Homo sapiens (human): 4953
Help
Entry
4953 CDS
T01001
Symbol
ODC1, BABS, NEDBA, NEDBIA, ODC
Name
(RefSeq) ornithine decarboxylase 1
KO
K01581
ornithine decarboxylase [EC:
4.1.1.17
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00330
Arginine and proline metabolism
hsa00480
Glutathione metabolism
hsa01100
Metabolic pathways
hsa04148
Efferocytosis
Module
hsa_M00134
Polyamine biosynthesis, arginine => ornithine => putrescine
Network
nt06033
Glycine, serine and arginine metabolism
nt06535
Efferocytosis
Element
N01623
Spermine biosynthesis
N01779
Continual efferocytosis enhanced by the AC-derived arginine and ornithine
Disease
H02470
Neurodevelopmental disorder with structural brain abnormalities
Drug target
Eflornithine (
DG00440
):
D00829
<US>
D07883
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09105 Amino acid metabolism
00330 Arginine and proline metabolism
4953 (ODC1)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
4953 (ODC1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
4953 (ODC1)
Enzymes [BR:
hsa01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.17 ornithine decarboxylase
4953 (ODC1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Orn_Arg_deC_N
Orn_DAP_Arg_deC
AP_endonuc_2
Motif
Other DBs
NCBI-GeneID:
4953
NCBI-ProteinID:
NP_001274118
OMIM:
165640
HGNC:
8109
Ensembl:
ENSG00000115758
Pharos:
P11926
(Tclin)
UniProt:
P11926
Structure
PDB
PDBj
LinkDB
All DBs
Position
2:complement(10439968..10448327)
Genome browser
AA seq
461 aa
AA seq
DB search
MNNFGNEEFDCHFLDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDILKKHLRWLKALP
RVTPFYAVKCNDSKAIVKTLAATGTGFDCASKTEIQLVQSLGVPPERIIYANPCKQVSQI
KYAANNGVQMMTFDSEVELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLRTSRLL
LERAKELNIDVVGVSFHVGSGCTDPETFVQAISDARCVFDMGAEVGFSMYLLDIGGGFPG
SEDVKLKFEEITGVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKIVLKEQ
TGSDDEDESSEQTFMYYVNDGVYGSFNCILYDHAHVKPLLQKRPKPDEKYYSSSIWGPTC
DGLDRIVERCDLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPTIYYVMSGPAWQLMQQF
QNPDFPPEVEEQDASTLPVSCAWESGMKRHRAACASASINV
NT seq
1386 nt
NT seq
+upstream
nt +downstream
nt
atgaacaactttggtaatgaagagtttgactgccacttcctcgatgaaggttttactgcc
aaggacattctggaccagaaaattaatgaagtttcttcttctgatgataaggatgccttc
tatgtggcagacctgggagacattctaaagaaacatctgaggtggttaaaagctctccct
cgtgtcacccccttttatgcagtcaaatgtaatgatagcaaagccatcgtgaagaccctt
gctgctaccgggacaggatttgactgtgctagcaagactgaaatacagttggtgcagagt
ctgggggtgcctccagagaggattatctatgcaaatccttgtaaacaagtatctcaaatt
aagtatgctgctaataatggagtccagatgatgacttttgatagtgaagttgagttgatg
aaagttgccagagcacatcccaaagcaaagttggttttgcggattgccactgatgattcc
aaagcagtctgtcgtctcagtgtgaaattcggtgccacgctcagaaccagcaggctcctt
ttggaacgggcgaaagagctaaatatcgatgttgttggtgtcagcttccatgtaggaagc
ggctgtaccgatcctgagaccttcgtgcaggcaatctctgatgcccgctgtgtttttgac
atgggggctgaggttggtttcagcatgtatctgcttgatattggcggtggctttcctgga
tctgaggatgtgaaacttaaatttgaagagatcaccggcgtaatcaacccagcgttggac
aaatactttccgtcagactctggagtgagaatcatagctgagcccggcagatactatgtt
gcatcagctttcacgcttgcagttaatatcattgccaagaaaattgtattaaaggaacag
acgggctctgatgacgaagatgagtcgagtgagcagacctttatgtattatgtgaatgat
ggcgtctatggatcatttaattgcatactctatgaccacgcacatgtaaagccccttctg
caaaagagacctaaaccagatgagaagtattattcatccagcatatggggaccaacatgt
gatggcctcgatcggattgttgagcgctgtgacctgcctgaaatgcatgtgggtgattgg
atgctctttgaaaacatgggcgcttacactgttgctgctgcctctacgttcaatggcttc
cagaggccgacgatctactatgtgatgtcagggcctgcgtggcaactcatgcagcaattc
cagaaccccgacttcccacccgaagtagaggaacaggatgccagcaccctgcctgtgtct
tgtgcctgggagagtgggatgaaacgccacagagcagcctgtgcttcggctagtattaat
gtgtag
DBGET
integrated database retrieval system
