KEGG   Homo sapiens (human): 5523
Entry
5523              CDS       T01001                                 
Symbol
PPP2R3A, PPP2R3, PR130, PR72
Name
(RefSeq) protein phosphatase 2 regulatory subunit B''alpha
  KO
K11583  serine/threonine-protein phosphatase 2A regulatory subunit B''
Organism
hsa  Homo sapiens (human)
Pathway
hsa03015  mRNA surveillance pathway
hsa04071  Sphingolipid signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04152  AMPK signaling pathway
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04660  T cell receptor signaling pathway
hsa04728  Dopaminergic synapse
hsa05165  Human papillomavirus infection
Network
nt06166  Human papillomavirus (HPV)
nt06530  PI3K signaling
nt06537  TCR/BCR signaling
  Element
N00355  PP2A-AKT signaling pathway
N00356  HPV E7 to PP2A-AKT signaling patyway
N01579  CD80/CD86-CTLA4-PP2A signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    5523 (PPP2R3A)
 09130 Environmental Information Processing
  09132 Signal transduction
   04071 Sphingolipid signaling pathway
    5523 (PPP2R3A)
   04151 PI3K-Akt signaling pathway
    5523 (PPP2R3A)
   04152 AMPK signaling pathway
    5523 (PPP2R3A)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    5523 (PPP2R3A)
  09156 Nervous system
   04728 Dopaminergic synapse
    5523 (PPP2R3A)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    5523 (PPP2R3A)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    5523 (PPP2R3A)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    5523 (PPP2R3A)
   03036 Chromosome and associated proteins [BR:hsa03036]
    5523 (PPP2R3A)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-2 (PP2A)
    Regulatory subunits
     5523 (PPP2R3A)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   Surveillance factors
    Protein phosphatase 2A
     5523 (PPP2R3A)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   Other centromeric chromatin formation proteins
    PP2A (protein phosphatase 2A)
     5523 (PPP2R3A)
SSDB
Motif
Pfam: EF-hand_13 P2R3B_EF-hand EF-hand_7 EF-hand_1 EF-hand_6 EF-hand_5 DUF4116 DUF3924 DUF4187
Other DBs
NCBI-GeneID: 5523
NCBI-ProteinID: NP_002709
OMIM: 604944
HGNC: 9307
Ensembl: ENSG00000073711
UniProt: Q06190
Structure
LinkDB
Position
3:135965728..136147894
AA seq 1150 aa
MAATYRLVVSTVNHYSSVVIDRRFEQAIHYCTGTCHTFTHGIDCIVVHHSVCADLLHIPV
SQFKDADLNSMFLPHENGLSSAEGDYPQQAFTGIPRVKRGSTFQNTYNLKDIAGEAISFA
SGKIKEFSFEKLKNSNHAAYRKGRKVKSDSFNRRSVDLDLLCGHYNNDGNAPSFGLLRSS
SVEEKPLSHRNSLDTNLTSMFLQNFSEEDLVTQILEKHKIDNFSSGTDIKMCLDILLKCS
EDLKKCTDIIKQCIKKKSGSSISEGSGNDTISSSETVYMNVMTRLASYLKKLPFEFMQSG
NNEALDLTELISNMPSLQLTPFSPVFGTEQPPKYEDVVQLSASDSGRFQTIELQNDKPNS
RKMDTVQSIPNNSTNSLYNLEVNDPRTLKAVQVQSQSLTMNPLENVSSDDLMETLYIEEE
SDGKKALDKGQKTENGPSHELLKVNEHRAEFPEHATHLKKCPTPMQNEIGKIFEKSFVNL
PKEDCKSKVSKFEEGDQRDFTNSSSQEEIDKLLMDLESFSQKMETSLREPLAKGKNSNFL
NSHSQLTGQTLVDLEPKSKVSSPIEKVSPSCLTRIIETNGHKIEEEDRALLLRILESIED
FAQELVECKSSRGSLSQEKEMMQILQETLTTSSQANLSVCRSPVGDKAKDTTSAVLIQQT
PEVIKIQNKPEKKPGTPLPPPATSPSSPRPLSPVPHVNNVVNAPLSINIPRFYFPEGLPD
TCSNHEQTLSRIETAFMDIEEQKADIYEMGKIAKVCGCPLYWKAPMFRAAGGEKTGFVTA
QSFIAMWRKLLNNHHDDASKFICLLAKPNCSSLEQEDFIPLLQDVVDTHPGLTFLKDAPE
FHSRYITTVIQRIFYTVNRSWSGKITSTEIRKSNFLQTLALLEEEEDINQITDYFSYEHF
YVIYCKFWELDTDHDLYISQADLSRYNDQASSSRIIERIFSGAVTRGKTIQKEGRMSYAD
FVWFLISEEDKRNPTSIEYWFRCMDVDGDGVLSMYELEYFYEEQCERMEAMGIEPLPFHD
LLCQMLDLVKPAVDGKITLRDLKRCRMAHIFYDTFFNLEKYLDHEQRDPFAVQKDVENDG
PEPSDWDRFAAEEYETLVAEESAQAQFQEGFEDYETDEPASPSEFGNKSNKILSASLPEK
CGKLQSVDEE
NT seq 3453 nt   +upstreamnt  +downstreamnt
atggcagcaacttacagacttgtggttagtactgtgaaccactacagcagcgtggtgata
