Homo sapiens (human): 623 Help Entry 623               CDS       T01001                                  Symbol BDKRB1, B1BKR, B1R, BKB1R, BKR1, BRADYB1 Name (RefSeq) bradykinin receptor B1   KO K03915   bradykinin receptor B1 Organism hsa  Homo sapiens (human) Pathway hsa04020   Calcium signaling pathway hsa04080   Neuroactive ligand-receptor interaction hsa04610   Complement and coagulation cascades hsa04750   Inflammatory mediator regulation of TRP channels hsa04810   Regulation of actin cytoskeleton hsa05200   Pathways in cancer Network nt06514  Coagulation cascade nt06528  Calcium signaling   Element N01517   Kallikrein-kinin system, HMWK to bradykinin N01640   GPCR-PLCB-ITPR signaling pathway Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04020 Calcium signaling pathway     623 (BDKRB1)   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     623 (BDKRB1)  09140 Cellular Processes   09142 Cell motility    04810 Regulation of actin cytoskeleton     623 (BDKRB1)  09150 Organismal Systems   09151 Immune system    04610 Complement and coagulation cascades     623 (BDKRB1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     623 (BDKRB1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     623 (BDKRB1)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     623 (BDKRB1) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Peptide    Bradykinin     623 (BDKRB1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  7tm_1 7TM_GPCR_Srw 7TM_GPCR_Srx 7TM_GPCR_Srv Motif Other DBs NCBI-GeneID:  623 NCBI-ProteinID:  NP_000701 OMIM:  600337 HGNC:  1029 Ensembl:  ENSG00000100739 UniProt:  P46663 Structure PDBPDBj LinkDB All DBs Position 14:96256210..96264763 Genome browser AA seq 353 aa AA seqDB search MASSWPPLELQSSNQSQLFPQNATACDNAPEAWDLLHRVLPTFIISICFFGLLGNLFVLL VFLLPRRQLNVAEIYLANLAASDLVFVLGLPFWAENIWNQFNWPFGALLCRVINGVIKAN LFISIFLVVAISQDRYRVLVHPMASRRQQRRRQARVTCVLIWVVGGLLSIPTFLLRSIQA VPDLNITACILLLPHEAWHFARIVELNILGFLLPLAAIVFFNYHILASLRTREEVSRTRC GGRKDSKTTALILTLVVAFLVCWAPYHFFAFLEFLFQVQAVRGCFWEDFIDLGLQLANFF AFTNSSLNPVIYVFVGRLFRTKVWELYKQCTPKSLAPISSSHRKEIFQLFWRN NT seq 1062 nt NT seq  +upstreamnt  +downstreamnt atggcatcatcctggccccctctagagctccaatcctccaaccagagccagctcttccct caaaatgctacggcctgtgacaatgctccagaagcctgggacctgctgcacagagtgctg ccaacatttatcatctccatctgtttcttcggcctcctagggaacctttttgtcctgttg gtcttcctcctgccccggcggcaactgaacgtggcagaaatctacctggccaacctggca gcctctgatctggtgtttgtcttgggcttgcccttctgggcagagaatatctggaaccag tttaactggcctttcggagccctcctctgccgtgtcatcaacggggtcatcaaggccaat ttgttcatcagcatcttcctggtggtggccatcagccaggaccgctaccgcgtgctggtg caccctatggccagccggaggcagcagcggcggaggcaggcccgggtcacctgcgtgctc atctgggttgtggggggcctcttgagcatccccacattcctgctgcgatccatccaagcc gtcccagatctgaacatcaccgcctgcatcctgctcctcccccatgaggcctggcacttt gcaaggattgtggagttaaatattctgggtttcctcctaccactggctgcgatcgtcttc ttcaactaccacatcctggcctccctgcgaacgcgggaggaggtcagcaggacaaggtgc gggggccgcaaggatagcaagaccacagcgctgatcctcacgctcgtggttgccttcctg gtctgctgggccccttaccacttctttgccttcctggaattcttattccaggtgcaagca gtccgaggctgcttttgggaggacttcattgacctgggcctgcaattggccaacttcttt gccttcactaacagctccctgaatccagtaatttatgtctttgtgggccggctcttcagg accaaggtctgggaactttataaacaatgcacccctaaaagtcttgctccaatatcttca tcccataggaaagaaatcttccaacttttctggcggaattaa

