| Entry |
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| Symbol |
TAP1, ABC17, ABCB2, APT1, D6S114E, MHC1D1, PSF-1, PSF1, RING4, TAP1*0102N, TAP1N
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| Name |
(RefSeq) transporter 1, ATP binding cassette subfamily B member
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| KO |
| K05653 | ATP-binding cassette, subfamily B (MDR/TAP), member 2 [EC:7.4.2.14] |
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| Organism |
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| Pathway |
| hsa04612 | Antigen processing and presentation |
| hsa05163 | Human cytomegalovirus infection |
| hsa05168 | Herpes simplex virus 1 infection |
| hsa05170 | Human immunodeficiency virus 1 infection |
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| Network |
nt06160 Human T-cell leukemia virus 1 (HTLV-1) nt06161 Human immunodeficiency virus 1 (HIV-1) nt06164 Kaposi sarcoma-associated herpesvirus (KSHV) nt06165 Epstein-Barr virus (EBV) nt06166 Human papillomavirus (HPV) nt06167 Human cytomegalovirus (HCMV) nt06168 Herpes simplex virus 1 (HSV-1) nt06229 MHC presentation (cancer) |
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| Element |
| N00363 | Antigen processing and presentation by MHC class I molecules |
| N00417 | HCMV US6 to antigen processing and presentation by MHC class I molecules |
| N00479 | EBV BNLF2a to antigen processing and presentation by MHC class I molecules |
| N00581 | HSV ICP47 to antigen processing and presentation by MHC class I molecules |
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| Disease |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
6890 (TAP1)
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagosome
6890 (TAP1)
09150 Organismal Systems
09151 Immune system
04612 Antigen processing and presentation
6890 (TAP1)
09160 Human Diseases
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
6890 (TAP1)
05168 Herpes simplex virus 1 infection
6890 (TAP1)
05163 Human cytomegalovirus infection
6890 (TAP1)
05169 Epstein-Barr virus infection
6890 (TAP1)
09163 Immune disease
05340 Primary immunodeficiency
6890 (TAP1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:hsa02000]
6890 (TAP1)
Enzymes [BR:hsa01000]
7. Translocases
7.4 Catalysing the translocation of amino acids and peptides
7.4.2 Linked to the hydrolysis of a nucleoside triphosphate
7.4.2.14 ABC-type antigen peptide transporter
6890 (TAP1)
Transporters [BR:hsa02000]
ABC transporters, eukaryotic type
ABCB (MDR/TAP) subfamily
ABCB2, 3, 8, 9, 10 subgroups
6890 (TAP1)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| LinkDB |
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| Position |
6:complement(32845209..32853704)
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| AA seq |
748 aa
MASSRCPAPRGCRCLPGASLAWLGTVLLLLADWVLLRTALPRIFSLLVPTALPLLRVWAV
GLSRWAVLWLGACGVLRATVGSKSENAGAQGWLAALKPLAAALGLALPGLALFRELISWG
APGSADSTRLLHWGSHPTAFVVSYAAALPAAALWHKLGSLWVPGGQGGSGNPVRRLLGCL
