KEGG   Homo sapiens (human): 5713
Entry
5713              CDS       T01001                                 

Gene name
PSMD7, MOV34, P40, Rpn8, S12
Definition
(RefSeq) proteasome 26S subunit, non-ATPase 7
  KO
K03038  26S proteasome regulatory subunit N8
Organism
hsa  Homo sapiens (human)
Pathway
hsa03050  Proteasome
hsa05010  Alzheimer disease
hsa05012  Parkinson disease
hsa05014  Amyotrophic lateral sclerosis
hsa05016  Huntington disease
hsa05017  Spinocerebellar ataxia
hsa05020  Prion disease
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05169  Epstein-Barr virus infection
Network
nt06420  Ubiquitin-proteasome system
nt06460  Alzheimer disease
nt06461  Huntington disease
nt06463  Parkinson disease
nt06464  Amyotrophic lateral sclerosis
nt06465  Prion disease
  Element
N01029  26S proteasome-mediated protein degradation
N01030  Mutation-caused aberrant SNCA to 26S proteasome-mediated protein degradation
N01060  Mutation-caused aberrant Abeta to 26S proteasome-mediated protein degradation
N01061  Mutation-caused aberrant Htt to 26S proteasome-mediated protein degradation
N01144  Mutation-caused aberrant SOD1 to 26S proteasome-mediated protein degradation
N01145  Mutation-inactivated VCP to 26S proteasome-mediated protein degradation
N01146  Mutation-inactivated UBQLN2 to 26S proteasome-mediated protein degradation
N01197  Scrapie conformation PrPSc to 26S proteasome-mediated protein degradation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03050 Proteasome
    5713 (PSMD7)
 09160 Human Diseases
  09172 Infectious disease: viral
   05169 Epstein-Barr virus infection
    5713 (PSMD7)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    5713 (PSMD7)
   05012 Parkinson disease
    5713 (PSMD7)
   05014 Amyotrophic lateral sclerosis
    5713 (PSMD7)
   05016 Huntington disease
    5713 (PSMD7)
   05017 Spinocerebellar ataxia
    5713 (PSMD7)
   05020 Prion disease
    5713 (PSMD7)
   05022 Pathways of neurodegeneration - multiple diseases
    5713 (PSMD7)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03051 Proteasome [BR:hsa03051]
    5713 (PSMD7)
Proteasome [BR:hsa03051]
 Eukaryotic proteasome
  Regulatory particles
   PA700 (19S proteasome)
    non-ATPase subunits
     5713 (PSMD7)
SSDB
Motif
Pfam: MitMem_reg JAB Connexin Coilin_N
Other DBs
NCBI-GeneID: 5713
NCBI-ProteinID: NP_002802
OMIM: 157970
HGNC: 9565
Ensembl: ENSG00000103035
Vega: OTTHUMG00000137601
Pharos: P51665(Tbio)
UniProt: P51665
LinkDB
Structure
PDB: 

Position
16q23.1
AA seq 324 aa
MPELAVQKVVVHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGSWQKKVLDVSNSFAVPFDE
DDKDDSVWFLDHDYLENMYGMFKKVNARERIVGWYHTGPKLHKNDIAINELMKRYCPNSV
LVIIDVKPKDLGLPTEAYISVEEVHDDGTPTSKTFEHVTSEIGAEEAEEVGVEHLLRDIK
DTTVGTLSQRITNQVHGLKGLNSKLLDIRSYLEKVATGKLPINHQIIYQLQDVFNLLPDV
SLQEFVKAFYLKTNDQMVVVYLASLIRSVVALHNLINNKIANRDAEKKEGQEKEESKKDR
KEDKEKDKDKEKSDVKKEEKKEKK
NT seq 975 nt   +upstreamnt  +downstreamnt
atgccggagctggcagtgcagaaggtggtggtccaccccctggtgctgctcagtgtggtg
gatcatttcaaccgaatcggcaaggttggaaaccagaagcgtgttgttggtgtgcttttg
gggtcatggcaaaagaaagtacttgatgtatcgaacagttttgcagttccttttgatgaa
gatgacaaagacgattctgtatggtttttagaccatgattatttggaaaacatgtatgga
atgtttaagaaagtcaatgccagggaaagaatagttggctggtaccacacaggccctaaa
ctacacaagaatgacattgccatcaacgaactcatgaaaagatactgtcctaattccgta
ttggtcatcattgatgtgaagccgaaggacctagggctgcctacagaagcgtacatttca
gtggaagaagtccatgatgatggaactccaacctcgaaaacatttgaacacgtgaccagt
gaaattggagcagaggaagctgaggaagttggagttgaacacttgttacgagatatcaaa
gacacgacggtgggcactctgtcccagcggatcacaaaccaggtccatggtttgaaggga
ctgaactccaagcttctggatatcaggagctacctggaaaaagtcgccacaggcaagctg
cccatcaaccaccagatcatctaccagctgcaggacgtcttcaacctgctgccagatgtc
agcctgcaggagttcgtcaaggccttttacctgaagaccaatgaccagatggtggtagtg
tacttggcctcgctgatccgttccgtggtcgccctgcacaacctcatcaacaacaagatt
gccaaccgggatgcagagaagaaagaagggcaggagaaagaagagagcaaaaaggatagg
aaagaggacaaggagaaagataaagataaggaaaagagtgatgtaaagaaagaggagaaa
aaggagaaaaagtaa

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