Homo sapiens (human): 383 Help Entry 383               CDS       T01001                                  Symbol ARG1 Name (RefSeq) arginase 1   KO K01476   arginase [EC:3.5.3.1] Organism hsa  Homo sapiens (human) Pathway hsa00220   Arginine biosynthesis hsa00330   Arginine and proline metabolism hsa01100   Metabolic pathways hsa01230   Biosynthesis of amino acids hsa05146   Amoebiasis Module hsa_M00029   Urea cycle hsa_M00134   Polyamine biosynthesis, arginine => ornithine => putrescine Network nt06010  Urea cycle   Element N00593   Urea cycle Disease H00186   Hyperargininemia H01398   Primary hyperammonemic disorders (Urea cycle disorders) Drug target Numidargistat:  D11792 Pegzilarginase:  D11695 Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09105 Amino acid metabolism    00220 Arginine biosynthesis     383 (ARG1)    00330 Arginine and proline metabolism     383 (ARG1)  09160 Human Diseases   09174 Infectious disease: parasitic    05146 Amoebiasis     383 (ARG1) Enzymes [BR:hsa01000]  3. Hydrolases   3.5  Acting on carbon-nitrogen bonds, other than peptide bonds    3.5.3  In linear amidines     3.5.3.1  arginase      383 (ARG1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Arginase Motif Other DBs NCBI-GeneID:  383 NCBI-ProteinID:  NP_000036 OMIM:  608313 HGNC:  663 Ensembl:  ENSG00000118520 Pharos:  P05089(Tchem) UniProt:  P05089 Structure PDB LinkDB All DBs Position 6:131573226..131584329 Genome browser AA seq 322 aa AA seqDB search MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPN DSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGV IWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLR DVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSF TPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAIT LACFGLAREGNHKPIDYLNPPK NT seq 969 nt NT seq  +upstreamnt  +downstreamnt atgagcgccaagtccagaaccatagggattattggagctcctttctcaaagggacagcca cgaggaggggtggaagaaggccctacagtattgagaaaggctggtctgcttgagaaactt aaagaacaagagtgtgatgtgaaggattatggggacctgccctttgctgacatccctaat gacagtccctttcaaattgtgaagaatccaaggtctgtgggaaaagcaagcgagcagctg gctggcaaggtggcagaagtcaagaagaacggaagaatcagcctggtgctgggcggagac cacagtttggcaattggaagcatctctggccatgccagggtccaccctgatcttggagtc atctgggtggatgctcacactgatatcaacactccactgacaaccacaagtggaaacttg catggacaacctgtatctttcctcctgaaggaactaaaaggaaagattcccgatgtgcca ggattctcctgggtgactccctgtatatctgccaaggatattgtgtatattggcttgaga gacgtggaccctggggaacactacattttgaaaactctaggcattaaatacttttcaatg actgaagtggacagactaggaattggcaaggtgatggaagaaacactcagctatctacta ggaagaaagaaaaggccaattcatctaagttttgatgttgacggactggacccatctttc acaccagctactggcacaccagtcgtgggaggtctgacatacagagaaggtctctacatc acagaagaaatctacaaaacagggctactctcaggattagatataatggaagtgaaccca tccctggggaagacaccagaagaagtaactcgaacagtgaacacagcagttgcaataacc ttggcttgtttcggacttgctcgggagggtaatcacaagcctattgactaccttaaccca cctaagtaa

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