Homo sapiens (human): 5707
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Entry
5707 CDS
T01001
Symbol
PSMD1, P112, Rpn2, S1
Name
(RefSeq) proteasome 26S subunit, non-ATPase 1
KO
K03032
26S proteasome regulatory subunit N2
Organism
hsa
Homo sapiens (human)
Pathway
hsa03050
Proteasome
hsa05010
Alzheimer disease
hsa05012
Parkinson disease
hsa05014
Amyotrophic lateral sclerosis
hsa05016
Huntington disease
hsa05017
Spinocerebellar ataxia
hsa05020
Prion disease
hsa05022
Pathways of neurodegeneration - multiple diseases
hsa05169
Epstein-Barr virus infection
Network
nt06460
Alzheimer disease
nt06461
Huntington disease
nt06463
Parkinson disease
nt06464
Amyotrophic lateral sclerosis
nt06465
Prion disease
nt06466
Pathways of neurodegeneration
Element
N01029
26S proteasome-mediated protein degradation
N01030
Mutation-caused aberrant SNCA to 26S proteasome-mediated protein degradation
N01060
Mutation-caused aberrant Abeta to 26S proteasome-mediated protein degradation
N01061
Mutation-caused aberrant Htt to 26S proteasome-mediated protein degradation
N01144
Mutation-caused aberrant SOD1 to 26S proteasome-mediated protein degradation
N01145
Mutation-inactivated VCP to 26S proteasome-mediated protein degradation
N01146
Mutation-inactivated UBQLN2 to 26S proteasome-mediated protein degradation
N01197
Scrapie conformation PrPSc to 26S proteasome-mediated protein degradation
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03050 Proteasome
5707 (PSMD1)
09160 Human Diseases
09172 Infectious disease: viral
05169 Epstein-Barr virus infection
5707 (PSMD1)
09164 Neurodegenerative disease
05010 Alzheimer disease
5707 (PSMD1)
05012 Parkinson disease
5707 (PSMD1)
05014 Amyotrophic lateral sclerosis
5707 (PSMD1)
05016 Huntington disease
5707 (PSMD1)
05017 Spinocerebellar ataxia
5707 (PSMD1)
05020 Prion disease
5707 (PSMD1)
05022 Pathways of neurodegeneration - multiple diseases
5707 (PSMD1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03051 Proteasome [BR:
hsa03051
]
5707 (PSMD1)
Proteasome [BR:
hsa03051
]
Eukaryotic proteasome
Regulatory particles
PA700 (19S proteasome)
non-ATPase subunits
5707 (PSMD1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RPN2_N
RPN2_C
PC_rep
HEAT_2
HEAT_EZ
HEAT
Tim54
Motif
Other DBs
NCBI-GeneID:
5707
NCBI-ProteinID:
NP_002798
OMIM:
617842
HGNC:
9554
Ensembl:
ENSG00000173692
UniProt:
Q99460
Structure
PDB
PDBj
LinkDB
All DBs
Position
2:231056867..231172827
Genome browser
AA seq
953 aa
AA seq
DB search
MITSAAGIISLLDEDEPQLKEFALHKLNAVVNDFWAEISESVDKIEVLYEDEGFRSRQFA
ALVASKVFYHLGAFEESLNYALGAGDLFNVNDNSEYVETIIAKCIDHYTKQCVENADLPE
GEKKPIDQRLEGIVNKMFQRCLDDHKYKQAIGIALETRRLDVFEKTILESNDVPGMLAYS
LKLCMSLMQNKQFRNKVLRVLVKIYMNLEKPDFINVCQCLIFLDDPQAVSDILEKLVKED
NLLMAYQICFDLYESASQQFLSSVIQNLRTVGTPIASVPGSTNTGTVPGSEKDSDSMETE
EKTSSAFVGKTPEASPEPKDQTLKMIKILSGEMAIELHLQFLIRNNNTDLMILKNTKDAV
RNSVCHTATVIANSFMHCGTTSDQFLRDNLEWLARATNWAKFTATASLGVIHKGHEKEAL
QLMATYLPKDTSPGSAYQEGGGLYALGLIHANHGGDIIDYLLNQLKNASNDIVRHGGSLG
LGLAAMGTARQDVYDLLKTNLYQDDAVTGEAAGLALGLVMLGSKNAQAIEDMVGYAQETQ
HEKILRGLAVGIALVMYGRMEEADALIESLCRDKDPILRRSGMYTVAMAYCGSGNNKAIR
RLLHVAVSDVNDDVRRAAVESLGFILFRTPEQCPSVVSLLSESYNPHVRYGAAMALGICC
AGTGNKEAINLLEPMTNDPVNYVRQGALIASALIMIQQTEITCPKVNQFRQLYSKVINDK
HDDVMAKFGAILAQGILDAGGHNVTISLQSRTGHTHMPSVVGVLVFTQFWFWFPLSHFLS
