Homo sapiens (human): 51684
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Entry
51684 CDS
T01001
Symbol
SUFU, BCNS2, JBTS32, PRO1280, SUFUH, SUFUXL
Name
(RefSeq) SUFU negative regulator of hedgehog signaling
KO
K06229
suppressor of fused
Organism
hsa
Homo sapiens (human)
Pathway
hsa04340
Hedgehog signaling pathway
hsa05200
Pathways in cancer
hsa05217
Basal cell carcinoma
Network
nt06217
HH signaling (cancer)
nt06269
Basal cell carcinoma
nt06501
HH signaling
Element
N00010
Mutation-inactivated PTCH1 to Hedgehog signaling pathway
N00017
Mutation-activated SMO to Hedgehog signaling pathway
N00062
Hedgehog signaling pathway
Disease
H00530
Joubert syndrome and related disorders
H00895
Basal cell nevus syndrome
H01556
Meningioma
H01667
Medulloblastoma
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04340 Hedgehog signaling pathway
51684 (SUFU)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
51684 (SUFU)
09162 Cancer: specific types
05217 Basal cell carcinoma
51684 (SUFU)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
03037 Cilium and associated proteins [BR:
hsa03037
]
51684 (SUFU)
Cilium and associated proteins [BR:
hsa03037
]
Primary cilia and associated proteins
Other primary cilia associated proteins
51684 (SUFU)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SUFU_C
SUFU
Motif
Other DBs
NCBI-GeneID:
51684
NCBI-ProteinID:
NP_057253
OMIM:
607035
HGNC:
16466
Ensembl:
ENSG00000107882
Pharos:
Q9UMX1
(Tbio)
UniProt:
Q9UMX1
Structure
PDB
PDBj
LinkDB
All DBs
Position
10:102502819..102633535
Genome browser
AA seq
484 aa
AA seq
DB search
MAELRPSGAPGPTAPPAPGPTAPPAFASLFPPGLHAIYGECRRLYPDQPNPLQVTAIVKY
WLGGPDPLDYVSMYRNVGSPSANIPEHWHYISFGLSDLYGDNRVHEFTGTDGPSGFGFEL
TFRLKRETGESAPPTWPAELMQGLARYVFQSENTFCSGDHVSWHSPLDNSESRIQHMLLT
EDPQMQPVQTPFGVVTFLQIVGVCTEELHSAQQWNGQGILELLRTVPIAGGPWLITDMRR
GETIFEIDPHLQERVDKGIETDGSNLSGVSAKCAWDDLSRPPEDDEDSRSICIGTQPRRL
SGKDTEQIRETLRRGLEINSKPVLPPINPQRQNGLAHDRAPSRKDSLESDSSTAIIPHEL
IRTRQLESVHLKFNQESGALIPLCLRGRLLHGRHFTYKSITGDMAITFVSTGVEGAFATE
EHPYAAHGPWLQILLTEEFVEKMLEDLEDLTSPEEFKLPKEYSWPEKKLKVSILPDVVFD
SPLH
NT seq
1455 nt
NT seq
+upstream
nt +downstream
nt
atggcggagctgcggcctagcggcgcccccggccccaccgcgcccccggcccctggcccg
actgcccccccggccttcgcttcgctctttcccccgggactgcacgccatctacggagag
tgccgccgcctttaccctgaccagccgaacccgctccaggttaccgctatcgtcaagtac
tggttgggtggcccagaccccttggactatgttagcatgtacaggaatgtggggagccct
tctgctaacatccccgagcactggcactacatcagcttcggcctgagtgatctctatggt
gacaacagagtccatgagtttacaggaacagatggacctagtggttttggctttgagttg
acctttcgtctgaagagagaaactggggagtctgccccaccaacatggcccgcagagtta
atgcagggcttggcacgatacgtgttccagtcagagaacaccttctgcagtggggaccat
gtgtcctggcacagccctttggataacagtgagtcaagaattcagcacatgctgctgaca
gaggacccacagatgcagcccgtgcagacaccctttggggtagttaccttcctccagatc
gttggtgtctgcactgaagagctacactcagcccagcagtggaacgggcagggcatcctg
gagctgctgcggacagtgcctattgctggcggcccctggctgataactgacatgcggagg
ggagagaccatatttgagatcgatccacacctgcaagagagagttgacaaaggcatcgag
acagatggctccaacctgagtggtgtcagtgccaagtgtgcctgggatgacctgagccgg
ccccccgaggatgacgaggacagccggagcatctgcatcggcacacagccccggcgactc
tctggcaaagacacagagcagatccgggagaccctgaggagaggactcgagatcaacagc
aaacctgtccttccaccaatcaaccctcagcggcagaatggcctcgcccacgaccgggcc
ccgagccgcaaagacagcctggaaagtgacagctccacggccatcattccccatgagctg
attcgcacgcggcagcttgagagcgtacatctgaaattcaaccaggagtccggagccctc
attcctctctgcctaaggggcaggctcctgcatggacggcactttacatataaaagtatc
acaggtgacatggccatcacgtttgtctccacgggagtggaaggcgcctttgccactgag
gagcatccttacgcggctcatggaccctggttacaaattctgttgaccgaagagtttgta
gagaaaatgttggaggatttagaagatttgacttctccagaggaattcaaacttcccaaa
gagtacagctggcctgaaaagaagctgaaggtctccatcctgcctgacgtggtgttcgac
agtccgctacactag
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