Homo sapiens (human): 5704
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Entry
5704 CDS
T01001
Symbol
PSMC4, MIP224, RPT3, S6, TBP-7, TBP7
Name
(RefSeq) proteasome 26S subunit, ATPase 4
KO
K03063
26S proteasome regulatory subunit T3
Organism
hsa
Homo sapiens (human)
Pathway
hsa03050
Proteasome
hsa05010
Alzheimer disease
hsa05012
Parkinson disease
hsa05014
Amyotrophic lateral sclerosis
hsa05016
Huntington disease
hsa05017
Spinocerebellar ataxia
hsa05020
Prion disease
hsa05022
Pathways of neurodegeneration - multiple diseases
hsa05169
Epstein-Barr virus infection
Network
nt06460
Alzheimer disease
nt06461
Huntington disease
nt06463
Parkinson disease
nt06464
Amyotrophic lateral sclerosis
nt06465
Prion disease
nt06466
Pathways of neurodegeneration
Element
N01029
26S proteasome-mediated protein degradation
N01030
Mutation-caused aberrant SNCA to 26S proteasome-mediated protein degradation
N01060
Mutation-caused aberrant Abeta to 26S proteasome-mediated protein degradation
N01061
Mutation-caused aberrant Htt to 26S proteasome-mediated protein degradation
N01144
Mutation-caused aberrant SOD1 to 26S proteasome-mediated protein degradation
N01145
Mutation-inactivated VCP to 26S proteasome-mediated protein degradation
N01146
Mutation-inactivated UBQLN2 to 26S proteasome-mediated protein degradation
N01197
Scrapie conformation PrPSc to 26S proteasome-mediated protein degradation
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03050 Proteasome
5704 (PSMC4)
09160 Human Diseases
09172 Infectious disease: viral
05169 Epstein-Barr virus infection
5704 (PSMC4)
09164 Neurodegenerative disease
05010 Alzheimer disease
5704 (PSMC4)
05012 Parkinson disease
5704 (PSMC4)
05014 Amyotrophic lateral sclerosis
5704 (PSMC4)
05016 Huntington disease
5704 (PSMC4)
05017 Spinocerebellar ataxia
5704 (PSMC4)
05020 Prion disease
5704 (PSMC4)
05022 Pathways of neurodegeneration - multiple diseases
5704 (PSMC4)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03051 Proteasome [BR:
hsa03051
]
5704 (PSMC4)
Proteasome [BR:
hsa03051
]
Eukaryotic proteasome
Regulatory particles
PA700 (19S proteasome)
ATPase subunits
5704 (PSMC4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AAA
Prot_ATP_ID_OB_C
AAA_5
AAA_2
AAA_lid_3
AAA_16
RuvB_N
AAA_22
nSTAND3
DUF815
NPHP3_N
AAA_28
RNA_helicase
Mg_chelatase
AAA_14
TIP49
NTPase_1
ATPase_2
NACHT
AAA_3
IstB_IS21
AAA_7
TsaE
AAA_18
AAA_33
Parvo_NS1
AAA_lid_PRS2_C
AAA_17
AAA_25
NB-ARC
AAA_24
ABC_tran
DUF3450
Motif
Other DBs
NCBI-GeneID:
5704
NCBI-ProteinID:
NP_006494
OMIM:
602707
HGNC:
9551
Ensembl:
ENSG00000013275
UniProt:
P43686
A8K2M0
Structure
PDB
PDBj
LinkDB
All DBs
Position
19:39971165..39981764
Genome browser
AA seq
418 aa
AA seq
DB search
MEEIGILVEKAQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYKKLQQELEFLEVQEEY
IKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTID
RELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREA
VELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYL
GEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFD
QNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDL
EDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK
NT seq
1257 nt
NT seq
+upstream
nt +downstream
nt
atggaggagataggcatcttggtggagaaggctcaggatgagatcccagcactgtccgtg
tcccggccccagaccggcctgtccttcctgggccctgagcctgaggacctggaggacctg
tacagccgctacaagaagctgcagcaagagctggagttcctggaggtgcaggaggaatac
atcaaagatgagcaaaagaacctgaaaaaggaatttctccatgcccaggaggaggtgaag
cgaatccaaagcatcccgctggtcatcggacaatttctggaggctgtggatcagaataca
gccatcgtgggctctaccacaggctccaactattatgtgcgcatcctgagcaccatcgat
cgggagctgctcaagcccaacgcctcagtggccctccacaagcacagcaatgcactggtg
gacgtgctgccccccgaagccgacagcagcatcatgatgctcacctcagaccagaagcca
gatgtgatgtacgcggacatcggaggcatggacatccagaagcaggaggtgcgggaggcc
gtggagctcccgctcacgcatttcgagctctacaagcagatcggcatcgatcccccccga
ggcgtcctcatgtatggcccacctggctgtgggaagaccatgttggcaaaggcggtggca
catcacacaacagctgcattcatccgggtcgtgggctcggagtttgtacagaagtatctg
ggtgagggcccccgcatggtccgggatgtgttccgcctggccaaggagaatgcacctgcc
atcatcttcatagacgagattgatgccatcgccaccaagagattcgatgctcagacaggg
gccgacagggaggttcagaggatcctgctggagctgctgaatcagatggatggatttgat
cagaatgtcaatgtcaaggtaatcatggccacaaacagagcagacaccctggatccggcc
ctgctacggccaggacggctggaccgtaaaattgaatttccacttcctgaccgccgccag
aagagattgattttctccactatcactagcaagatgaacctctctgaggaggttgacttg
gaagactatgtggcccggccagataagatttcaggagctgatattaactccatctgtcag
gagagtggaatgttggctgtccgtgaaaaccgctacattgtcctggccaaggacttcgag
aaagcatacaagactgtcatcaagaaggacgagcaggagcatgagttttacaagtga
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integrated database retrieval system
