggctcctgtcccggctc ggcgcagccttcaacttggacactcgggaggacaacgtgatccggaaatatggagacccc gggagcctcttcggcttctcgctggccatgcactggcaactgcagcccgaggacaagcgg ctgttgctcgtgggggccccgcgggcagaagcgcttccactgcagagagccaacagaacg ggagggctgtacagctgcgacatcaccgcccgggggccatgcacgcggatcgagtttgat aacgatgctgaccccacgtcagaaagcaaggaagatcagtggatgggggtcaccgtccag agccaaggtccagggggcaaggtcgtgacatgtgctcaccgatatgaaaaaaggcagcat gttaatacgaagcaggaatcccgagacatctttgggcggtgttatgtcctgagtcagaat ctcaggattgaagacgatatggatgggggagattggagcttttgtgatgggcgattgaga ggccatgagaaatttggctcttgccagcaaggtgtagcagctacttttactaaagacttt cattacattgtatttggagccccgggtacttataactggaaagggattgttcgtgtagag caaaagaataacactttttttgacatgaacatctttgaagatgggccttatgaagttggt ggagagactgagcatgatgaaagtctcgttcctgttcctgctaacagttacttaggtttt tctttggactcagggaaaggtattgtttctaaagatgagatcacttttgtatctggtgct cccagagccaatcacagtggagccgtggttttgctgaagagagacatgaagtctgcacat ctcctccctgagcacatattcgatggagaaggtctggcctcttcatttggctatgatgtg gcggtggtggacctcaacaaggatgggtggcaagatatagttattggagccccacagtat tttgatagagatggagaagttggaggtgcagtgtatgtctacatgaaccagcaaggcaga tggaataatgtgaagccaattcgtcttaatggaaccaaagattctatgtttggcattgca gtaaaaaatattggagatattaatcaagatggctacccagatattgcagttggagctccg tatgatgacttgggaaaggtttttatctatcatggatctgcaaatggaataaataccaaa ccaacacaggttctcaagggtatatcaccttattttggatattcaattgctggaaacatg gaccttgatcgaaattcctaccctgatgttgctgttggttccctctcagattcagtaact attttcagatcccggcctgtgattaatattcagaaaaccatcacagtaactcctaacaga attgacctccgccagaaaacagcgtgtggggcgcctagtgggatatgcctccaggttaaa tcctgttttgaatatactgctaaccccgctggttataatccttcaatatcaattgtgggc acacttgaagctgaaaaagaaagaagaaaatctgggctatcctcaagagttcagtttcga aaccaaggttctgagcccaaatatactcaagaactaactctgaagaggcagaaacagaaa gtgtgcatggaggaaaccctgtggctacaggataatatcagagataaactgcgtcccatt cccataactgcctcagtggagatccaagagccaagctctcgtaggcgagtgaattcactt ccagaagttcttccaattctgaattcagatgaacccaagacagctcatattgatgttcac ttcttaaaagagggatgtggagacgacaatgtatgtaacagcaaccttaaactagaatat aaattttgcacccgagaaggaaatcaagacaaattttcttatttaccaattcaaaaaggt gtaccagaactagttctaaaagatcagaaggatattgctttagaaataacagtgacaaac agcccttccaacccaaggaatcccacaaaagatggcgatgacgcccatgaggctaaactg attgcaacgtttccagacactttaacctattctgcatatagagaactgagggctttccct gagaaacagttgagttgtgttgccaaccagaatggctcgcaagctgactgtgagctcgga aatccttttaaaagaaattcaaatgtcactttttatttggttttaagtacaactgaagtc acctttgacaccccagatctggatattaatctgaagttagaaacaacaagcaatcaagat aatttggctccaattacagctaaagcaaaagtggttattgaactgcttttatcggtctcg ggagttgctaaaccttcccaggtgtattttggaggtacagttgttggcgagcaagctatg aaatctgaagatgaagtgggaagtttaatagagtatgaattcagggtaataaacttaggt aaacctcttacaaacctcggcacagcaaccttgaacattcagtggccaaaagaaattagc aatgggaaatggttgctttatttggtgaaagtagaatccaaaggattggaaaaggtaact tgtgagccacaaaaggagataaactccctgaacctaacggagtctcacaactcaagaaag aaacgggaaattactgaaaaacagatagatgataacagaaaattttctttatttgctgaa agaaaataccagactcttaactgtagcgtgaacgtgaactgtgtgaacatcagatgcccg ctgcgggggctggacagcaaggcgtctcttattttgcgctcgaggttatggaacagcaca tttctagaggaatattccaaactgaactacttggacattctcatgcgagccttcattgat gtgactgctgctgccgaaaatatcaggctgccaaatgcaggcactcaggttcgagtgact gtgtttccctcaaagactgtagctcagtattcgggagtaccttggtggatcatcctagtg gctattctcgctgggatcttgatgcttgctttattagtgtttatactatggaagtgtgga ttctttaaacgctctaggtacgatgacagtgttccccgataccatgctgtaaggatccgg aaagaagagcgagagatcaaagatgaaaagtatattgataaccttgaaaaaaaacagtgg atcacaaagtggaacgaaaatgaaagctactcatag

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