KEGG   Homo sapiens (human): 6500
Entry
6500              CDS       T01001                                 
Symbol
SKP1, EMC19, OCP-II, OCP2, SKP1A, TCEB1L, p19A
Name
(RefSeq) S-phase kinase associated protein 1
  KO
K03094  S-phase kinase-associated protein 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa03083  Polycomb repressive complex
hsa04110  Cell cycle
hsa04114  Oocyte meiosis
hsa04120  Ubiquitin mediated proteolysis
hsa04141  Protein processing in endoplasmic reticulum
hsa04310  Wnt signaling pathway
hsa04350  TGF-beta signaling pathway
hsa04710  Circadian rhythm
hsa05131  Shigellosis
hsa05132  Salmonella infection
hsa05170  Human immunodeficiency virus 1 infection
hsa05200  Pathways in cancer
Network
nt06165  Epstein-Barr virus (EBV)
nt06166  Human papillomavirus (HPV)
nt06181  Salmonella
nt06182  Shigella
nt06230  Cell cycle (cancer)
nt06261  Gastric cancer
nt06267  Small cell lung cancer
nt06272  Prostate cancer
nt06516  TNF signaling
nt06523  Epigenetic regulation by Polycomb complexes
  Element
N00091  p27-Cell cycle G1/S
N00092  Amplified MYC to p27-cell cycle G1/S
N00942  Shigella OspG to TNF-NFKB signaling pathway
N01117  Salmonella GogB to TNF-NFKB signaling pathway
N01586  Activation of PRC2.2 by ubiquitination of H2AK119
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    6500 (SKP1)
   04120 Ubiquitin mediated proteolysis
    6500 (SKP1)
  09126 Chromosome
   03083 Polycomb repressive complex
    6500 (SKP1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    6500 (SKP1)
   04350 TGF-beta signaling pathway
    6500 (SKP1)
 09150 Organismal Systems
  09159 Environmental adaptation
   04710 Circadian rhythm
    6500 (SKP1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    6500 (SKP1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    6500 (SKP1)
  09171 Infectious disease: bacterial
   05131 Shigellosis
    6500 (SKP1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    6500 (SKP1)
   04121 Ubiquitin system [BR:hsa04121]
    6500 (SKP1)
   03036 Chromosome and associated proteins [BR:hsa03036]
    6500 (SKP1)
Membrane trafficking [BR:hsa04131]
 Endosome - Lysosome transport
  Acidification regulators
   RAVE complex
    6500 (SKP1)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   SCF complex
    Adaptor protein
     6500 (SKP1)
   Cul7 complex
     6500 (SKP1)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Histone modification proteins
   Polycomb repressive complex (PRC) and associated proteins
    Noncanonical PRC1 (PRC1.1)
     6500 (SKP1)
  Centromeric chromatin formation proteins
   Kinetochore proteins
    CBF3 complex
     6500 (SKP1)
SSDB
Motif
Pfam: Skp1 Skp1_POZ
Other DBs
NCBI-GeneID: 6500
NCBI-ProteinID: NP_733779
OMIM: 601434
HGNC: 10899
Ensembl: ENSG00000113558
UniProt: P63208
Structure
LinkDB
Position
5:complement(134148935..134176950)
AA seq 163 aa
MPSIKLQSSDGEIFEVDVEIAKQSVTIKTMLEDLGMDDEGDDDPVPLPNVNAAILKKVIQ
WCTHHKDDPPPPEDDENKEKRTDDIPVWDQEFLKVDQGTLFELILAANYLDIKGLLDVTC
KTVANMIKGKTPEEIRKTFNIKNDFTEEEEAQVRKENQWCEEK
NT seq 492 nt   +upstreamnt  +downstreamnt
atgccttcaattaagttgcagagttctgatggagagatatttgaagttgatgtggaaatt
gccaaacaatctgtgactattaagaccatgttggaagatttgggaatggatgatgaagga
gatgatgacccagttcctctaccaaatgtgaatgcagcaatattaaaaaaggtcattcag
tggtgcacccaccacaaggatgaccctcctcctcctgaagatgatgagaacaaagaaaag
cgaacagatgatatccctgtttgggaccaagaattcctgaaagttgaccaaggaacactt
tttgaactcattctggctgcaaactacttagacatcaaaggtttgcttgatgttacatgc
aagactgttgccaatatgatcaaggggaaaactcctgaggagattcgcaagaccttcaat
atcaaaaatgactttactgaagaggaggaagcccaggtacgcaaagagaaccagtggtgt
gaagagaagtga

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