| Entry |
|
|---|
| Name |
Base excision and strand cleavage by bifunctional glycosylase
|
|---|
| Definition |
glycosylase -> APEX == POLB+XRCC1 == PARP,PARG,ADPRS |
|---|
| Expanded |
4968,4913 -> 328 == 5423+7515 == 142,10038,8505,54936 |
|---|
| Class |
|
|---|
| Type |
Reference
|
|---|
| Pathway |
|
|---|
| Gene |
| 4968 | OGG1; 8-oxoguanine DNA glycosylase |
| 4913 | NTHL1; nth like DNA glycosylase 1 |
| 328 | APEX1; apurinic/apyrimidinic endodeoxyribonuclease 1 |
| 5423 | POLB; DNA polymerase beta |
| 7515 | XRCC1; X-ray repair cross complementing 1 |
| 142 | PARP1; poly(ADP-ribose) polymerase 1 |
| 10038 | PARP2; poly(ADP-ribose) polymerase 2 |
| 8505 | PARG; poly(ADP-ribose) glycohydrolase |
| 54936 | ADPRS; ADP-ribosylserine hydrolase |
|
|---|
| Reference |
|
|---|
| Authors |
Grundy GJ, Parsons JL |
|---|
| Title |
Base excision repair and its implications to cancer therapy. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Robertson AB, Klungland A, Rognes T, Leiros I |
|---|
| Title |
DNA repair in mammalian cells: Base excision repair: the long and short of it. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Hegde ML, Hazra TK, Mitra S |
|---|
| Title |
Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells. |
|---|
| Journal |
|
|---|
| LinkDB |
|
|---|
