| Entry |
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| Name |
HPV E7 to PP2A-AKT signaling patyway
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| Definition |
E7 -| PP2A |
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| Expanded |
K21809 -| ((5515,5516)+(5518,5519)+(5520,5521,5522,55844,5523,28227,55012,5525,5526,5527,5528,5529)) |
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| Class |
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| Type |
Pathogen
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| Pathway |
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| Disease |
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| Gene |
| 5515 | PPP2CA; protein phosphatase 2 catalytic subunit alpha |
| 5516 | PPP2CB; protein phosphatase 2 catalytic subunit beta |
| 5518 | PPP2R1A; protein phosphatase 2 scaffold subunit Aalpha |
| 5519 | PPP2R1B; protein phosphatase 2 scaffold subunit Abeta |
| 5520 | PPP2R2A; protein phosphatase 2 regulatory subunit Balpha |
| 5521 | PPP2R2B; protein phosphatase 2 regulatory subunit Bbeta |
| 5522 | PPP2R2C; protein phosphatase 2 regulatory subunit Bgamma |
| 55844 | PPP2R2D; protein phosphatase 2 regulatory subunit Bdelta |
| 5523 | PPP2R3A; protein phosphatase 2 regulatory subunit B''alpha |
| 28227 | PPP2R3B; protein phosphatase 2 regulatory subunit B''beta |
| 55012 | PPP2R3C; protein phosphatase 2 regulatory subunit B''gamma |
| 5525 | PPP2R5A; protein phosphatase 2 regulatory subunit B'alpha |
| 5526 | PPP2R5B; protein phosphatase 2 regulatory subunit B'beta |
| 5527 | PPP2R5C; protein phosphatase 2 regulatory subunit B'gamma |
| 5528 | PPP2R5D; protein phosphatase 2 regulatory subunit B'delta |
| 5529 | PPP2R5E; protein phosphatase 2 regulatory subunit B'epsilon |
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| Perturbant |
| K21809 (E7) | E7; HPV protein E7 |
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| Reference |
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| Authors |
Zhang L, Wu J, Ling MT, Zhao L, Zhao KN |
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| Title |
The role of the PI3K/Akt/mTOR signalling pathway in human cancers induced by infection with human papillomaviruses. |
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| Journal |
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| Reference |
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| Authors |
Pim D, Massimi P, Dilworth SM, Banks L |
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| Title |
Activation of the protein kinase B pathway by the HPV-16 E7 oncoprotein occurs through a mechanism involving interaction with PP2A. |
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| Journal |
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| LinkDB |
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