Homo sapiens (human): 624 Help Entry 624               CDS       T01001                                  Symbol BDKRB2, B2R, BK-2, BK2, BKR2, BRB2 Name (RefSeq) bradykinin receptor B2   KO K03916   bradykinin receptor B2 Organism hsa  Homo sapiens (human) Pathway hsa04020   Calcium signaling pathway hsa04022   cGMP-PKG signaling pathway hsa04071   Sphingolipid signaling pathway hsa04080   Neuroactive ligand-receptor interaction hsa04610   Complement and coagulation cascades hsa04750   Inflammatory mediator regulation of TRP channels hsa04810   Regulation of actin cytoskeleton hsa04961   Endocrine and other factor-regulated calcium reabsorption hsa05142   Chagas disease hsa05200   Pathways in cancer Network nt06514  Coagulation cascade nt06528  Calcium signaling   Element N01517   Kallikrein-kinin system, HMWK to bradykinin N01640   GPCR-PLCB-ITPR signaling pathway Drug target Deltibant:  D03677 Deucrictibant:  D12618 Icatibant:  D04492<JP/US> Labradimil:  D08937 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04020 Calcium signaling pathway     624 (BDKRB2)    04071 Sphingolipid signaling pathway     624 (BDKRB2)    04022 cGMP-PKG signaling pathway     624 (BDKRB2)   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     624 (BDKRB2)  09140 Cellular Processes   09142 Cell motility    04810 Regulation of actin cytoskeleton     624 (BDKRB2)  09150 Organismal Systems   09151 Immune system    04610 Complement and coagulation cascades     624 (BDKRB2)   09155 Excretory system    04961 Endocrine and other factor-regulated calcium reabsorption     624 (BDKRB2)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     624 (BDKRB2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     624 (BDKRB2)   09174 Infectious disease: parasitic    05142 Chagas disease     624 (BDKRB2)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     624 (BDKRB2) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Peptide    Bradykinin     624 (BDKRB2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  7tm_1 DUF898 zf-LITAF-like Motif Other DBs NCBI-GeneID:  624 NCBI-ProteinID:  NP_000614 OMIM:  113503 HGNC:  1030 Ensembl:  ENSG00000168398 UniProt:  P30411 Structure PDBPDBj LinkDB All DBs Position 14:96204839..96244164 Genome browser AA seq 391 aa AA seqDB search MFSPWKISMFLSVREDSVPTTASFSADMLNVTLQGPTLNGTFAQSKCPQVEWLGWLNTIQ PPFLWVLFVLATLENIFVLSVFCLHKSSCTVAEIYLGNLAAADLILACGLPFWAITISNN FDWLFGETLCRVVNAIISMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLV IWGCTLLLSSPMLVFRTMKEYSDEGHNVTACVISYPSLIWEVFTNMLLNVVGFLLPLSVI TFCTMQIMQVLRNNEMQKFKEIQTERRATVLVLVVLLLFIICWLPFQISTFLDTLHRLGI LSSCQDERIIDVITQIASFMAYSNSCLNPLVYVIVGKRFRKKSWEVYQGVCQKGGCRSEP IQMENSMGTLRTSISVERQIHKLQDWAGSRQ NT seq 1176 nt NT seq  +upstreamnt  +downstreamnt atgttctctccctggaagatatcaatgtttctgtctgttcgtgaggactccgtgcccacc acggcctctttcagcgccgacatgctcaatgtcaccttgcaagggcccactcttaacggg acctttgcccagagcaaatgcccccaagtggagtggctgggctggctcaacaccatccag ccccccttcctctgggtgctgttcgtgctggccaccctagagaacatctttgtcctcagc gtcttctgcctgcacaagagcagctgcacggtggcagagatctacctggggaacctggcc gcagcagacctgatcctggcctgcgggctgcccttctgggccatcaccatctccaacaac ttcgactggctctttggggagacgctctgccgcgtggtgaatgccattatctccatgaac ctgtacagcagcatctgtttcctgatgctggtgagcatcgaccgctacctggccctggtg aaaaccatgtccatgggccggatgcgcggcgtgcgctgggccaagctctacagcttggtg atctgggggtgtacgctgctcctgagctcacccatgctggtgttccggaccatgaaggag tacagcgatgagggccacaacgtcaccgcttgtgtcatcagctacccatccctcatctgg gaagtgttcaccaacatgctcctgaatgtcgtgggcttcctgctgcccctgagtgtcatc accttctgcacgatgcagatcatgcaggtgctgcggaacaacgagatgcagaagttcaag gagatccagacagagaggagggccacggtgctagtcctggttgtgctgctgctattcatc atctgctggctgcccttccagatcagcaccttcctggatacgctgcatcgcctcggcatc ctctccagctgccaggacgagcgcatcatcgatgtaatcacacagatcgcctccttcatg gcctacagcaacagctgcctcaacccactggtgtacgtgatcgtgggcaagcgcttccga aagaagtcttgggaggtgtaccagggagtgtgccagaaagggggctgcaggtcagaaccc attcagatggagaactccatgggcacactgcggacctccatctccgtggaacgccagatt cacaaactgcaggactgggcagggagcagacagtga

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