KEGG   Homo sapiens (human): 54539
Entry
54539             CDS       T01001                                 
Symbol
NDUFB11, CI-ESSS, ESSS, MC1DN30, NP17.3, Np15, P17.3
Name
(RefSeq) NADH:ubiquinone oxidoreductase subunit B11
  KO
K11351  NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
Organism
hsa  Homo sapiens (human)
Pathway
hsa00190  Oxidative phosphorylation
hsa01100  Metabolic pathways
hsa04714  Thermogenesis
hsa04723  Retrograde endocannabinoid signaling
hsa04932  Non-alcoholic fatty liver disease
hsa05010  Alzheimer disease
hsa05012  Parkinson disease
hsa05014  Amyotrophic lateral sclerosis
hsa05016  Huntington disease
hsa05020  Prion disease
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05208  Chemical carcinogenesis - reactive oxygen species
hsa05415  Diabetic cardiomyopathy
Module
hsa_M00147  NADH dehydrogenase (ubiquinone) 1 beta subcomplex
Network
nt06460  Alzheimer disease
nt06463  Parkinson disease
nt06464  Amyotrophic lateral sclerosis
nt06466  Pathways of neurodegeneration
nt06529  Thermogenesis
  Element
N00995  Electron transfer in Complex I
N00997  Mutation-caused aberrant Abeta to electron transfer in Complex I
N01042  Mutation-caused aberrant SNCA to electron transfer in Complex I
N01043  Mutation-inactivated PINK1 to electron transfer in Complex I
N01044  MPP+ to electron transfer in Complex I
N01045  Rotenone to electron transfer in Complex I
N01136  Mutation-caused aberrant TDP43 to electron transfer in Complex I
N01691  mitochondrial complex - UCP1 in Thermogenesis
Disease
H00473  Mitochondrial complex I deficiency
H01904  Microphthalmia with linear skin defects syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    54539 (NDUFB11)
 09150 Organismal Systems
  09156 Nervous system
   04723 Retrograde endocannabinoid signaling
    54539 (NDUFB11)
  09159 Environmental adaptation
   04714 Thermogenesis
    54539 (NDUFB11)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    54539 (NDUFB11)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    54539 (NDUFB11)
   05012 Parkinson disease
    54539 (NDUFB11)
   05014 Amyotrophic lateral sclerosis
    54539 (NDUFB11)
   05016 Huntington disease
    54539 (NDUFB11)
   05020 Prion disease
    54539 (NDUFB11)
   05022 Pathways of neurodegeneration - multiple diseases
    54539 (NDUFB11)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    54539 (NDUFB11)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    54539 (NDUFB11)
SSDB
Motif
Pfam: ESSS
Other DBs
NCBI-GeneID: 54539
NCBI-ProteinID: NP_001129470
OMIM: 300403
HGNC: 20372
Ensembl: ENSG00000147123
UniProt: Q9NX14
Structure
LinkDB
Position
X:complement(47142216..47145491)
AA seq 153 aa
MAAGLFGLSARRLLAAAATRGLPAARVRWESSFSRTVVAPSAVAGKRPPEPTTPWQEDPE
PEDENLYEKNPDSHGYDKDPVLDVWNMRLVFFFGVSIILVLGSTFVAYLPDYRMKEWSRR
EAERLVKYREANGLPIMESNCFDPSKIQLPEDE
NT seq 462 nt   +upstreamnt  +downstreamnt
atggcggctgggctgtttggtttgagcgctcgccgtcttttggcggcagcggcgacgcga
gggctcccggccgcccgcgtccgctgggaatctagcttctccaggactgtggtcgccccg
tccgctgtggcgggaaagcggcccccagaaccgaccacaccgtggcaagaggacccagaa
cccgaggacgaaaacttgtatgagaagaacccagactcccatggttatgacaaggacccc
gttttggacgtctggaacatgcgacttgtcttcttctttggcgtctccatcatcctggtc
cttggcagcacctttgtggcctatctgcctgactacaggatgaaagagtggtcccgccgc
gaagctgagaggcttgtgaaataccgagaggccaatggccttcccatcatggaatccaac
tgcttcgaccccagcaagatccagctgccagaggatgagtga

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