KEGG   NETWORK: N01303
Entry
N01303                      Network                                
Name
Salmonella SopB to Early endosomal fusion
Definition
SopB -> RAB5 -> PIK3C3 -> PI3P
  Expanded
K13085 -> (5868,5869,5878) -> 5289 -> C04549
Class
nt06125 Membrane trafficking (bacteria)
Type
Pathogen
Pathway
hsa05132  Salmonella infection
Disease
H00113  Salmonellosis
Gene
5868  RAB5A; RAB5A, member RAS oncogene family
5869  RAB5B; RAB5B, member RAS oncogene family
5878  RAB5C; RAB5C, member RAS oncogene family
5289  PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3
Perturbant
K13085 (SopB)  ipgD; phosphatidylinositol-4,5-bisphosphate 4-phosphatase
Metabolite
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
Reference
  Authors
Mallo GV, Espina M, Smith AC, Terebiznik MR, Aleman A, Finlay BB, Rameh LE, Grinstein S, Brumell JH
  Title
SopB promotes phosphatidylinositol 3-phosphate formation on Salmonella vacuoles by recruiting Rab5 and Vps34.
  Journal
J Cell Biol 182:741-52 (2008)
DOI:10.1083/jcb.200804131
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