KEGG T01001: 5861

Homo sapiens (human): 5861

Entry

5861              CDS       T01001

Symbol

RAB1A, RAB1, YPT1

Name

(RefSeq) RAB1A, member RAS oncogene family

K07874

Ras-related protein Rab-1A

Organism

hsa Homo sapiens (human)

Pathway

hsa04140

Autophagy - animal

hsa05014

Amyotrophic lateral sclerosis

hsa05022

Pathways of neurodegeneration - multiple diseases

hsa05130

Pathogenic Escherichia coli infection

hsa05134

Legionellosis

Network

nt06180  Pathogenic Escherichia coli
nt06464  Amyotrophic lateral sclerosis
nt06466  Pathways of neurodegeneration
nt06532  Autophagy

Element

N01142

C9orf72-mediated autophagy initiation

N01143

Mutation-inactivated C9orf72 to C9orf72-mediated autophagy initiation

N01291

TRAPPI-RAB1 signaling pathway

N01292

Escherichia EspG to RAB1 signaling pathway

Brite

KEGG Orthology (KO) [BR:hsa00001]
09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    5861 (RAB1A)
09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    5861 (RAB1A)
   05134 Legionellosis
    5861 (RAB1A)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    5861 (RAB1A)
   05022 Pathways of neurodegeneration - multiple diseases
    5861 (RAB1A)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    5861 (RAB1A)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    5861 (RAB1A)
   04031 GTP-binding proteins [BR:hsa04031]
    5861 (RAB1A)
Membrane trafficking [BR:hsa04131]
Endoplasmic reticulum (ER) - Golgi transport
  Forward pathways
   Rab GTPases
    5861 (RAB1A)
Autophagy
  Other autophagy associated proteins
    5861 (RAB1A)
Exosome [BR:hsa04147]
Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   5861 (RAB1A)
  Exosomal proteins of other body fluids (saliva and urine)
   5861 (RAB1A)
  Exosomal proteins of colorectal cancer cells
   5861 (RAB1A)
GTP-binding proteins [BR:hsa04031]
Small (monomeric) G-proteins
  Rab Family
   Rab1/35 [OT]
    5861 (RAB1A)

SSDB

Motif

Pfam:

Ras Roc Arf GTP_EFTU RsgA_GTPase MMR_HSR1 Gtr1_RagA SRPRB FeoB_N AAA ABC_tran AAA_7 PduV-EutP AAA_29 LANC_like AAA_16 AAA_22 Septin AAA_5 Dioxygenase_N CRAL_TRIO_2 TniB

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

UniProt:

Structure

LinkDB

Position

2:complement(65086854..65130106)

AA seq 205 aa
MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
KLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKL
LVGNKCDLTTKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGA
TAGGAEKSNVKIQSTPVKQSGGGCC

NT seq 618 nt +upstreamnt +downstreamnt
atgtccagcatgaatcccgaatatgattatttattcaagttacttctgattggcgactca
ggggttggaaagtcttgccttcttcttaggtttgcagatgatacatatacagaaagctac
atcagcacaattggtgtggatttcaaaataagaactatagagttagacgggaaaacaatc
aagcttcaaatatgggacacagcaggccaggaaagatttcgaacaatcacctccagttat
tacagaggagcccatggcatcatagttgtgtatgatgtgacagatcaggagtccttcaat
aatgttaaacagtggctgcaggaaatagatcgttatgccagtgaaaatgtcaacaaattg
ttggtagggaacaaatgtgatctgaccacaaagaaagtagtagactacacaacagcgaag
gaatttgctgattcccttggaattccgtttttggaaaccagtgctaagaatgcaacgaat
gtagaacagtctttcatgacgatggcagctgagattaaaaagcgaatgggtcccggagca
acagctggtggtgctgagaagtccaatgttaaaattcagagcactccagtcaagcagtca
ggtggaggttgctgctaa

Homo sapiens (human): 81876

Entry

81876             CDS       T01001

Symbol

RAB1B

Name

(RefSeq) RAB1B, member RAS oncogene family

K07875

Ras-related protein Rab-1B

Organism

hsa Homo sapiens (human)

Pathway

hsa05134

Legionellosis

Network

nt06180 Pathogenic Escherichia coli

Element

N01291

TRAPPI-RAB1 signaling pathway

N01292

Escherichia EspG to RAB1 signaling pathway

Brite

KEGG Orthology (KO) [BR:hsa00001]
09160 Human Diseases
  09171 Infectious disease: bacterial
   05134 Legionellosis
    81876 (RAB1B)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    81876 (RAB1B)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    81876 (RAB1B)
   04031 GTP-binding proteins [BR:hsa04031]
    81876 (RAB1B)
Membrane trafficking [BR:hsa04131]
Endoplasmic reticulum (ER) - Golgi transport
  Forward pathways
   Rab GTPases
    81876 (RAB1B)
Autophagy
  Other autophagy associated proteins
    81876 (RAB1B)
Exosome [BR:hsa04147]
Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   81876 (RAB1B)
  Exosomal proteins of other body fluids (saliva and urine)
   81876 (RAB1B)
  Exosomal proteins of colorectal cancer cells
   81876 (RAB1B)
  Exosomal proteins of bladder cancer cells
   81876 (RAB1B)
GTP-binding proteins [BR:hsa04031]
Small (monomeric) G-proteins
  Rab Family
   Rab1/35 [OT]
    81876 (RAB1B)

SSDB

Motif

Pfam:

Ras Roc Arf GTP_EFTU MMR_HSR1 RsgA_GTPase SRPRB Gtr1_RagA AAA FeoB_N ABC_tran AAA_7 AAA_22 AAA_29 Septin AAA_16 AAA_5 PduV-EutP LepB_N DUF815

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

UniProt:

Structure

LinkDB

Position

11:66268639..66277492

AA seq 201 aa
MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQ
IWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVG
NKSDLTTKKVVDNTTAKEFADSLGIPFLETSAKNATNVEQAFMTMAAEIKKRMGPGAASG
GERPNLKIDSTPVKPAGGGCC

NT seq 606 nt +upstreamnt +downstreamnt
atgaaccccgaatatgactacctgtttaagctgcttttgattggcgactcaggcgtgggc
aagtcatgcctgctcctgcggtttgctgatgacacgtacacagagagctacatcagcacc
atcggggtggacttcaagatccgaaccatcgagctggatggcaaaactatcaaacttcag
atctgggacacagcgggccaggaacggttccggaccatcacttccagctactaccggggg
gctcatggcatcatcgtggtgtatgacgtcactgaccaggaatcctacgccaacgtgaag
cagtggctgcaggagattgaccgctatgccagcgagaacgtcaataagctcctggtgggc
aacaagagcgacctcaccaccaagaaggtggtggacaacaccacagccaaggagtttgca
gactctctgggcatccccttcttggagacgagcgccaagaatgccaccaatgtcgagcag
gcgttcatgaccatggctgctgaaatcaaaaagcggatggggcctggagcagcctctggg
ggcgagcggcccaatctcaagatcgacagcacccctgtaaagccggctggcggtggctgt
tgctag

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