Homo sapiens (human): 4968 Help Entry 4968              CDS       T01001                                  Symbol OGG1, HMMH, HOGG1, MUTM, OGH1 Name (RefSeq) 8-oxoguanine DNA glycosylase   KO K03660   N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18] Organism hsa  Homo sapiens (human) Pathway hsa03410   Base excision repair Network nt06504  Base excision repair   Element N01434   Base excision and strand cleavage by bifunctional glycosylase Disease H00021   Renal cell carcinoma Brite KEGG Orthology (KO) [BR:hsa00001]  09120 Genetic Information Processing   09124 Replication and repair    03410 Base excision repair     4968 (OGG1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03400 DNA repair and recombination proteins [BR:hsa03400]     4968 (OGG1) Enzymes [BR:hsa01000]  4. Lyases   4.2  Carbon-oxygen lyases    4.2.99  Other carbon-oxygen lyases     4.2.99.18  DNA-(apurinic or apyrimidinic site) lyase      4968 (OGG1) DNA repair and recombination proteins [BR:hsa03400]  Eukaryotic type   SSBR (single strand breaks repair)    BER (base exicision repair)     DNA glycosylases      4968 (OGG1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  OGG_N HhH-GPD HHH RecR_HhH Motif Other DBs NCBI-GeneID:  4968 NCBI-ProteinID:  NP_002533 OMIM:  601982 HGNC:  8125 Ensembl:  ENSG00000114026 UniProt:  O15527 E5KPN1 Structure PDBPDBj LinkDB All DBs Position 3:9749952..9783108 Genome browser AA seq 345 aa AA seqDB search MPARALLPRRMGHRTLASTPALWASIPCPRSELRLDLVLPSGQSFRWREQSPAHWSGVLA DQVWTLTQTEEQLHCTVYRGDKSQASRPTPDELEAVRKYFQLDVTLAQLYHHWGSVDSHF QEVAQKFQGVRLLRQDPIECLFSFICSSNNNIARITGMVERLCQAFGPRLIQLDDVTYHG FPSLQALAGPEVEAHLRKLGLGYRARYVSASARAILEEQGGLAWLQQLRESSYEEAHKAL CILPGVGTKVADCICLMALDKPQAVPVDVHMWHIAQRDYSWHPTTSQAKGPSPQTNKELG NFFRSLWGPYAGWAQAVLFSADLRQSRHAQEPPAKRRKGSKGPEG NT seq 1038 nt NT seq  +upstreamnt  +downstreamnt atgcctgcccgcgcgcttctgcccaggcgcatggggcatcgtactctagcctccactcct gccctgtgggcctccatcccgtgccctcgctctgagctgcgcctggacctggttctgcct tctggacaatctttccggtggagggagcaaagtcctgcacactggagtggtgtactagcg gatcaagtatggacactgactcagactgaggagcagctccactgcactgtgtaccgagga gacaagagccaggctagcaggcccacaccagacgagctggaggccgtgcgcaagtacttc cagctagatgttaccctggctcaactgtatcaccactggggttccgtggactcccacttc caagaggtggctcagaaattccaaggtgtgcgactgctgcgacaagaccccatcgaatgc cttttctcttttatctgttcctccaacaacaacatcgcccgcatcactggcatggtggag cggctgtgccaggcttttggacctcggctcatccagcttgatgatgtcacctaccatggc ttccccagcctgcaggccctggctgggccagaggtggaggctcatctcaggaagctgggc ctgggctatcgtgcccgttacgtgagtgccagtgcccgagccatcctggaagaacagggc gggctagcctggctgcagcagctacgagagtcctcatatgaggaggcccacaaggccctc tgcatcctgcctggagtgggcaccaaggtggctgactgcatctgcctgatggccctagac aagccccaggctgtgcccgtggatgtccatatgtggcacattgcccaacgtgactacagc tggcaccctaccacgtcccaggcgaagggaccgagcccccagaccaacaaggaactggga aactttttccggagcctgtggggaccttatgctggctgggcccaagcggtgctgttcagt gccgacctgcgccaatcccgccatgctcaggagccaccagcaaagcgcagaaagggttcc aaagggccggaaggctag

