Homo sapiens (human): 5709
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Entry
5709 CDS
T01001
Symbol
PSMD3, P58, RPN3, S3, TSTA2
Name
(RefSeq) proteasome 26S subunit, non-ATPase 3
KO
K03033
26S proteasome regulatory subunit N3
Organism
hsa
Homo sapiens (human)
Pathway
hsa03050
Proteasome
hsa05010
Alzheimer disease
hsa05012
Parkinson disease
hsa05014
Amyotrophic lateral sclerosis
hsa05016
Huntington disease
hsa05017
Spinocerebellar ataxia
hsa05020
Prion disease
hsa05022
Pathways of neurodegeneration - multiple diseases
hsa05169
Epstein-Barr virus infection
Network
nt06460
Alzheimer disease
nt06461
Huntington disease
nt06463
Parkinson disease
nt06464
Amyotrophic lateral sclerosis
nt06465
Prion disease
nt06466
Pathways of neurodegeneration
Element
N01029
26S proteasome-mediated protein degradation
N01030
Mutation-caused aberrant SNCA to 26S proteasome-mediated protein degradation
N01060
Mutation-caused aberrant Abeta to 26S proteasome-mediated protein degradation
N01061
Mutation-caused aberrant Htt to 26S proteasome-mediated protein degradation
N01144
Mutation-caused aberrant SOD1 to 26S proteasome-mediated protein degradation
N01145
Mutation-inactivated VCP to 26S proteasome-mediated protein degradation
N01146
Mutation-inactivated UBQLN2 to 26S proteasome-mediated protein degradation
N01197
Scrapie conformation PrPSc to 26S proteasome-mediated protein degradation
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03050 Proteasome
5709 (PSMD3)
09160 Human Diseases
09172 Infectious disease: viral
05169 Epstein-Barr virus infection
5709 (PSMD3)
09164 Neurodegenerative disease
05010 Alzheimer disease
5709 (PSMD3)
05012 Parkinson disease
5709 (PSMD3)
05014 Amyotrophic lateral sclerosis
5709 (PSMD3)
05016 Huntington disease
5709 (PSMD3)
05017 Spinocerebellar ataxia
5709 (PSMD3)
05020 Prion disease
5709 (PSMD3)
05022 Pathways of neurodegeneration - multiple diseases
5709 (PSMD3)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03051 Proteasome [BR:
hsa03051
]
5709 (PSMD3)
Proteasome [BR:
hsa03051
]
Eukaryotic proteasome
Regulatory particles
PA700 (19S proteasome)
non-ATPase subunits
5709 (PSMD3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
TPR_PSMD3_N
Rpn3_C
PCI
CSN8_PSD8_EIF3K
TPR_2
Motif
Other DBs
NCBI-GeneID:
5709
NCBI-ProteinID:
NP_002800
OMIM:
617676
HGNC:
9560
Ensembl:
ENSG00000108344
UniProt:
O43242
Structure
PDB
PDBj
LinkDB
All DBs
Position
17:39980807..39997959
Genome browser
AA seq
534 aa
AA seq
DB search
MKQEGSARRRGADKAKPPPGGGEQEPPPPPAPQDVEMKEEAATGGGSTGEADGKTAAAAA
EHSQRELDTVTLEDIKEHVKQLEKAVSGKEPRFVLRALRMLPSTSRRLNHYVLYKAVQGF
FTSNNATRDFLLPFLEEPMDTEADLQFRPRTGKAASTPLLPEVEAYLQLLVVIFMMNSKR
YKEAQKISDDLMQKISTQNRRALDLVAAKCYYYHARVYEFLDKLDVVRSFLHARLRTATL
RHDADGQATLLNLLLRNYLHYSLYDQAEKLVSKSVFPEQANNNEWARYLYYTGRIKAIQL
EYSEARRTMTNALRKAPQHTAVGFKQTVHKLLIVVELLLGEIPDRLQFRQPSLKRSLMPY
FLLTQAVRTGNLAKFNQVLDQFGEKFQADGTYTLIIRLRHNVIKTGVRMISLSYSRISLA
DIAQKLQLDSPEDAEFIVAKAIRDGVIEASINHEKGYVQSKEMIDIYSTREPQLAFHQRI
SFCLDIHNMSVKAMRFPPKSYNKDLESAEERREREQQDLEFAKEMAEDDDDSFP
NT seq
1605 nt
NT seq
+upstream
nt +downstream
nt
atgaagcaggagggctcggcgcggcgccgcggcgcggacaaggcgaaaccgccgcccggc
ggaggagaacaagaacccccaccgccgccggccccccaggatgtggagatgaaagaggag
gcagcgacgggtggcgggtcgacgggggaggcagacggcaagacggcggcggcagcggct
gagcactcccagcgagagctggacacagtcaccttggaggacatcaaggagcacgtgaaa
cagctagagaaagcggtttcaggcaaggagccgagattcgtgctgcgggccctgcggatg
ctgccttccacatcacgccgcctcaaccactatgttctgtataaggctgtgcagggcttc
ttcacttcaaataatgccactcgagactttttgctccccttcctggaagagcccatggac
acagaggctgatttacagttccgtccccgcacgggaaaagctgcgtcgacacccctcctg
cctgaagtggaagcctatctccaactcctcgtggtcatcttcatgatgaacagcaagcgc
tacaaagaggcacagaagatctctgatgatctgatgcagaagatcagtactcagaaccgc
cgggccctagaccttgtagccgcaaagtgttactattatcacgcccgggtctatgagttc
ctggacaagctggatgtggtgcgcagcttcttgcatgctcggctccggacagctacgctt
cggcatgacgcagacgggcaggccaccctgttgaacctcctgctgcggaattacctacac
tacagcttgtacgaccaggctgagaagctggtgtccaagtctgtgttcccagagcaggcc
aacaacaatgagtgggccaggtacctctactacacagggcgaatcaaagccatccagctg
gagtactcagaggcccggagaacgatgaccaacgcccttcgcaaggcccctcagcacaca
gctgtcggcttcaaacagacggtgcacaagcttctcatcgtggtggagctgttgctgggg
gagatccctgaccggctgcagttccgccagccctccctcaagcgctcactcatgccctat
ttccttctgactcaagctgtcaggacaggaaacctagccaagttcaaccaggtcctggat
cagtttggggagaagtttcaagcagatgggacctacaccctaattatccggctgcggcac
aacgtgattaagacaggtgtacgcatgatcagcctctcctattcccgaatctccttggct
gacatcgcccagaagctgcagttggatagccccgaagatgcagagttcattgttgccaag
gccatccgggatggtgtcattgaggccagcatcaaccacgagaagggctatgtccaatcc
aaggagatgattgacatctattccacccgagagccccagctagccttccaccagcgcatc
tccttctgcctagatatccacaacatgtctgtcaaggccatgaggtttcctcccaaatcg
tacaacaaggacttggagtctgcagaggaacggcgtgagcgagaacagcaggacttggag
tttgccaaggagatggcagaagatgatgatgacagcttcccttga
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integrated database retrieval system