GSETRRLSLFLVLVVLSSLGEMAIPFFTGRLTDWILQDGSADTFTRNLTLMSILTIASAV
LEFVGDGIYNNTMGHVHSHLQGEVFGAVLRQETEFFQQNQTGNIMSRVTEDTSTLSDSLS
ENLSLFLWYLVRGLCLLGIMLWGSVSLTMVTLITLPLLFLLPKKVGKWYQLLEVQVRESL
AKSSQVAIEALSAMPTVRSFANEEGEAQKFREKLQEIKTLNQKEAVAYAVNSWTTSISGM
LLKVGILYIGGQLVTSGAVSSGNLVTFVLYQMQFTQAVEVLLSIYPRVQKAVGSSEKIFE
YLDRTPRCPPSGLLTPLHLEGLVQFQDVSFAYPNRPDVLVLQGLTFTLRPGEVTALVGPN
GSGKSTVAALLQNLYQPTGGQLLLDGKPLPQYEHRYLHRQVAAVGQEPQVFGRSLQENIA
YGLTQKPTMEEITAAAVKSGAHSFISGLPQGYDTEVDEAGSQLSGGQRQAVALARALIRK
PCVLILDDATSALDANSQLQVEQLLYESPERYSRSVLLITQHLSLVEQADHILFLEGGAI
REGGTHQQLMEKKGCYWAMVQAPADAPE |
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| NT seq |
2247 nt +upstreamnt +downstreamnt
atggctagctctaggtgtcccgctccccgcgggtgccgctgcctccccggagcttctctc
gcatggctggggacagtactgctacttctcgccgactgggtgctgctccggaccgcgctg
ccccgcatattctccctgctggtgcccaccgcgctgccactgctccgggtctgggcggtg
ggcctgagccgctgggccgtgctctggctgggggcctgcggggtcctcagggcaacggtt
ggctccaagagcgaaaacgcaggtgcccagggctggctggctgctttgaagccattagct
gcggcactgggcttggccctgccgggacttgccttgttccgagagctgatctcatgggga
gcccccgggtccgcggatagcaccaggctactgcactggggaagtcaccctaccgccttc
gttgtcagttatgcagcggcactgcccgcagcagccctgtggcacaaactcgggagcctc
tgggtgcccggcggtcagggcggctctggaaaccctgtgcgtcggcttctaggctgcctg
ggctcggagacgcgccgcctctcgctgttcctggtcctggtggtcctctcctctcttggg
gagatggccattccattctttacgggccgcctcactgactggattctacaagatggctca
gccgataccttcactcgaaacttaactctcatgtccattctcaccatagccagtgcagtg
ctggagttcgtgggtgacgggatctataacaacaccatgggccacgtgcacagccacttg
cagggagaggtgtttggggctgtcctgcgccaggagacggagtttttccaacagaaccag
acaggtaacatcatgtctcgggtaacagaggacacgtccaccctgagtgattctctgagt
gagaatctgagcttatttctgtggtacctggtgcgaggcctatgtctcttggggatcatg
ctctggggatcagtgtccctcaccatggtcaccctgatcaccctgcctctgcttttcctt
ctgcccaagaaggtgggaaaatggtaccagttgctggaagtgcaggtgcgggaatctctg
gcaaagtccagccaggtggccattgaggctctgtcggccatgcctacagttcgaagcttt
gccaacgaggagggcgaagcccagaagtttagggaaaagctgcaagaaataaagacactc
aaccagaaggaggctgtggcctatgcagtcaactcctggaccactagtatttcaggtatg
ctgctgaaagtgggaatcctctacattggtgggcagctggtgaccagtggggctgtaagc
agtgggaaccttgtcacatttgttctctaccagatgcagttcacccaggctgtggaggta
ctgctctccatctaccccagagtacagaaggctgtgggctcctcagagaaaatatttgag
tacctggaccgcacccctcgctgcccacccagtggtctgttgactcccttacacttggag
ggccttgtccagttccaagatgtctcctttgcctacccaaaccgcccagatgtcttagtg
ctacaggggctgacattcaccctacgccctggcgaggtgacggcgctggtgggacccaat
gggtctgggaagagcacagtggctgccctgctgcagaatctgtaccagcccaccggggga
cagctgctgttggatgggaagccccttccccaatatgagcaccgctacctgcacaggcag
gtggctgcagtgggacaagagccacaggtatttggaagaagtcttcaagaaaatattgcc
tatggcctgacccagaagccaactatggaggaaatcacagctgctgcagtaaagtctggg
gcccatagtttcatctctggactccctcagggctatgacacagaggtagacgaggctggg
agccagctgtcagggggtcagcgacaggcagtggcgttggcccgagcattgatccggaaa
ccgtgtgtacttatcctggatgatgccaccagtgccctggatgcaaacagccagttacag
gtggagcagctcctgtacgaaagccctgagcggtactcccgctcagtgcttctcatcacc
cagcacctcagcctggtggagcaggctgaccacatcctctttctggaaggaggcgctatc
cgggaggggggaacccaccagcagctcatggagaaaaaggggtgctactgggccatggtg
caggctcctgcagatgctccagaatga |
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