Homo sapiens (human): 408 Help Entry 408               CDS       T01001                                  Symbol ARRB1, ARB1, ARR1 Name (RefSeq) arrestin beta 1   KO K04439   beta-arrestin Organism hsa  Homo sapiens (human) Pathway hsa04010   MAPK signaling pathway hsa04062   Chemokine signaling pathway hsa04144   Endocytosis hsa04340   Hedgehog signaling pathway hsa04728   Dopaminergic synapse hsa04740   Olfactory transduction hsa04926   Relaxin signaling pathway hsa04928   Parathyroid hormone synthesis, secretion and action hsa04929   GnRH secretion hsa05032   Morphine addiction hsa05207   Chemical carcinogenesis - receptor activation Network nt06230  Cell cycle (cancer)   Element N01336   CHRNA7-E2F signaling pathway N01337   NNK/NNN to CHRNA7-E2F signaling pathway Drug target Oliceridine:  D11214<US> Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     408 (ARRB1)  09150 Organismal Systems   09151 Immune system    04062 Chemokine signaling pathway     408 (ARRB1)   09152 Endocrine system    04929 GnRH secretion     408 (ARRB1)    04926 Relaxin signaling pathway     408 (ARRB1)    04928 Parathyroid hormone synthesis, secretion and action     408 (ARRB1)   09156 Nervous system    04728 Dopaminergic synapse     408 (ARRB1)   09157 Sensory system    04740 Olfactory transduction     408 (ARRB1)  09160 Human Diseases   09161 Cancer: overview    05207 Chemical carcinogenesis - receptor activation     408 (ARRB1)   09165 Substance dependence    05032 Morphine addiction     408 (ARRB1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hsa04131]     408 (ARRB1) Membrane trafficking [BR:hsa04131]  Endocytosis   Clathrin-mediated endocytosis    GPCR adaptor proteins     408 (ARRB1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Arrestin_N Arrestin_C LDB19 VPS28 AP3B1_C Motif Other DBs NCBI-GeneID:  408 NCBI-ProteinID:  NP_004032 OMIM:  107940 HGNC:  711 Ensembl:  ENSG00000137486 UniProt:  P49407 B7Z1Q3 Structure PDBPDBj LinkDB All DBs Position 11:complement(75260122..75351661) Genome browser AA seq 418 aa AA seqDB search MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCA FRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIP PNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGP QPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHVTNNTNKTVKKIKISVRQYAD ICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNL ASSTLLREGANREILGIIVSYKVKVKLVVSRGGLLGDLASSDVAVELPFTLMHPKPKEEP PHREVPENETPVDTNLIELDTNDDDIVFEDFARQRLKGMKDDKEEEEDGTGSPQLNNR NT seq 1257 nt NT seq  +upstreamnt  +downstreamnt atgggcgacaaagggacccgagtgttcaagaaggccagtccaaatggaaagctcaccgtc tacctgggaaagcgggactttgtggaccacatcgacctcgtggaccctgtggatggtgtg gtcctggtggatcctgagtatctcaaagagcggagagtctatgtgacgctgacctgcgcc ttccgctatggccgggaggacctggatgtcctgggcctgacctttcgcaaggacctgttt gtggccaacgtacagtcgttcccaccggcccccgaggacaagaagcccctgacgcggctg caggaacgcctcatcaagaagctgggcgagcacgcttaccctttcacctttgagatccct ccaaaccttccatgttctgtgacactgcagccggggcccgaagacacggggaaggcttgc ggtgtggactatgaagtcaaagccttctgcgcggagaatttggaggagaagatccacaag cggaattctgtgcgtctggtcatccggaaggttcagtatgccccagagaggcctggcccc cagcccacagccgagaccaccaggcagttcctcatgtcggacaagcccttgcacctagaa gcctctctggataaggagatctattaccatggagaacccatcagcgtcaacgtccacgtc accaacaacaccaacaagacggtgaagaagatcaagatctcagtgcgccagtatgcagac atctgccttttcaacacagctcagtacaagtgccctgttgccatggaagaggctgatgac actgtggcacccagctcgacgttctgcaaggtctacacactgacccccttcctagccaat aaccgagagaagcggggcctcgccttggacgggaagctcaagcacgaagacacgaacttg gcctctagcaccctgttgagggaaggtgccaaccgtgagatcctggggatcattgtttcc tacaaagtgaaagtgaagctggtggtgtctcggggcggcctgttgggagatcttgcatcc agcgacgtggccgtggaactgcccttcaccctaatgcaccccaagcccaaagaggaaccc ccgcatcgggaagttccagagaacgagacgccagtagataccaatctcatagaacttgac acaaatgatgacgacattgtatttgaggactttgctcgccagagactgaaaggcatgaag gatgacaaggaggaagaggaggatggtaccggctctccacagctcaacaacagatag

