Homo sapiens (human): 5409
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Entry
5409 CDS
T01001
Symbol
PNMT, PENT, PNMTase
Name
(RefSeq) phenylethanolamine N-methyltransferase
KO
K00553
phenylethanolamine N-methyltransferase [EC:
2.1.1.28
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00350
Tyrosine metabolism
hsa01100
Metabolic pathways
Module
hsa_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Network
nt06028
Dopamine and serotonin metabolism
nt06544
Neuroactive ligand signaling
Element
N01550
Adrenaline metabolism
N01919
Dopamine/Adrenaline metabolism in presynaptic neuron
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
5409 (PNMT)
Enzymes [BR:
hsa01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.28 phenylethanolamine N-methyltransferase
5409 (PNMT)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
NNMT_PNMT_TEMT
Methyltransf_23
Methyltransf_12
Methyltransf_11
Motif
Other DBs
NCBI-GeneID:
5409
NCBI-ProteinID:
NP_002677
OMIM:
171190
HGNC:
9160
Ensembl:
ENSG00000141744
UniProt:
P11086
Structure
PDB
PDBj
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All DBs
Position
17:39668019..39670475
Genome browser
AA seq
282 aa
AA seq
DB search
MSGADRSPNAGAAPDSAPGQAAVASAYQRFEPRAYLRNNYAPPRGDLCNPNGVGPWKLRC
LAQTFATGEVSGRTLIDIGSGPTVYQLLSACSHFEDITMTDFLEVNRQELGRWLQEEPGA
FNWSMYSQHACLIEGKGECWQDKERQLRARVKRVLPIDVHQPQPLGAGSPAPLPADALVS
AFCLEAVSPDLASFQRALDHITTLLRPGGHLLLIGALEESWYLAGEARLTVVPVSEEEVR
EALVRSGYKVRDLRTYIMPAHLQTGVDDVKGVFFAWAQKVGL
NT seq
849 nt
NT seq
+upstream
nt +downstream
nt
atgagcggcgcagaccgtagccccaatgcgggcgcagcccctgactcggccccgggccag
gcggcggtggcttcggcctaccagcgcttcgagccgcgcgcctacctccgcaacaactac
gcgccccctcgcggggacctgtgcaacccgaacggcgtcgggccgtggaagctgcgctgc
ttggcgcagaccttcgccaccggtgaagtgtccggacgcaccctcatcgacattggttca
ggccccaccgtgtaccagctgctcagtgcctgcagccactttgaggacatcaccatgaca
gatttcctggaggtcaaccgccaggagctggggcgctggctgcaggaggagccgggggcc
ttcaactggagcatgtacagccaacatgcctgcctcattgagggcaagggggaatgctgg
caggataaggagcgccagctgcgagccagggtgaaacgggtcctgcccatcgacgtgcac
cagccccagcccctgggtgctgggagcccagctcccctgcctgctgacgccctggtctct
gccttctgcttggaggctgtgagcccagatcttgccagctttcagcgggccctggaccac
atcaccacgctgctgaggcctggggggcacctcctcctcatcggggccctggaggagtcg
tggtacctggctggggaggccaggctgacggtggtgccagtgtctgaggaggaggtgagg
gaggccctggtgcgtagtggctacaaggtccgggacctccgcacctatatcatgcctgcc
caccttcagacaggcgtagatgatgtcaagggcgtcttcttcgcctgggctcagaaggtt
gggctgtga
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