Homo sapiens (human): 3938 Help Entry 3938              CDS       T01001                                  Symbol LCT, LAC, LPH, LPH1 Name (RefSeq) lactase   KO K01229   lactase-phlorizin hydrolase [EC:3.2.1.108 3.2.1.62] Organism hsa  Homo sapiens (human) Pathway hsa00052   Galactose metabolism hsa01100   Metabolic pathways hsa04973   Carbohydrate digestion and absorption Disease H00116   Congenital lactase deficiency Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09101 Carbohydrate metabolism    00052 Galactose metabolism     3938 (LCT)  09150 Organismal Systems   09154 Digestive system    04973 Carbohydrate digestion and absorption     3938 (LCT)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03110 Chaperones and folding catalysts [BR:hsa03110]     3938 (LCT) Enzymes [BR:hsa01000]  3. Hydrolases   3.2  Glycosylases    3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds     3.2.1.62  glycosylceramidase      3938 (LCT)     3.2.1.108  lactase      3938 (LCT) Chaperones and folding catalysts [BR:hsa03110]  Intramolecular chaperones   Others    3938 (LCT) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Glyco_hydro_1 Motif Other DBs NCBI-GeneID:  3938 NCBI-ProteinID:  NP_002290 OMIM:  603202 HGNC:  6530 Ensembl:  ENSG00000115850 UniProt:  P09848 LinkDB All DBs Position 2:complement(135787850..135837184) Genome browser AA seq 1927 aa AA seqDB search MELSWHVVFIALLSFSCWGSDWESDRNFISTAGPLTNDLLHNLSGLLGDQSSNFVAGDKD MYVCHQPLPTFLPEYFSSLHASQITHYKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKAL KTARLQPMVILHHQTLPASTLRRTEAFADLFADYATFAFHSFGDLVGIWFTFSDLEEVIK ELPHQESRASQLQTLSDAHRKAYEIYHESYAFQGGKLSVVLRAEDIPELLLEPPISALAQ DTVDFLSLDLSYECQNEASLRQKLSKLQTIEPKVKVFIFNLKLPDCPSTMKNPASLLFSL FEAINKDQVLTIGFDINEFLSCSSSSKKSMSCSLTGSLALQPDQQQDHETTDSSPASAYQ RIWEAFANQSRAERDAFLQDTFPEGFLWGASTGAFNVEGGWAEGGRGVSIWDPRRPLNTT EGQATLEVASDSYHKVASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKL IDRLQDAGIEPMATLFHWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTF HEPWVMSYAGYGTGQHPPGISDPGVASFKVAHLVLKAHARTWHHYNSHHRPQQQGHVGIV LNSDWAEPLSPERPEDLRASERFLHFMLGWFAHPVFVDGDYPATLRTQIQQMNRQCSHPV AQLPEFTEAEKQLLKGSADFLGLSHYTSRLISNAPQNTCIPSYDTIGGFSQHVNHVWPQT SSSWIRVVPWGIRRLLQFVSLEYTRGKVPIYLAGNGMPIGESENLFDDSLRVDYFNQYIN EVLKAIKEDSVDVRSYIARSLIDGFEGPSGYSQRFGLHHVNFSDSSKSRTPRKSAYFFTS IIEKNGFLTKGAKRLLPPNTVNLPSKVRAFTFPSEVPSKAKVVWEKFSSQPKFERDLFYH GTFRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLD ADLNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFH WDLPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFP PGVKDPGWAPYRIAHAVIKAHARVYHTYDEKYRQEQKGVISLSLSTHWAEPKSPGVPRDV EAADRMLQFSLGWFAHPIFRNGDYPDTMKWKVGNRSELQHLATSRLPSFTEEEKRFIRAT ADVFCLNTYYSRIVQHKTPRLNPPSYEDDQEMAEEEDPSWPSTAMNRAAPWGTRRLLNWI KEEYGDIPIYITENGVGLTNPNTEDTDRIFYHKTYINEALKAYRLDGIDLRGYVAWSLMD NFEWLNGYTVKFGLYHVDFNNTNRPRTARASARYYTEVITNNGMPLAREDEFLYGRFPEG FIWSAASAAYQIEGAWRADGKGLSIWDTFSHTPLRVENDAIGDVACDSYHKIAEDLVTLQ NLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWDLPQTL QDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAPGVSNRP GTAPYIVGHNLIKAHAEAWHLYNDVYRASQGGVISITISSDWAEPRDPSNQEDVEAARRY VQFMGGWFAHPIFKNGDYNEVMKTRIRDRSLAAGLNKSRLPEFTESEKRRINGTYDFFGF