Homo sapiens (human): 409 Help Entry 409               CDS       T01001                                  Symbol ARRB2, ARB2, ARR2, BARR2 Name (RefSeq) arrestin beta 2   KO K04439   beta-arrestin Organism hsa  Homo sapiens (human) Pathway hsa04010   MAPK signaling pathway hsa04062   Chemokine signaling pathway hsa04144   Endocytosis hsa04340   Hedgehog signaling pathway hsa04728   Dopaminergic synapse hsa04740   Olfactory transduction hsa04926   Relaxin signaling pathway hsa04928   Parathyroid hormone synthesis, secretion and action hsa04929   GnRH secretion hsa05032   Morphine addiction hsa05207   Chemical carcinogenesis - receptor activation Drug target Oliceridine:  D11214<US> Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     409 (ARRB2)  09150 Organismal Systems   09151 Immune system    04062 Chemokine signaling pathway     409 (ARRB2)   09152 Endocrine system    04929 GnRH secretion     409 (ARRB2)    04926 Relaxin signaling pathway     409 (ARRB2)    04928 Parathyroid hormone synthesis, secretion and action     409 (ARRB2)   09156 Nervous system    04728 Dopaminergic synapse     409 (ARRB2)   09157 Sensory system    04740 Olfactory transduction     409 (ARRB2)  09160 Human Diseases   09161 Cancer: overview    05207 Chemical carcinogenesis - receptor activation     409 (ARRB2)   09165 Substance dependence    05032 Morphine addiction     409 (ARRB2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hsa04131]     409 (ARRB2) Membrane trafficking [BR:hsa04131]  Endocytosis   Clathrin-mediated endocytosis    GPCR adaptor proteins     409 (ARRB2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Arrestin_N Arrestin_C SCA7 Motif Other DBs NCBI-GeneID:  409 NCBI-ProteinID:  NP_004304 OMIM:  107941 HGNC:  712 Ensembl:  ENSG00000141480 UniProt:  P32121 LinkDB All DBs Position 17:4710632..4721497 Genome browser AA seq 409 aa AA seqDB search MGEKPGTRVFKKSSPNCKLTVYLGKRDFVDHLDKVDPVDGVVLVDPDYLKDRKVFVTLTC AFRYGREDLDVLGLSFRKDLFIATYQAFPPVPNPPRPPTRLQDRLLRKLGQHAHPFFFTI PQNLPCSVTLQPGPEDTGKACGVDFEIRAFCAKSLEEKSHKRNSVRLVIRKVQFAPEKPG PQPSAETTRHFLMSDRSLHLEASLDKELYYHGEPLNVNVHVTNNSTKTVKKIKVSVRQYA DICLFSTAQYKCPVAQLEQDDQVSPSSTFCKVYTITPLLSDNREKRGLALDGKLKHEDTN LASSTIVKEGANKEVLGILVSYRVKVKLVVSRGGDVSVELPFVLMHPKPHDHIPLPRPQS AAPETDVPVDTNLIEFDTNYATDDDIVFEDFARLRLKGMKDDDYDDQLC NT seq 1230 nt NT seq  +upstreamnt  +downstreamnt atgggggagaaacccgggaccagggtcttcaagaagtcgagccctaactgcaagctcacc gtgtacttgggcaagcgggacttcgtagatcacctggacaaagtggaccctgtagatggc gtggtgcttgtggaccctgactacctgaaggaccgcaaagtgtttgtgaccctcacctgc gccttccgctatggccgtgaagacctggatgtgctgggcttgtccttccgcaaagacctg ttcatcgccacctaccaggccttccccccggtgcccaacccaccccggccccccacccgc ctgcaggaccggctgctgaggaagctgggccagcatgcccaccccttcttcttcaccata ccccagaatcttccatgctccgtcacactgcagccaggcccagaggatacaggaaaggcc tgcggcgtagactttgagattcgagccttctgtgctaaatcactagaagagaaaagccac aaaaggaactctgtgcggctggtgatccgaaaggtgcagttcgccccggagaaacccggc ccccagccttcagccgaaaccacacgccacttcctcatgtctgaccggtccctgcacctc gaggcttccctggacaaggagctgtactaccatggggagcccctcaatgtaaatgtccac gtcaccaacaactccaccaagaccgtcaagaagatcaaagtctctgtgagacagtacgcc gacatctgcctcttcagcaccgcccagtacaagtgtcctgtggctcaactcgaacaagat gaccaggtatctcccagctccacattctgtaaggtgtacaccataaccccactgctcagc gacaaccgggagaagcggggtctcgccctggatgggaaactcaagcacgaggacaccaac ctggcttccagcaccatcgtgaaggagggtgccaacaaggaggtgctgggaatcctggtg tcctacagggtcaaggtgaagctggtggtgtctcgaggcggggatgtctctgtggagctg ccttttgttcttatgcaccccaagccccacgaccacatccccctccccagaccccagtca gccgctccggagacagatgtccctgtggacaccaacctcattgaatttgataccaactat gccacagatgatgacattgtgtttgaggactttgcccggcttcggctgaaggggatgaag gatgacgactatgatgatcaactctgctag

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