KEGG   Homo sapiens (human): 5984
Entry
5984              CDS       T01001                                 
Symbol
RFC4, A1, MRMNS, RFC37
Name
(RefSeq) replication factor C subunit 4
  KO
K10755  replication factor C subunit 2/4
Organism
hsa  Homo sapiens (human)
Pathway
hsa03030  DNA replication
hsa03410  Base excision repair
hsa03420  Nucleotide excision repair
hsa03430  Mismatch repair
Network
nt06503  Mismatch repair
nt06504  Base excision repair
nt06506  Double-strand break repair
nt06509  DNA replication
  Element
N01432  Mismatch repair
N01436  Long patch BER
N01452  Homologous recombination
N01471  Origin unwinding and elongation
Disease
H02840  Morimoto-Ryu-Malicdan neuromuscular syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    5984 (RFC4)
   03410 Base excision repair
    5984 (RFC4)
   03420 Nucleotide excision repair
    5984 (RFC4)
   03430 Mismatch repair
    5984 (RFC4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:hsa03032]
    5984 (RFC4)
   03036 Chromosome and associated proteins [BR:hsa03036]
    5984 (RFC4)
   03400 DNA repair and recombination proteins [BR:hsa03400]
    5984 (RFC4)
DNA replication proteins [BR:hsa03032]
 Eukaryotic type
  DNA Replication Elongation Factors
   RFC (replication factor C)
    5984 (RFC4)
  DNA Replication Termination Factors
   ELG1-RFC complex
    5984 (RFC4)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Sister chromatid cohesion proteins
   CTF18-RFC complex
    5984 (RFC4)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   MMR (mismatch excision repair)
    RFC (replication factor C)
     5984 (RFC4)
  Check point factors
   HRAD17(Rad24)-RFC complex
    5984 (RFC4)
SSDB
Motif
Pfam: Rep_fac_C AAA DNA_pol3_delta2 RCF1-5-like_lid Rad17 AAA_assoc_2 DUF815 AAA_16 AAA_30 AAA_22 AAA_11 AAA_24 Mg_chelatase AAA_28 SLFN-g3_helicase RuvB_N Gp44_lid AAA_19 AAA_5 ResIII TIP49_C Viral_helicase1 AAA_7 DUF6096
Other DBs
NCBI-GeneID: 5984
NCBI-ProteinID: NP_002907
OMIM: 102577
HGNC: 9972
Ensembl: ENSG00000163918
UniProt: P35249
Structure
LinkDB
Position
3:complement(186789900..186806482)
AA seq 363 aa
MQAFLKGTSISTKPPLTKDRGVAASAGSSGENKKAKPVPWVEKYRPKCVDEVAFQEEVVA
VLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELFGPELFRLRVLELNASDERGIQVVR
EKVKNFAQLTVSGSRSDGKPCPPFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLIC
NYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRK
AITFLQSATRLTGGKEITEKVITDIAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLIDEG
HAATQLVNQLHDVVVENNLSDKQKSIITEKLAEVDKCLADGADEHLQLISLCATVMQQLS
QNC
NT seq 1092 nt   +upstreamnt  +downstreamnt
atgcaagcatttcttaaaggtacatccatcagtactaaacccccgctgaccaaggatcga
ggagtagctgccagtgcgggaagtagcggagagaacaagaaagccaaacccgttccctgg
gtggaaaaatatcgcccaaaatgtgtggatgaagttgctttccaggaagaagtggttgca
gtgctgaaaaaatctttagaaggagcagatcttcctaatctcttgttttacggaccacct
ggaactggaaaaacatccactattttggcagcagctagagaactctttgggcctgaactt
ttccgattaagagttcttgagttaaatgcatctgatgaacgtggaatacaagtagttcga
gagaaagtgaaaaattttgctcaattaactgtgtcaggaagtcgctcagatgggaagccg
tgtccgccttttaagattgtgattctggatgaagcagattctatgacctcagctgctcag
gcagctttaagacgtaccatggagaaggagtcgaaaaccacccgattctgtcttatctgt
aactatgtcagtcgaataattgaacccctgacctctagatgttcaaaattccgcttcaag
cctctgtcagataaaattcaacagcagcgattactagacattgccaagaaggaaaatgtc
aaaattagtgatgagggaatagcttatcttgttaaagtgtcagaaggagacttaagaaaa
gccattacatttcttcaaagcgctactcgattaacaggtggaaaggagatcacagagaaa
gtgattacagacattgccggggtaataccagctgagaaaattgatggagtatttgctgcc
tgtcagagtggctcttttgacaaactagaagctgtggtcaaggatttaatagatgagggt
catgcagcaactcagctcgtcaatcaactccatgatgtggttgtagaaaataacttatct
gataaacagaagtctattatcacagaaaaacttgccgaagttgacaaatgcctagcagat
ggtgctgatgaacatttgcaactcatcagcctttgtgcaactgtgatgcagcagttatct
cagaattgttaa

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