NHYTTVLAYNLNYATAISSFDADRGVASIADRSWPDSGSFWLKMTPFGFRRILNWLKEEY NDPPIYVTENGVSQREETDLNDTARIYYLRTYINEALKAVQDKVDLRGYTVWSAMDNFEW ATGFSERFGLHFVNYSDPSLPRIPKASAKFYASVVRCNGFPDPATGPHACLHQPDAGPTI SPVRQEEVQFLGLMLGTTEAQTALYVLFSLVLLGVCGLAFLSYKYCKRSKQGKTQRSQQE LSPVSSF NT seq 5784 nt NT seq  +upstreamnt  +downstreamnt atggagctgtcttggcatgtagtctttattgccctgctaagtttttcatgctgggggtca gactgggagtctgatagaaatttcatttccaccgctggtcctctaaccaatgacttgctg cacaacctgagtggtctcctgggagaccagagttctaactttgtagcaggggacaaagac atgtatgtttgtcaccagccactgcccactttcctgccagaatacttcagcagtctccat gccagtcagatcacccattataaggtatttctgtcatgggcacagctcctcccagcagga agcacccagaatccagacgagaaaacagtgcagtgctaccggcgactcctcaaggccctc aagactgcacggcttcagcccatggtcatcctgcaccaccagaccctccctgccagcacc ctccggagaaccgaagcctttgctgacctcttcgccgactatgccacattcgccttccac tccttcggggacctagttgggatctggttcaccttcagtgacttggaggaagtgatcaag gagcttccccaccaggaatcaagagcgtcacaactccagaccctcagtgatgcccacaga aaagcctatgagatttaccacgaaagctatgcttttcagggcggaaaactctctgttgtc ctgcgagctgaagatatcccggagctcctgctagaaccacccatatctgcgcttgcccag gacacggtcgatttcctctctcttgatttgtcttatgaatgccaaaatgaggcaagtctg cggcagaagctgagtaaattgcagaccattgagccaaaagtgaaagttttcatcttcaac ctaaaactcccagactgcccctccaccatgaagaacccagccagtctgctcttcagcctt tttgaagccataaataaagaccaagtgctcaccattgggtttgatattaatgagtttctg agttgttcatcaagttccaagaaaagcatgtcttgttctctgactggcagcctggccctt cagcctgaccagcagcaggaccacgagaccacggactcctctcctgcctctgcctatcag agaatctgggaagcatttgccaatcagtccagggcggaaagggatgccttcctgcaggat actttccctgaaggcttcctctggggtgcctccacaggagcctttaacgtggaaggaggc tgggccgagggtgggagaggggtgagcatctgggatccacgcaggcccctgaacaccact gagggccaagcgacgctggaggtggccagcgacagttaccacaaggtagcctctgacgtc gccctgctttgcggcctccgggctcaggtgtacaagttctccatctcctggtcccggatc ttccccatggggcacgggagcagccccagcctcccaggcgttgcctactacaacaagctg attgacaggctacaggatgcgggcatcgagcccatggccacgctgttccactgggacctg cctcaggccctgcaggatcatggtggatggcagaatgagagcgtggtggatgccttcctg gactatgcggccttctgcttctccacatttggggaccgtgtgaagctgtgggtgaccttc catgagccgtgggtgatgagctacgcaggctatggcaccggccagcaccctcccggcatc tctgacccaggagtggcctcttttaaggtggctcacttggtcctcaaggctcatgccaga acttggcaccactacaacagccatcatcgcccacagcagcaggggcacgtgggcattgtg ctgaactcagactgggcagaacccctgtctccagagaggcctgaggacctgagagcctct gagcgcttcttgcacttcatgctgggctggtttgcacaccccgtctttgtggatggagac tacccagccaccctgaggacccagatccaacagatgaacagacagtgctcccatcctgtg gctcaactccccgagttcacagaggcagagaagcagctcctgaaaggctctgctgatttt ctgggtctgtcgcattacacctcccgcctcatcagcaacgccccacaaaacacctgcatc cctagctatgataccattggaggcttctcccaacacgtgaaccatgtgtggccccagacc tcatcctcttggattcgtgtggtgccctgggggataaggaggctgttgcagtttgtatcc ctggaatacacaagaggaaaagttccaatataccttgccgggaatggcatgcccataggg gaaagtgaaaatctctttgatgattccttaagagtagactacttcaatcaatatatcaat gaggtgctcaaggctatcaaggaagactctgtggatgttcgttcctacattgctcgttcc ctcattgatggcttcgaaggcccttctggttacagccagcggtttggcctgcaccacgtc aacttcagcgacagcagcaagtcaaggactcccaggaaatctgcctactttttcactagc atcatagaaaagaacggtttcctcaccaagggggcaaaaagactgctaccacctaataca gtaaacctcccctccaaagtcagagccttcacttttccatctgaggtgccctccaaggct aaagtcgtttgggaaaagttctccagccaacccaagttcgaaagagatttgttctaccac gggacgtttcgggatgactttctgtggggcgtgtcctcttccgcttatcagattgaaggc