Homo sapiens (human): 5868
Help
Entry
5868 CDS
T01001
Symbol
RAB5A, RAB5
Name
(RefSeq) RAB5A, member RAS oncogene family
KO
K07887
Ras-related protein Rab-5A
Organism
hsa
Homo sapiens (human)
Pathway
hsa04014
Ras signaling pathway
hsa04137
Mitophagy - animal
hsa04144
Endocytosis
hsa04145
Phagosome
hsa04148
Efferocytosis
hsa04962
Vasopressin-regulated water reabsorption
hsa05014
Amyotrophic lateral sclerosis
hsa05022
Pathways of neurodegeneration - multiple diseases
hsa05132
Salmonella infection
hsa05146
Amoebiasis
hsa05152
Tuberculosis
Network
nt06181
Salmonella
nt06536
Mitophagy
Element
N01302
Early endosomal fusion
N01303
Salmonella SopB to Early endosomal fusion
N01760
Endosomal Rab cycles
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
5868 (RAB5A)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
5868 (RAB5A)
04145 Phagosome
5868 (RAB5A)
04137 Mitophagy - animal
5868 (RAB5A)
04148 Efferocytosis
5868 (RAB5A)
09150 Organismal Systems
09155 Excretory system
04962 Vasopressin-regulated water reabsorption
5868 (RAB5A)
09160 Human Diseases
09171 Infectious disease: bacterial
05132 Salmonella infection
5868 (RAB5A)
05152 Tuberculosis
5868 (RAB5A)
09174 Infectious disease: parasitic
05146 Amoebiasis
5868 (RAB5A)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
5868 (RAB5A)
05022 Pathways of neurodegeneration - multiple diseases
5868 (RAB5A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
5868 (RAB5A)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hsa04147
]
5868 (RAB5A)
04031 GTP-binding proteins [BR:
hsa04031
]
5868 (RAB5A)
Membrane trafficking [BR:
hsa04131
]
Endocytosis
Rab GTPases and associated proteins
Rab GTPases
5868 (RAB5A)
Endosome - Lysosome transport
5868 (RAB5A)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
5868 (RAB5A)
Exosomal proteins of other body fluids (saliva and urine)
5868 (RAB5A)
Exosomal proteins of colorectal cancer cells
5868 (RAB5A)
Exosomal proteins of bladder cancer cells
5868 (RAB5A)
GTP-binding proteins [BR:
hsa04031
]
Small (monomeric) G-proteins
Rab Family
Rab5/17/22/31 [OT]
5868 (RAB5A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ras
Roc
Arf
GTP_EFTU
Gtr1_RagA
MMR_HSR1
RsgA_GTPase
AAA_16
MCR_beta
BrnT_toxin
Motif
Other DBs
NCBI-GeneID:
5868
NCBI-ProteinID:
NP_004153
OMIM:
179512
HGNC:
9783
Ensembl:
ENSG00000144566
UniProt:
P20339
Structure
PDB
LinkDB
All DBs
Position
3:19947097..19985175
Genome browser
AA seq
215 aa
AA seq
DB search
MASRGATRPNGPNTGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQ
TVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQR
QASPNIVIALSGNKADLANKRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAKK
LPKNEPQNPGANSARGRGVDLTEPTQPTRNQCCSN
NT seq
648 nt
NT seq
+upstream
nt +downstream
nt
atggctagtcgaggcgcaacaagacccaacgggccaaatacgggaaataaaatatgccag
ttcaaactagtacttctgggagagtccgctgttggcaaatcaagcctagtgcttcgtttt
gtgaaaggccaatttcatgaatttcaagagagtaccattggggctgcttttctaacccaa
actgtatgtcttgatgacactacagtaaagtttgaaatatgggatacagctggtcaagaa
cgataccatagcctagcaccaatgtactacagaggagcacaagcagccatagttgtatat
gatatcacaaatgaggagtcctttgcaagagcaaaaaattgggttaaagaacttcagagg
caagcaagtcctaacattgtaatagctttatcgggaaacaaggccgacctagcaaataaa
agagcagtagatttccaggaagcacagtcctatgcagatgacaatagtttattattcatg
gagacatccgctaaaacatcaatgaatgtaaatgaaatattcatggcaatagctaaaaaa
ttgccaaagaatgaaccacaaaatccaggagcaaattctgccagaggaagaggagtagac
cttaccgaacccacacaaccaaccaggaatcagtgttgtagtaactaa
DBGET
integrated database retrieval system