Homo sapiens (human): 4953 Help Entry 4953              CDS       T01001                                  Symbol ODC1, BABS, NEDBA, NEDBIA, ODC Name (RefSeq) ornithine decarboxylase 1   KO K01581   ornithine decarboxylase [EC:4.1.1.17] Organism hsa  Homo sapiens (human) Pathway hsa00330   Arginine and proline metabolism hsa00480   Glutathione metabolism hsa01100   Metabolic pathways Module hsa_M00134   Polyamine biosynthesis, arginine => ornithine => putrescine Disease H02470   Neurodevelopmental disorder with structural brain abnormalities Drug target Eflornithine (DG00440):  D00829<US> D07883 Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09105 Amino acid metabolism    00330 Arginine and proline metabolism     4953 (ODC1)   09106 Metabolism of other amino acids    00480 Glutathione metabolism     4953 (ODC1) Enzymes [BR:hsa01000]  4. Lyases   4.1  Carbon-carbon lyases    4.1.1  Carboxy-lyases     4.1.1.17  ornithine decarboxylase      4953 (ODC1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Orn_Arg_deC_N Orn_DAP_Arg_deC AP_endonuc_2 Motif Other DBs NCBI-GeneID:  4953 NCBI-ProteinID:  NP_001274118 OMIM:  165640 HGNC:  8109 Ensembl:  ENSG00000115758 Vega:  OTTHUMG00000090450 Pharos:  P11926(Tclin) UniProt:  P11926 Structure PDB LinkDB All DBs Position 2:complement(10439968..10448327) Genome browser AA seq 461 aa AA seqDB search MNNFGNEEFDCHFLDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDILKKHLRWLKALP RVTPFYAVKCNDSKAIVKTLAATGTGFDCASKTEIQLVQSLGVPPERIIYANPCKQVSQI KYAANNGVQMMTFDSEVELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLRTSRLL LERAKELNIDVVGVSFHVGSGCTDPETFVQAISDARCVFDMGAEVGFSMYLLDIGGGFPG SEDVKLKFEEITGVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKIVLKEQ TGSDDEDESSEQTFMYYVNDGVYGSFNCILYDHAHVKPLLQKRPKPDEKYYSSSIWGPTC DGLDRIVERCDLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPTIYYVMSGPAWQLMQQF QNPDFPPEVEEQDASTLPVSCAWESGMKRHRAACASASINV NT seq 1386 nt NT seq  +upstreamnt  +downstreamnt atgaacaactttggtaatgaagagtttgactgccacttcctcgatgaaggttttactgcc aaggacattctggaccagaaaattaatgaagtttcttcttctgatgataaggatgccttc tatgtggcagacctgggagacattctaaagaaacatctgaggtggttaaaagctctccct cgtgtcacccccttttatgcagtcaaatgtaatgatagcaaagccatcgtgaagaccctt gctgctaccgggacaggatttgactgtgctagcaagactgaaatacagttggtgcagagt ctgggggtgcctccagagaggattatctatgcaaatccttgtaaacaagtatctcaaatt aagtatgctgctaataatggagtccagatgatgacttttgatagtgaagttgagttgatg aaagttgccagagcacatcccaaagcaaagttggttttgcggattgccactgatgattcc aaagcagtctgtcgtctcagtgtgaaattcggtgccacgctcagaaccagcaggctcctt ttggaacgggcgaaagagctaaatatcgatgttgttggtgtcagcttccatgtaggaagc ggctgtaccgatcctgagaccttcgtgcaggcaatctctgatgcccgctgtgtttttgac atgggggctgaggttggtttcagcatgtatctgcttgatattggcggtggctttcctgga tctgaggatgtgaaacttaaatttgaagagatcaccggcgtaatcaacccagcgttggac aaatactttccgtcagactctggagtgagaatcatagctgagcccggcagatactatgtt gcatcagctttcacgcttgcagttaatatcattgccaagaaaattgtattaaaggaacag acgggctctgatgacgaagatgagtcgagtgagcagacctttatgtattatgtgaatgat ggcgtctatggatcatttaattgcatactctatgaccacgcacatgtaaagccccttctg caaaagagacctaaaccagatgagaagtattattcatccagcatatggggaccaacatgt gatggcctcgatcggattgttgagcgctgtgacctgcctgaaatgcatgtgggtgattgg atgctctttgaaaacatgggcgcttacactgttgctgctgcctctacgttcaatggcttc cagaggccgacgatctactatgtgatgtcagggcctgcgtggcaactcatgcagcaattc cagaaccccgacttcccacccgaagtagaggaacaggatgccagcaccctgcctgtgtct tgtgcctgggagagtgggatgaaacgccacagagcagcctgtgcttcggctagtattaat gtgtag

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