gcgtgggatgccgatggcaaaggccccagcatctgggataactttacccacacaccaggg agcaatgtgaaagacaatgccactggagacatcgcctgtgacagctatcaccagctggat gccgatctgaatatgctccgagctttgaaggtgaaggcctaccgcttctctatctcctgg tctcggattttcccaactgggagaaacagctctatcaacagtcatggggttgattattac aacaggctgatcaatggcttggtggcaagcaacatctttcccatggtgacattgttccat tgggacctgccccaggccctccaggatatcggaggctgggagaatcctgccttgattgac ttgtttgacagctacgcagacttttgtttccagacctttggtgatagagtcaagttttgg atgacttttaatgagcccatgtacctggcatggctaggttatggctcaggggaatttccc ccaggggtgaaggacccaggctgggcaccatataggatagcccacgccgtcatcaaagcc catgccagagtctatcacacgtacgatgagaaatacaggcaggagcagaagggggtcatc tcgctgagcctcagtacacactgggcagagcccaagtcaccaggggtccccagagatgtg gaagccgctgaccgaatgctgcagttctccctgggctggtttgctcaccccatttttaga aacggagactatcctgacaccatgaagtggaaagtggggaacaggagtgaactgcagcac ttagccacctcccgcctgccaagcttcactgaggaagagaagaggttcatcagggcgacg gccgacgtcttctgcctcaacacgtactactccagaatcgtgcagcacaaaacacccagg ctaaacccaccctcctacgaagacgaccaggagatggctgaggaggaggacccttcgtgg ccttccacggcaatgaacagagctgcgccctgggggacgcgaaggctgctgaactggatc aaggaagagtatggtgacatccccatttacatcaccgaaaacggagtggggctgaccaat ccgaacacggaggatactgataggatattttaccacaaaacctacatcaatgaggctttg aaagcctacaggctcgatggtatagaccttcgagggtatgtcgcctggtctctgatggac aactttgagtggctaaatggctacacggtcaagtttggactgtaccatgttgatttcaac aacacgaacaggcctcgcacagcaagagcctccgccaggtactacacagaggtcattacc aacaacggcatgccactggccagggaggatgagtttctgtacggacggtttcctgagggc ttcatctggagtgcagcttctgctgcatatcagattgaaggtgcgtggagagcagatggc aaaggactcagcatttgggacacgttttctcacacaccactgagggttgagaacgatgcc attggagacgtggcctgtgacagttatcacaagattgctgaggatctggtcaccctgcag aacctgggcgtgtcccactaccgtttttccatctcctggtctcgcatcctccctgatgga accaccaggtacatcaatgaagcgggcctgaactactacgtgaggctcatcgatacactg ctggccgccagcatccagccccaggtgaccatttaccactgggacctaccacagacgctc caagatgtaggaggctgggagaatgagaccatcgtgcagcggtttaaggagtatgcagat gtgctcttccagaggctgggagacaaggtgaagttttggatcacgctgaatgagcccttt gtcattgcttaccagggctatggctacggaacagcagctccaggagtctccaataggcct ggcactgccccctacattgttggccacaatctaataaaggctcatgctgaggcctggcat ctgtacaacgatgtgtaccgcgccagtcaaggtggcgtgatttccatcaccatcagcagt gactgggctgaacccagagatccctctaaccaggaggatgtggaggcagccaggagatat gttcagttcatgggaggctggtttgcacatcctattttcaagaatggagattacaatgag gtgatgaagacgcggatccgtgacaggagcttggctgcaggcctcaacaagtctcggctg ccagaatttacagagagtgagaagaggaggatcaacggcacctatgacttttttgggttc aatcactacaccactgtcctcgcctacaacctcaactatgccactgccatctcttctttt gatgcagacagaggagttgcttccatcgcagatcgctcgtggccagactctggctccttc tggctgaagatgacgccttttggcttcaggaggatcctgaactggttaaaggaggaatac aatgaccctccaatttatgtcacagagaatggagtgtcccagcgggaagaaacagacctc aatgacactgcaaggatctactaccttcggacttacatcaatgaggccctcaaagctgtg caggacaaggtggaccttcgaggatacacagtttggagtgcgatggacaattttgagtgg gccacaggcttttcagagagatttggtctgcattttgtgaactacagtgacccttctctg ccaaggatccccaaagcatcagcgaagttctacgcctctgtggtccgatgcaatggcttc cctgaccccgctacagggcctcacgcttgtctccaccagccagatgctggacccaccatc agccccgtgagacaggaggaggtgcagttcctggggctaatgctcggcaccacagaagca cagacagctttgtacgttctcttttctcttgtgcttcttggagtctgtggcttggcattt ctgtcatacaagtactgcaagcgctctaagcaagggaaaacacaacgaagccaacaggaa ttgagcccggtgtcttcattctga

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