Homo sapiens (human): 55755
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Entry
55755 CDS
T01001
Symbol
CDK5RAP2, C48, Cep215, MCPH3
Name
(RefSeq) CDK5 regulatory subunit associated protein 2
KO
K16542
CDK5 regulatory subunit-associated protein 2
Organism
hsa
Homo sapiens (human)
Network
nt06515
Regulation of kinetochore-microtubule interactions
Element
N01544
Microtubule nucleation
Disease
H00269
Primary microcephaly
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
hsa03036
]
55755 (CDK5RAP2)
Chromosome and associated proteins [BR:
hsa03036
]
Eukaryotic type
Centrosome formation proteins
Pericentriolar materials (PCM)
Other PCM proteins
55755 (CDK5RAP2)
Centrosome duplication proteins
Regulators of centriole replication
55755 (CDK5RAP2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Cnn_1N
Motif
Other DBs
NCBI-GeneID:
55755
NCBI-ProteinID:
NP_060719
OMIM:
608201
HGNC:
18672
Ensembl:
ENSG00000136861
UniProt:
Q96SN8
B3KVI2
Structure
PDB
LinkDB
All DBs
Position
9:complement(120388875..120580167)
Genome browser
AA seq
1893 aa
AA seq
DB search
MMDLVLEEDVTVPGTLSGCSGLVPSVPDDLDGINPNAGLGNGLLPNVSEETVSPTRARNM
KDFENQITELKKENFNLKLRIYFLEERMQQEFHGPTEHIYKTNIELKVEVESLKRELQER
EQLLIKASKAVESLAEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEKDVTAAQAELEK
AFAGTETEKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSLKSKEALIQCL
KEEKSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKERNSFEERIQALEEDLR
EKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEIEKLSAAFAKAREALQKAQT
QEFQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSIKKITQELSDLQQERERLEK
DLEEAHREKSKGDCTIRDLRNEVEKLRNEVNEREKAMENRYKSLLSESNKKLHNQEQVIK
HLTESTNQKDVLLQKFNEKDLEVIQQNCYLMAAEDLELRSEGLITEKCSSQQPPGSKTIF
SKEKKQSSDYEELIQVLKKEQDIYTHLVKSLQESDSINNLQAELNKIFALRKQLEQDVLS
YQNLRKTLEEQISEIRRREEESFSLYSDQTSYLSICLEENNRFQVEHFSQEELKKKVSDL
IQLVKELYTDNQHLKKTIFDLSCMGFQGNGFPDRLASTEQTELLASKEDEDTIKIGEDDE
INFLSDQHLQQSNEIMKDLSKGGCKNGYLRHTESKISDCDGAHAPGCLEEGAFINLLAPL
FNEKATLLLESRPDLLKVVRELLLGQLFLTEQEVSGEHLDGKTEKTPKQKGELVHFVQTN
SFSKPHDELKLSCEAQLVKAGEVPKVGLKDASVQTVATEGDLLRFKHEATREAWEEKPIN
TALSAEHRPENLHGVPGWQAALLSLPGITNREAKKSRLPILIKPSRSLGNMYRLPATQEV
VTQLQSQILELQGELKEFKTCNKQLHQKLILAEAVMEGRPTPDKTLLNAQPPVGAAYQDS
PGEQKGIKTTSSVWRDKEMDSDQQRSYEIDSEICPPDDLASLPSCKENPEDVLSPTSVAT
YLSSKSQPSAKVSVMGTDQSESINTSNETEYLKQKIHDLETELEGYQNFIFQLQKHSQCS
EAIITVLCGTEGAQDGLSKPKNGSDGEEMTFSSLHQVRYVKHVKILGPLAPEMIDSRVLE
NLKQQLEEQEYKLQKEQNLNMQLFSEIHNLQNKFRDLSPPRYDSLVQSQARELSLQRQQI
KDGHGICVISRQHMNTMIKAFEELLQASDVDYCVAEGFQEQLNQCAELLEKLEKLFLNGK
SVGVEMNTQNELMERIEEDNLTYQHLLPESPEPSASHALSDYETSEKSFFSRDQKQDNET
EKTSVMVNSFSQDLLMEHIQEIRTLRKRLEESIKTNEKLRKQLERQGSEFVQGSTSIFAS
GSELHSSLTSEIHFLRKQNQALNAMLIKGSRDKQKENDKLRESLSRKTVSLEHLQREYAS
VKEENERLQKEGSEKERHNQQLIQEVRCSGQELSRVQEEVKLRQQLLSQNDKLLQSLRVE
LKAYEKLDEEHRRLREASGEGWKGQDPFRDLHSLLMEIQALRLQLERSIETSSTLQSRLK
EQLARGAEKAQEGALTLAVQAVSIPEVPLQPDKHDGDKYPMESDNSFDLFDSSQAVTPKS
VSETPPLSGNDTDSLSCDSGSSATSTPCVSRLVTGHHLWASKNGRHVLGLIEDYEALLKQ
ISQGQRLLAEMDIQTQEAPSSTSQELGTKGPHPAPLSKFVSSVSTAKLTLEEAYRRLKLL
