| Entry |
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| Symbol |
SLC18A1, CGAT, VAT1, VMAT1
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| Name |
(RefSeq) solute carrier family 18 member A1
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| KO |
| K08155 | MFS transporter, DHA1 family, solute carrier family 18 (vesicular amine transporter), member 1/2 |
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| Organism |
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| Pathway |
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| Network |
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| Element |
| N01040 | Transport of dopamine to synaptic vesicle |
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| Drug target |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04082 Neuroactive ligand signaling
6570 (SLC18A1)
09150 Organismal Systems
09156 Nervous system
04728 Dopaminergic synapse
6570 (SLC18A1)
04726 Serotonergic synapse
6570 (SLC18A1)
04721 Synaptic vesicle cycle
6570 (SLC18A1)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
6570 (SLC18A1)
09165 Substance dependence
05030 Cocaine addiction
6570 (SLC18A1)
05031 Amphetamine addiction
6570 (SLC18A1)
05034 Alcoholism
6570 (SLC18A1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:hsa02000]
6570 (SLC18A1)
Transporters [BR:hsa02000]
Solute carrier family (SLC)
SLC18: Vesicular amine transporter
6570 (SLC18A1)
Major facilitator superfamily (MFS)
Drug transporters
Drug:H+ antiporter-1 (12 spanner) (DHA1) family [TC:2.A.1.2]
6570 (SLC18A1)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| LinkDB |
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| Position |
8:complement(20144855..20183136)
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| AA seq |
525 aa
MLRTILDAPQRLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSS
LHLGHAGSSPHALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISA
HKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLS
TVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGL
LVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDP
YILVAAGSICFANMGVAILEPTLPIWMMQTMCSPKWQLGLAFLPASVSYLIGTNLFGVLA
NKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDL
RHTSVYGSVYAIADVAFCMGFAIGPSTGGAIVKAIGFPWLMVITGVINIVYAPLCYYLRS
PPAKEEKLAILSQDCPMETRMYATQKPTKEFPLGEDSDEEPDHEE |
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| NT seq |
1578 nt +upstreamnt +downstreamnt
atgctccggaccattctggatgctccccagcggttgctgaaggaggggagagcgtcccgg
cagctggtgctggtggtggtattcgtcgctttgctcctggacaacatgctgtttactgtg
gtggtgccaattgtgcccaccttcctatatgacatggagttcaaagaagtcaactcttct
ctgcacctcggccatgccggaagttccccacatgccctcgcctctcctgccttttccacc
atcttctccttcttcaacaacaacaccgtggctgttgaagaaagcgtacctagtggaata
gcatggatgaatgacactgccagcaccatcccacctccagccactgaagccatctcagct
cataaaaacaactgcttgcaaggcacaggtttcttggaggaagagattacccgggtcggg
gttctgtttgcttcaaaggctgtgatgcaacttctggtcaacccattcgtgggccctctc
accaacaggattggatatcatatccccatgtttgctggctttgttatcatgtttctctcc
acagttatgtttgctttttctgggacctatactctactctttgtggcccgaacccttcaa
ggcattggatcttcattttcatctgttgcaggtcttggaatgctggccagtgtctacact
gatgaccatgagagaggacgagccatgggaactgctctggggggcctggccttggggttg
ctggtgggagctccctttggaagtgtaatgtacgagtttgttgggaagtctgcacccttc
ctcatcctggccttcctggcactactggatggagcactccagctttgcatcctacagcct
tccaaagtctctcctgagagtgccaaggggactcccctctttatgcttctcaaagaccct
tacatcctggtggctgcagggtccatctgctttgccaacatgggggtggccatcctggag
cccacactgcccatctggatgatgcagaccatgtgctcccccaagtggcagctgggtcta
gctttcttgcctgccagtgtgtcctacctcattggcaccaacctctttggtgtgttggcc
aacaagatgggtcggtggctgtgttccctaatcgggatgctggtagtaggtaccagcttg
ctctgtgttcctctggctcacaatatttttggtctcattggccccaatgcagggcttggc
cttgccataggcatggtggattcttctatgatgcccatcatggggcacctggtggatcta
cgccacacctcggtgtatgggagtgtctacgccatcgctgatgtggctttttgcatgggc
tttgctataggtccatccaccggtggtgccattgtaaaggccatcggttttccctggctc
atggtcatcactggggtcatcaacatcgtctatgctccactctgctactacctgcggagc
cccccggcaaaggaagagaagcttgctattctgagtcaggactgccccatggagacccgg
atgtatgcaacccagaagcccacgaaggaatttcctctgggggaggacagtgatgaggag
cctgaccatgaggagtag |
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