KEGG Orthology (KO) [BR:ko00001]
09120 Genetic Information Processing
09124 Replication and repair
03410 Base excision repair
K10773 NTHL1, nth; endonuclease III
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03400 DNA repair and recombination proteins
K10773 NTHL1, nth; endonuclease III
Enzymes [BR:ko01000]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.99 Other carbon-oxygen lyases
4.2.99.18 DNA-(apurinic or apyrimidinic site) lyase
K10773 NTHL1, nth; endonuclease III
DNA repair and recombination proteins [BR:ko03400]
Eukaryotic type
SSBR (single strand breaks repair)
BER (base exicision repair)
DNA glycosylases
K10773 NTHL1, nth; endonuclease III
Prokaryotic type
SSBR (single strand breaks repair)
BER (base exicision repair)
DNA glycosylases
K10773 NTHL1, nth; endonuclease III
Ikeda S, Biswas T, Roy R, Izumi T, Boldogh I, Kurosky A, Sarker AH, Seki S, Mitra S
Title
Purification and characterization of human NTH1, a homolog of Escherichia coli endonuclease III. Direct identification of Lys-212 as the active nucleophilic residue.
Cell-cycle regulation, intracellular sorting and induced overexpression of the human NTH1 DNA glycosylase involved in removal of formamidopyrimidine residues from DNA.