WRVSLPEDGQCPLHCEQIGEMKAEVTKLHKKLFEQEKKLQNTMKLLQLSKRQEKVIFDQL
VVTHKILRKARGNLELRPGGAHPGTCSPSRPGS
NT seq
5682 nt
NT seq
+upstream
nt +downstream
nt
atgatggacttggtgttggaagaggacgtcaccgtccctgggacgctcagcggctgcagt
ggccttgttcccagtgtaccagatgacctggatggcatcaaccccaatgctgggttggga
aatggtctgctcccaaatgtgtcagaagaaacagtgtctcccaccagagcacggaacatg
aaggactttgaaaatcaaatcactgaattgaagaaagaaaactttaacctaaagctccgc
atctatttccttgaggaaagaatgcaacaggaatttcatggccccactgaacatatctac
aaaactaacattgagctcaaggtggaagtagaaagtctgaagcgggaactccaggagaga
gagcagctgctcatcaaagcctccaaagcagttgagagcttagctgaagcaggtggctct
gaaatccagcgggtgaaagaagatgctcgaaagaaggtgcagcaggtggaagatctccta
actaaaagaatactccttttggaaaaggatgtgacagccgcccaggcagaactggaaaag
gcctttgcagggacagagacggagaaggctcttcggttgcgtttggaaagcaagctttca
gagatgaagaagatgcacgagggggacttggcgatggctctggtcctggatgagaaagac
agactgattgaggagttgaagctgtctttgaagagcaaagaagctttaattcagtgcctt
aaagaggagaaatctcagatggcatgtcctgatgagaatgtgtcatctggagagctccga
ggactttgtgctgctccaagggaagaaaaggagagagaaactgaggctgcacaaatggag
catcagaaggagagaaacagctttgaagagaggatccaggcacttgaagaggacctgaga
gagaaggaaagagaaattgctacagagaagaaaaatagtctaaagagggataaagccatt
cagggtttaaccatggcattaaaatcaaaggaaaaaaaggttgaagaacttaactctgaa
attgaaaagctcagtgctgcctttgctaaagccagagaggccctacagaaagcacagacc
caggaatttcaggggtctgaagactatgagactgctctatcaggaaaggaagccctttcg
gctgcgctgcgctcacaaaacctcaccaagagtacagagaaccacagactgcgtagaagc
attaagaagatcacccaggagctgagtgacttgcagcaggagagggagagactggagaag
gacctggaggaagcccatcgagagaagagcaaaggagactgcaccatccgtgatcttaga
aatgaagttgaaaaattacgcaatgaagtgaatgaaagagagaaagcaatggaaaatcgt
tacaagagtcttctgagtgaaagcaataaaaaattgcacaatcaagagcaagtgatcaaa
catctaacagaaagtaccaatcagaaggacgtgttgcttcagaaattcaatgaaaaagat
ttggaagtaatacagcagaactgctatttaatggctgcagaggatcttgagctcaggagt
gaaggcttaataacagaaaagtgctcttctcaacagccaccaggcagcaaaaccatcttc
tctaaggaaaagaaacaatcatcagactatgaagagctgattcaggtcttaaagaaagag
caggacatctatacccatctggtcaaatctctgcaggaatcagacagtatcaacaacctg
caggctgagttaaacaagatttttgccctgcggaagcaactggagcaggatgtgctttca
tatcagaatttgcggaagaccttggaggagcagatcagcgaaattcggaggcgggaagaa
gaatcattttcactttatagtgatcaaacatcttatctaagtatttgccttgaagaaaac
aatcggtttcaagtggaacatttttctcaagaagaacttaagaaaaaggtcagtgacctt
atacagctagtgaaggagctgtatacagacaaccagcacctgaagaaaaccatttttgat
ctctcctgcatgggtttccagggaaatgggtttccagatagacttgcgtctacagaacaa
acagagcttctggctagcaaggaggacgaggacacgatcaaaattggggaggatgacgag
attaatttcctgagtgaccagcatttgcagcagagtaatgagattatgaaagacctttcc
aaaggaggctgcaaaaatggatacttaaggcacacggagtctaagatttcagattgtgat
ggggcccacgcacctggctgcctagaagaaggtgcattcataaacctgcttgcccctttg
ttcaatgagaaggccacattattactggaatccaggccagaccttctgaaagtggtacgg
gaactgcttctgggacaactattcttgacagagcaggaagtttctggagaacaccttgat
ggtaaaactgagaagacacctaagcaaaaaggtgaacttgtacattttgtccaaaccaac
tcattttccaagccacatgatgaactgaagttgtcttgtgaggcccagctagtaaaggca
ggcgaagtgcccaaggtaggactgaaagatgcctcagtgcagactgtggccacggagggc
gacctgctgagattcaagcatgaagcaacaagagaggcttgggaagagaaaccgatcaac
actgcactcagcgcagagcatcggccagagaacctgcacggggtgcctgggtggcaggct
gccctcctttccctccctggtattaccaacagagaggctaagaagtcccgcttgccaatc
