KEGG   Homo sapiens (human): 6648
Entry
6648              CDS       T01001                                 
Symbol
SOD2, GC1, GClnc1, IPO-B, IPOB, MNSOD, MVCD6, Mn-SOD
Name
(RefSeq) superoxide dismutase 2
  KO
K04564  superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04068  FoxO signaling pathway
hsa04146  Peroxisome
hsa04211  Longevity regulating pathway
hsa04213  Longevity regulating pathway - multiple species
hsa05016  Huntington disease
hsa05208  Chemical carcinogenesis - reactive oxygen species
hsa05417  Lipid and atherosclerosis
Disease
H01456  Diabetic nephropathy
H02559  Microvascular complications of diabetes
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    6648 (SOD2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04146 Peroxisome
    6648 (SOD2)
 09150 Organismal Systems
  09149 Aging
   04211 Longevity regulating pathway
    6648 (SOD2)
   04213 Longevity regulating pathway - multiple species
    6648 (SOD2)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    6648 (SOD2)
  09164 Neurodegenerative disease
   05016 Huntington disease
    6648 (SOD2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    6648 (SOD2)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.15  Acting on superoxide as acceptor
   1.15.1  Acting on superoxide as acceptor (only sub-subclass identified to date)
    1.15.1.1  superoxide dismutase
     6648 (SOD2)
SSDB
Motif
Pfam: Sod_Fe_C Sod_Fe_N
Other DBs
NCBI-GeneID: 6648
NCBI-ProteinID: NP_000627
OMIM: 147460
HGNC: 11180
Ensembl: ENSG00000291237
Pharos: P04179(Tbio)
UniProt: P04179 A0A384NL29
Structure
LinkDB
Position
6:complement(159669069..159762281)
AA seq 222 aa
MLSRAVCGTSRQLAPVLGYLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVN
NLNVTEEKYQEALAKGDVTAQIALQPALKFNGGGHINHSIFWTNLSPNGGGEPKGELLEA
IKRDFGSFDKFKEKLTAASVGVQGSGWGWLGFNKERGHLQIAACPNQDPLQGTTGLIPLL
GIDVWEHAYYLQYKNVRPDYLKAIWNVINWENVTERYMACKK
NT seq 669 nt   +upstreamnt  +downstreamnt
atgttgagccgggcagtgtgcggcaccagcaggcagctggctccggttttggggtatctg
ggctccaggcagaagcacagcctccccgacctgccctacgactacggcgccctggaacct
cacatcaacgcgcagatcatgcagctgcaccacagcaagcaccacgcggcctacgtgaac
aacctgaacgtcaccgaggagaagtaccaggaggcgttggccaagggagatgttacagcc
cagatagctcttcagcctgcactgaagttcaatggtggtggtcatatcaatcatagcatt
ttctggacaaacctcagccctaacggtggtggagaacccaaaggggagttgctggaagcc
atcaaacgtgactttggttcctttgacaagtttaaggagaagctgacggctgcatctgtt
ggtgtccaaggctcaggttggggttggcttggtttcaataaggaacggggacacttacaa
attgctgcttgtccaaatcaggatccactgcaaggaacaacaggccttattccactgctg
gggattgatgtgtgggagcacgcttactaccttcagtataaaaatgtcaggcctgattat
ctaaaagctatttggaatgtaatcaactgggagaatgtaactgaaagatacatggcttgc
aaaaagtaa

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