KEGG T01001: 5715

Homo sapiens (human): 5715

Entry

5715              CDS       T01001

Symbol

PSMD9, Rpn4, p27

Name

(RefSeq) proteasome 26S subunit, non-ATPase 9

K06693

26S proteasome regulatory subunit N4

Organism

hsa Homo sapiens (human)

Pathway

hsa03050

Proteasome

hsa05010

Alzheimer disease

hsa05012

Parkinson disease

hsa05014

Amyotrophic lateral sclerosis

hsa05016

Huntington disease

hsa05017

Spinocerebellar ataxia

hsa05020

Prion disease

hsa05022

Pathways of neurodegeneration - multiple diseases

Network

nt06460  Alzheimer disease
nt06461  Huntington disease
nt06463  Parkinson disease
nt06464  Amyotrophic lateral sclerosis
nt06465  Prion disease
nt06466  Pathways of neurodegeneration

Element

N01029

26S proteasome-mediated protein degradation

N01030

Mutation-caused aberrant SNCA to 26S proteasome-mediated protein degradation

N01060

Mutation-caused aberrant Abeta to 26S proteasome-mediated protein degradation

N01061

Mutation-caused aberrant Htt to 26S proteasome-mediated protein degradation

N01144

Mutation-caused aberrant SOD1 to 26S proteasome-mediated protein degradation

N01145

Mutation-inactivated VCP to 26S proteasome-mediated protein degradation

N01146

Mutation-inactivated UBQLN2 to 26S proteasome-mediated protein degradation

N01197

Scrapie conformation PrPSc to 26S proteasome-mediated protein degradation

Brite

KEGG Orthology (KO) [BR:hsa00001]
09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03050 Proteasome
    5715 (PSMD9)
09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    5715 (PSMD9)
   05012 Parkinson disease
    5715 (PSMD9)
   05014 Amyotrophic lateral sclerosis
    5715 (PSMD9)
   05016 Huntington disease
    5715 (PSMD9)
   05017 Spinocerebellar ataxia
    5715 (PSMD9)
   05020 Prion disease
    5715 (PSMD9)
   05022 Pathways of neurodegeneration - multiple diseases
    5715 (PSMD9)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03051 Proteasome [BR:hsa03051]
    5715 (PSMD9)
Proteasome [BR:hsa03051]
Eukaryotic proteasome
  Regulatory particles
   PA700 (19S proteasome)
    non-ATPase subunits
     5715 (PSMD9)

SSDB

Motif

Pfam:

Nas2_N PDZ_6 PDZ_2 PDZ GRASP55_65

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

UniProt:

LinkDB

Position

12:121888790..121918297

AA seq 223 aa
MSDEEARQSGGSSQAGVVTVSDVQELMRRKEEIEAQIKANYDVLESQKGIGMNEPLVDCE
GYPRSDVDLYQVRTARHNIICLQNDHKAVMKQVEEALHQLHARDKEKQARDMAEAHKEAM
SRKLGQSESQGPPRAFAKVNSISPGSPASIAGLQVDDEIVEFGSVNTQNFQSLHNIGSVV
QHSEGKPLNVTVIRRGEKHQLRLVPTRWAGKGLLGCNIIPLQR

NT seq 672 nt +upstreamnt +downstreamnt
atgtccgacgaggaagcgaggcagagcggaggctcctcgcaggccggcgtcgtgactgtc
agcgacgtccaggagctgatgcggcgcaaggaggagatagaagcgcagatcaaggccaac
tatgacgtgctggaaagccaaaaaggcattgggatgaacgagccgctggtggactgtgag
ggctacccccggtcagacgtggacctgtaccaagtccgcaccgccaggcacaacatcata
tgcctgcagaatgatcacaaggcagtgatgaagcaggtggaggaggccctgcaccagctg
cacgctcgcgacaaggagaagcaggcccgggacatggctgaggcccacaaagaggccatg
agccgcaaactgggtcagagtgagagccagggccctccacgggccttcgccaaagtgaac
agcatcagccccggctccccagccagcatcgcgggtctgcaagtggatgatgagattgtg
gagttcggctctgtgaacacccagaacttccagtcactgcataacattggcagtgtggtg
cagcacagtgaggggaagcccctgaatgtgacagtgatccgcaggggggaaaaacaccag
cttagacttgttccaacacgctgggcaggaaaaggactgctgggctgcaacattattcct
ctgcaaagatga

DBGET integrated database retrieval system