Homo sapiens (human): 5624
Help
Entry
5624 CDS
T01001
Symbol
PROC, APC, PC, PROC1, THPH3, THPH4
Name
(RefSeq) protein C, inactivator of coagulation factors Va and VIIIa
KO
K01344
protein C (activated) [EC:
3.4.21.69
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04610
Complement and coagulation cascades
Network
nt06514
Coagulation cascade
Element
N01515
Regulation of coagulation cascade, protein C system
Disease
H00223
Inherited thrombophilia
H01723
Deep vein thrombosis
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09151 Immune system
04610 Complement and coagulation cascades
5624 (PROC)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
hsa01002
]
5624 (PROC)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.21 Serine endopeptidases
3.4.21.69 activated protein C (thrombin-activated peptidase)
5624 (PROC)
Peptidases and inhibitors [BR:
hsa01002
]
Serine peptidases
Family S1: chymotrypsin family
5624 (PROC)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Trypsin
Gla
FXa_inhibition
hEGF
EGF
DUF1986
EGF_Teneurin
EGF_TEN
cEGF
EGF_CA
Trypsin_2
EGF_DL_JAG
EGF_2
JAG1-like_EGF2
Plasmod_Pvs28
Motif
Other DBs
NCBI-GeneID:
5624
NCBI-ProteinID:
NP_000303
OMIM:
612283
HGNC:
9451
Ensembl:
ENSG00000115718
CPD:
C22547
UniProt:
P04070
Structure
PDB
PDBj
LinkDB
All DBs
Position
2:127418427..127429242
Genome browser
AA seq
461 aa
AA seq
DB search
MWQLTSLLLFVATWGISGTPAPLDSVFSSSERAHQVLRIRKRANSFLEELRHSSLERECI
EEICDFEEAKEIFQNVDDTLAFWSKHVDGDQCLVLPLEHPCASLCCGHGTCIDGIGSFSC
DCRSGWEGRFCQREVSFLNCSLDNGGCTHYCLEEVGWRRCSCAPGYKLGDDLLQCHPAVK
FPCGRPWKRMEKKRSHLKRDTEDQEDQVDPRLIDGKMTRRGDSPWQVVLLDSKKKLACGA
VLIHPSWVLTAAHCMDESKKLLVRLGEYDLRRWEKWELDLDIKEVFVHPNYSKSTTDNDI
ALLHLAQPATLSQTIVPICLPDSGLAERELNQAGQETLVTGWGYHSSREKEAKRNRTFVL
NFIKIPVVPHNECSEVMSNMVSENMLCAGILGDRQDACEGDSGGPMVASFHGTWFLVGLV
SWGEGCGLLHNYGVYTKVSRYLDWIHGHIRDKEAPQKSWAP
NT seq
1386 nt
NT seq
+upstream
nt +downstream
nt
atgtggcagctcacaagcctcctgctgttcgtggccacctggggaatttccggcacacca
gctcctcttgactcagtgttctccagcagcgagcgtgcccaccaggtgctgcggatccgc
aaacgtgccaactccttcctggaggagctccgtcacagcagcctggagcgggagtgcata
gaggagatctgtgacttcgaggaggccaaggaaattttccaaaatgtggatgacacactg
gccttctggtccaagcacgtcgacggtgaccagtgcttggtcttgcccttggagcacccg
tgcgccagcctgtgctgcgggcacggcacgtgcatcgacggcatcggcagcttcagctgc
gactgccgcagcggctgggagggccgcttctgccagcgcgaggtgagcttcctcaattgc
tcgctggacaacggcggctgcacgcattactgcctagaggaggtgggctggcggcgctgt
agctgtgcgcctggctacaagctgggggacgacctcctgcagtgtcaccccgcagtgaag
ttcccttgtgggaggccctggaagcggatggagaagaagcgcagtcacctgaaacgagac
acagaagaccaagaagaccaagtagatccgcggctcattgatgggaagatgaccaggcgg
ggagacagcccctggcaggtggtcctgctggactcaaagaagaagctggcctgcggggca
gtgctcatccacccctcctgggtgctgacagcggcccactgcatggatgagtccaagaag
ctccttgtcaggcttggagagtatgacctgcggcgctgggagaagtgggagctggacctg
gacatcaaggaggtcttcgtccaccccaactacagcaagagcaccaccgacaatgacatc
gcactgctgcacctggcccagcccgccaccctctcgcagaccatagtgcccatctgcctc
ccggacagcggccttgcagagcgcgagctcaatcaggccggccaggagaccctcgtgacg
ggctggggctaccacagcagccgagagaaggaggccaagagaaaccgcaccttcgtcctc
aacttcatcaagattcccgtggtcccgcacaatgagtgcagcgaggtcatgagcaacatg
gtgtctgagaacatgctgtgtgcgggcatcctcggggaccggcaggatgcctgcgagggc
gacagtggggggcccatggtcgcctccttccacggcacctggttcctggtgggcctggtg
agctggggtgagggctgtgggctccttcacaactacggcgtttacaccaaagtcagccgc
tacctcgactggatccatgggcacatcagagacaaggaagccccccagaagagctgggca
ccttag
DBGET
integrated database retrieval system
