KEGG   NETWORK: N01544
Entry
N01544                      Network                                
Name
Microtubule nucleation
Definition
CDK5RAP2 == gamma-TuRC+TPX2 == ch-TOG == microtubule
  Expanded
55755 == (10844+10426+27229+114791+85378+653784+80097+121441)+22974 == 9793 == (7846,10376,84790,7278,113457,112714,7277,51807)+(203068,81027,7280,347733,10381,10382,10383,84617,347688)
Class
nt06515 Regulation of kinetochore-microtubule interactions
Type
Reference
Gene
55755  CDK5RAP2; CDK5 regulatory subunit associated protein 2
10844  TUBGCP2; tubulin gamma complex associated protein 2
10426  TUBGCP3; tubulin gamma complex associated protein 3
27229  TUBGCP4; tubulin gamma complex associated protein 4
114791  TUBGCP5; tubulin gamma complex associated protein 5
85378  TUBGCP6; tubulin gamma complex associated protein 6
653784  MZT2A; mitotic spindle organizing protein 2A
80097  MZT2B; mitotic spindle organizing protein 2B
121441  NEDD1; NEDD1 gamma-tubulin ring complex targeting factor
22974  TPX2; TPX2 microtubule nucleation factor
9793  CKAP5; cytoskeleton associated protein 5
7846  TUBA1A; tubulin alpha 1a
10376  TUBA1B; tubulin alpha 1b
84790  TUBA1C; tubulin alpha 1c
7278  TUBA3C; tubulin alpha 3c
113457  TUBA3D; tubulin alpha 3d
112714  TUBA3E; tubulin alpha 3e
7277  TUBA4A; tubulin alpha 4a
51807  TUBA8; tubulin alpha 8
203068  TUBB; tubulin beta class I
81027  TUBB1; tubulin beta 1 class VI
7280  TUBB2A; tubulin beta 2A class IIa
347733  TUBB2B; tubulin beta 2B class IIb
10381  TUBB3; tubulin beta 3 class III
10382  TUBB4A; tubulin beta 4A class IVa
10383  TUBB4B; tubulin beta 4B class IVb
84617  TUBB6; tubulin beta 6 class V
347688  TUBB8; tubulin beta 8 class VIII
Reference
PMID:33190097
  Authors
Liu P, Wurtz M, Zupa E, Pfeffer S, Schiebel E
  Title
Microtubule nucleation: The waltz between gamma-tubulin ring complex and associated proteins.
  Journal
Curr Opin Cell Biol 68:124-131 (2021)
DOI:10.1016/j.ceb.2020.10.004
Reference
PMID:36164503
  Authors
Nakamura A, Ikeda M, Kusayanagi S, Hayashi K
  Title
An alternative splice isoform of mouse CDK5RAP2 induced cytoplasmic microtubule nucleation.
  Journal
IBRO Neurosci Rep 13:264-273 (2022)
DOI:10.1016/j.ibneur.2022.09.004
Reference
PMID:34297125
  Authors
Thawani A, Petry S
  Title
Molecular insight into how gamma-TuRC makes microtubules.
  Journal
J Cell Sci 134:jcs245464 (2021)
DOI:10.1242/jcs.245464
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