gaccggcgttttgaacaagctatacattattgcactggaacctgccacaccttcacacat
ggaattgactgcattgtggtacaccatagtgtttgtgcagacctcttgcacatccctgtg
tctcagttcaaagatgcagatctgaactctatgtttctaccccatgaaaatgggctttct
tcggctgaaggagactatccccaacaggccttcacaggcatacccagggtcaagagagga
tctacatttcagaatacctacaacttaaaggatattgcaggagaagcaatcagttttgcc
agtgggaaaataaaagaattttcctttgaaaaactcaaaaactctaaccatgcagcttac
agaaagggaaggaaagttaagtctgactcatttaataggaggtcagttgatttggacttg
ctttgtggccattataacaacgatgggaacgccccatcctttggtttactgcggagttcc
tcagttgaggaaaaacctttgtctcatagaaactcactggatacgaacctgacttccatg
tttcttcaaaacttttctgaagaagacttggttactcagattttggaaaaacataaaata
gataatttttcttctgggacagacataaagatgtgcttggacatcttattgaaatgctcc
gaggatttaaaaaaatgcacagacatcataaaacaatgcataaagaaaaaatcagggagt
agcatcagtgaaggaagtggtaatgatacaatttctagctctgaaactgtctatatgaat
gtaatgaccaggttagcatcctatctgaaaaagttaccatttgaattcatgcagtctggg
aataatgaggctctagatttaacagaactgatcagtaatatgcctagcttacaactgact
cccttctccccagtgtttggcactgaacaaccccctaaatatgaagatgttgtccagctc
tcagcttctgactctggacgatttcaaactattgaattgcaaaatgacaagcctaattct
aggaagatggacactgtacaatccattccaaacaactccacaaattccttatataactta
gaggtaaatgatcctagaactctaaaagctgtccaggtccaatcacagtcattaaccatg
aatcctttagaaaatgtttcttctgacgacttaatggaaactctttatattgaagaagag
tcagatggaaagaaagcattagataaaggacaaaagacagagaatggacctagtcatgag
ttattaaaggtaaatgaacatagagcagaatttccagaacatgctactcatcttaaaaaa
tgccccaccccaatgcaaaatgaaattggtaagatatttgagaaatcatttgttaatcta
cctaaggaagactgtaaatcaaaagtttctaaatttgaagagggagaccagagagatttt
acaaattccagtagccaggaagagatagataaattgttaatggatttggaatctttttca
cagaagatggagacctctctaagagagccacttgcgaagggtaaaaactctaatttttta
aatagtcacagtcagttgaccggtcagacccttgtagatcttgagcctaaatctaaagtc
tcttcacccatagaaaaagtctcaccttcctgtctaacaaggattattgaaaccaatgga
cacaaaatagaggaagaggatcgagccctcttactgcgaatcctggaaagcattgaagac
tttgctcaagaactagttgaatgcaaatcaagcagagggagcctatcacaagaaaaggaa
atgatgcaaattctacaggaaaccttgacaacttcctcccaggccaatttatcagtctgt
agaagtcctgttggtgataaagccaaagatactacttcagcagttttgattcagcagact
ccagaggtgatcaagattcaaaataaaccagaaaagaaacctggaacaccactcccacct
ccagccacctctccaagtagtccccgacctctctccccggttccccatgtgaataatgtt
gtgaatgcgccattgtccataaacattccacggttctactttcctgaaggactcccagat
acctgtagtaatcatgaacaaactctaagcagaattgaaactgctttcatggatattgaa
gaacagaaagcagacatttatgaaatggggaaaattgcaaaggtctgtggctgtcctctc
tattggaaagcccccatgttcagggctgcagggggagagaagacaggatttgtgacagca
cagtcattcattgccatgtggagaaagttgctgaataaccatcatgatgatgcctctaaa
ttcatctgtcttctagcaaagcccaactgcagctctctagaacaggaggatttcatccct
ctacttcaggatgtggtggatacccaccctggtctcacgttcctgaaagatgctccagaa
ttccactcccgctacatcaccacggttattcagagaatattctacacagtcaacagatct
tggagtggaaaaattacttcgacagagataagaaaaagcaactttttgcaaaccctagca
cttttggaagaagaggaagatataaaccaaattacagattacttctcctatgaacatttc
tatgttatttattgtaaattctgggaactagatactgatcacgacctctacatcagccag
gccgatctgtctcgatacaatgaccaggcttcatcaagcaggattattgaaaggatattc
tctggtgcagtaacaaggggaaaaacaatacagaaagagggaagaatgagctatgcagat
tttgtttggtttttgatctctgaagaagacaaaaggaatcctaccagcattgagtattgg
ttccgctgcatggatgtggatggagacggtgtactctccatgtatgagctggagtacttc
tatgaggagcagtgtgaacggatggaagccatgggaattgagcccttgccattccatgat
ttactgtgccagatgcttgacctagtgaagccagctgttgatggcaaaataactctaaga
gatctgaagaggtgcagaatggctcacatcttctatgacactttctttaatctggagaaa
tacttagaccatgaacagagagatccctttgcggtccagaaggatgttgagaacgatggg
cctgagccctcagactgggaccggtttgccgctgaggagtatgagacgcttgttgcagag
gaatctgcccaagcacaattccaggaaggctttgaagattatgaaacagatgaacctgcc
tctccctctgaatttggaaacaaaagcaataaaatattaagtgcaagccttccagagaaa
tgtggaaagcttcaatcagtggatgaagaatag

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