Homo sapiens (human): 4913 Help Entry 4913              CDS       T01001                                  Symbol NTHL1, FAP3, NTH1, OCTS3, hNTH1 Name (RefSeq) nth like DNA glycosylase 1   KO K10773   endonuclease III [EC:3.2.2.- 4.2.99.18] Organism hsa  Homo sapiens (human) Pathway hsa03410   Base excision repair Network nt06504  Base excision repair   Element N01434   Base excision and strand cleavage by bifunctional glycosylase Disease H01025   Familial adenomatous polyposis Brite KEGG Orthology (KO) [BR:hsa00001]  09120 Genetic Information Processing   09124 Replication and repair    03410 Base excision repair     4913 (NTHL1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03400 DNA repair and recombination proteins [BR:hsa03400]     4913 (NTHL1) Enzymes [BR:hsa01000]  4. Lyases   4.2  Carbon-oxygen lyases    4.2.99  Other carbon-oxygen lyases     4.2.99.18  DNA-(apurinic or apyrimidinic site) lyase      4913 (NTHL1) DNA repair and recombination proteins [BR:hsa03400]  Eukaryotic type   SSBR (single strand breaks repair)    BER (base exicision repair)     DNA glycosylases      4913 (NTHL1)  Prokaryotic type      4913 (NTHL1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  HhH-GPD HHH RecR_HhH HHH_5 Motif Other DBs NCBI-GeneID:  4913 NCBI-ProteinID:  NP_002519 OMIM:  602656 HGNC:  8028 Ensembl:  ENSG00000065057 UniProt:  P78549 E5KTI5 Structure PDBPDBj LinkDB All DBs Position 16:complement(2039820..2047834) Genome browser AA seq 304 aa AA seqDB search MTALSARMLTRSRSLGPGAGPRGCREEPGPLRRREAAAEARKSHSPVKRPRKAQRLRVAY EGSDSEKGEGAEPLKVPVWEPQDWQQQLVNIRAMRNKKDAPVDHLGTEHCYDSSAPPKVR RYQVLLSLMLSSQTKDQVTAGAMQRLRARGLTVDSILQTDDATLGKLIYPVGFWRSKVKY IKQTSAILQQHYGGDIPASVAELVALPGVGPKMAHLAMAVAWGTVSGIAVDTHVHRIANR LRWTKKATKSPEETRAALEEWLPRELWHEINGLLVGFGQQTCLPVHPRCHACLNQALCPA AQGL NT seq 915 nt NT seq  +upstreamnt  +downstreamnt atgaccgccttgagcgcgaggatgctgacccggagccggagcctgggacccggggctggg ccgcgggggtgtagggaggagcccgggcctctccggagaagagaggctgcagcagaagcg aggaaaagccacagccccgtgaagcgtccgcggaaagcacagagactgcgtgtggcctat gagggctcggacagtgagaaaggtgagggggctgagcccctcaaggtgccagtctgggag ccccaggactggcagcaacagctggtcaacatccgtgccatgaggaacaaaaaggatgca cctgtggaccatctggggactgagcactgctatgactccagtgcccccccaaaggtacgc aggtaccaggtgctgctgtcactgatgctctccagccaaaccaaagaccaggtgacggcg ggcgccatgcagcgactgcgggcgcggggcctgacggtggacagcatcctgcagacagat gatgccacgctgggcaagctcatctaccccgtcggtttctggaggagcaaggtgaaatac atcaagcagaccagcgccatcctgcagcagcactacggtggggacatcccagcctctgtg gccgagctggtggcgctgccgggtgttgggcccaagatggcacacctggctatggctgtg gcctggggcactgtgtcaggcattgcagtggacacgcatgtgcacagaatcgccaacagg ctgaggtggaccaagaaggcaaccaagtccccagaggagacccgcgccgccctggaggag tggctgcctagggagctgtggcacgagatcaatggactcttggtgggcttcggccagcag acctgtctgcctgtgcaccctcgctgccacgcctgcctcaaccaagccctctgcccggcc gcccagggtctctga

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