ctaataaaaccatcccggtcattaggaaatatgtatcgtctccctgccacccaggaggtg
gtgacgcagctgcagagccagatcttggagctgcagggggagctgaaggagtttaaaact
tgtaataagcaacttcaccaaaagttaattctggctgaagcagtgatggaggggaggcca
acgcccgacaaaacgttgctgaatgctcagccccctgtgggagcagcctaccaggacagc
ccaggagagcagaaaggaattaaaaccacatcttctgtctggagagacaaggaaatggac
agtgatcagcaaagaagctacgagattgactctgagatttgcccacctgatgaccttgcc
agcttgccatcatgcaaagaaaatcctgaagatgttctgagcccaacttcagtagctact
tacctgagttccaagagtcagccttctgctaaagtcagtgtgatggggactgatcagtca
gagagcattaatacctcaaatgagacagaatacttaaaacagaaaatccatgacttggaa
actgagctggaaggctaccagaatttcatatttcagcttcaaaagcactcccagtgcagt
gaggccataattacagttttgtgtgggacagaaggggcccaggatggcttgagcaagccc
aagaatggttctgatggggaagaaatgaccttttcaagtttgcaccaagtgcgatacgtg
aaacacgtgaaaatcctcggtccgctggccccagagatgattgacagcagggtgctggag
aacctcaaacagcagctggaggaacaggaatacaagctgcagaaggagcagaatttgaac
atgcaacttttcagtgagatccataatctgcagaataagttcagagatctctcacctccc
agatacgattcattagttcagtcccaagccagggagctctcccttcaacggcagcagatt
aaggatggccatggcatctgtgtcatctcccgtcaacacatgaacaccatgattaaggca
tttgaggagttgctgcaggccagtgatgtggattactgtgtggccgagggtttccaggaa
cagctgaatcaatgtgctgagctgctggagaaattggaaaagctatttctcaacggaaaa
tcagttggagtggaaatgaacacccagaatgaactgatggagaggattgaggaagacaac
ttaacctaccaacatcttctgcctgaatctcctgagccttcagcctctcatgcgctctct
gattatgaaacatctgaaaagtccttcttctcacgagaccagaagcaagataatgagaca
gagaagacttcagttatggtgaacagtttttctcaagacttactaatggaacacatacag
gaaattcgaactttgagaaagcgtttagaagaatctattaaaacaaatgagaagctacgg
aaacagttggaacggcaaggatctgaatttgttcaaggttctacaagcatttttgcttct
ggttcagagcttcatagttctctaacatcagaaattcatttcttgaggaagcagaaccag
gccctcaatgcaatgctcattaaaggatccagagataaacagaaggagaatgacaaatta
cgagagtccctctccaggaagaccgtgagcctggagcaccttcagcgggagtatgccagc
gtgaaggaagaaaatgaaaggctgcagaaagaaggcagcgagaaggagagacacaaccag
cagctgatccaggaggtccgctgcagcggccaggagctgagcagggtgcaggaggaggtg
aagttgaggcagcagctgctctcacagaatgacaagctattgcagtctctccgagtggag
ctgaaggcgtatgagaagctggatgaagagcacaggagactgagagaggcgtcgggagaa
ggctggaaggggcaggatcctttcagggacctgcacagcctcctgatggagatccaggct
ctgcgcttgcaactagaaaggagcatcgaaaccagcagcactctgcagagcaggctcaag
gaacagctggcaaggggggcagagaaggcacaggaaggagccctcactctggctgtccaa
gccgtgtccatccctgaggtgccccttcagcctgacaaacacgatggtgacaaatatccc
atggaaagtgataattcatttgatctgtttgattcctcccaggcagtgacaccaaaatca
gtttcagagactcctccactctctgggaatgacacggactccctctcctgcgacagtggc
agttcggcaactagcactccgtgtgtgtcccgcctggtcactggccaccacctgtgggcc
agcaagaatggccgccatgtcctgggcctgattgaggactatgaggccctgctcaaacag
atcagccagggacagaggctccttgctgaaatggacattcaaacccaagaggctcccagc
tccacaagtcaagagctgggaacaaagggtccacacccagcaccactgagcaagtttgtg
agcagtgtgagcacggccaagctgaccctggaagaggcctacaggcggctgaagcttctc
tggagagtctcactccccgaggatggccagtgcccccttcactgtgagcagattggagaa
atgaaggcagaggtcaccaaactacataaaaaattgtttgaacaagaaaagaagttgcaa
aacaccatgaagcttttgcagctgagcaagcgccaggaaaaagtcatctttgatcaattg
gtcgtaacccacaaaatccttcggaaggccagaggaaacctggagcttaggcctggggga
gcccatccaggaacatgcagtcccagcagaccaggctcctga
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