LAYTPTCVIGLNKDLKMPKVQYKSNCKPSTFAYPAPLEVPKEKEKEKVSTAVLSITAKAK
KKEKEKEKKEEEKMEVDEAEKKEEKEKKKEPEPNFQLLDNPARVMPAQLKVLTMPETCRY
QPFKPLSIGGIIILKDTSEDIEELVEPVAAHGPKIEEEEQEPEPPEPFEYIDD
NT seq
2862 nt
NT seq
+upstream
nt +downstream
nt
atgatcacctcggccgctggaattatttctcttctggatgaagatgaaccacagcttaag
gaatttgcactacacaaattgaatgcagttgttaatgacttctgggcagaaatttccgag
tccgtagacaaaatagaggttttatacgaagatgaaggtttccggagtcggcagtttgca
gccttagtggcatctaaagtattttatcacctgggggcttttgaggagtctctgaattat
gctcttggagcaggggacctcttcaatgtcaatgataactctgaatatgtggaaactatt
atagcaaaatgcattgatcactacaccaaacaatgtgtggaaaatgcagatttgcctgaa
ggagaaaaaaaaccaattgaccagagattggaaggcatcgtaaataaaatgttccagcga
tgtctagatgatcacaagtataaacaggctattggcattgctctggagacacgaagactg
gacgtctttgaaaagaccatactggagtcgaatgatgtcccaggaatgttagcttatagc
cttaagctctgcatgtctttaatgcagaataaacagtttcggaataaagtactaagagtt
ctagttaaaatctacatgaacttggagaaacctgatttcatcaatgtttgtcagtgctta
attttcttagatgatcctcaggctgtgagtgatatcttagagaaactggtaaaggaagac
aacctcctgatggcatatcagatttgttttgatttgtatgaaagtgctagccagcagttt
ttgtcatctgtaatccagaatcttcgaactgttggcacccctattgcttctgtgcctgga
tccactaatacgggtactgttccgggatcagagaaagacagtgactcgatggaaacagaa
gaaaagacaagcagtgcatttgtaggaaagacaccagaagccagtccagagcctaaggac
cagactttgaaaatgattaaaattttaagtggtgaaatggctattgagttacatctgcag
ttcttaatacgaaacaataatacagacctcatgattctaaaaaacacaaaggatgcagta
cggaattctgtatgtcatactgcaaccgttatagcaaactcttttatgcactgtgggaca
accagtgaccagtttcttagagataatttggaatggttagccagagccactaactgggca
aaatttactgctacagccagtttgggtgtaattcataagggtcatgaaaaagaagcatta
cagttaatggcaacataccttcccaaggatacttctccaggatcagcctatcaggaaggt
ggaggtctctatgcactaggtcttattcatgccaatcatggtggtgatataattgactat
ctgcttaatcagcttaagaacgccagcaatgatatcgttagacacggtggcagtctgggc
cttggtttggcagccatgggaactgcacgtcaagatgtttatgatttgctaaaaacaaac
ctttatcaggatgatgcagtaacaggggaagcagctggcctggccctaggtttggttatg
ttgggctctaaaaatgctcaggctattgaggacatggttggttatgcacaagaaactcaa
catgagaagattctgcgtggtcttgcagttggcatagctttagtaatgtatgggaggatg
gaagaggctgatgctctcattgaatctctctgtcgtgacaaggacccaattcttcgaagg
tctggaatgtatactgtagccatggcttattgtggctctggtaacaacaaagcaattcga
cgcctgctacatgttgctgtaagtgatgttaatgatgatgtcaggagggcagcagtagaa
tcacttgggttcattctattcagaacccctgaacagtgcccaagtgttgtctctttgttg
tcagagagttacaaccctcatgtgcgctacggagctgcaatggccttggggatatgctgt
gctggtacaggaaacaaggaagccattaatttgctagaaccaatgacaaacgaccccgtg
aactacgtgaggcaaggggcactcatagcttcagctctcatcatgatccagcagactgaa
atcacttgtccaaaggtgaatcagttcagacagctgtattccaaagtcatcaatgataag
catgatgatgtcatggccaagtttggcgctattctggcccagggcatactggatgcaggt
ggtcataatgtcacaatctccttgcagtccaggactgggcatactcatatgccttctgtg
gttggcgtccttgtatttacccagttttggttctggtttcctctttcacacttcctgtca
ttggcttatacccctacctgtgtcattggccttaacaaggacttaaagatgccgaaagtt
cagtataaatcgaactgtaaaccatccacatttgcatatcctgcccctctggaagtacca
aaagaaaaagaaaaggaaaaggtttctactgctgtattatctataactgccaaggctaaa
aagaaggaaaaagaaaaggaaaaaaaggaggaggagaaaatggaagtggatgaggcagag
aaaaaggaggaaaaagagaagaaaaaagaacctgagccaaacttccagttattggataac
ccagcccgagttatgcctgcccagcttaaggtcctaaccatgccggagacctgtagatac
cagcctttcaaaccactctctattggaggcatcatcattctgaaggataccagtgaagac
attgaggagctggtggaacctgtggcagcacatggcccaaaaatcgaggaggaggaacaa
gagccagaacccccagaaccatttgagtatattgatgattaa
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integrated database retrieval system
