KEGG T01001: 6921

Homo sapiens (human): 6921

Entry

6921 CDS T01001

Gene name

ELOC, SIII, TCEB1

Definition

(RefSeq) elongin C

K03872

elongin-C

Organism

hsa Homo sapiens (human)

Pathway

hsa04066

HIF-1 signaling pathway

hsa04120

Ubiquitin mediated proteolysis

hsa05170

Human immunodeficiency virus 1 infection

hsa05200

Pathways in cancer

hsa05211

Renal cell carcinoma

Network

nt06225 HIF-1 signaling
nt06264 Renal cell carcinoma

Element

N00080

Loss of VHL to HIF-1 signaling pathway

N00081

Mutation-inactivated VHL to HIF-1 signaling pathway

Brite

KEGG Orthology (KO) [BR:hsa00001]
09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    6921 (ELOC)
09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    6921 (ELOC)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    6921 (ELOC)
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    6921 (ELOC)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    6921 (ELOC)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    6921 (ELOC)
   03400 DNA repair and recombination proteins [BR:hsa03400]
    6921 (ELOC)
Ubiquitin system [BR:hsa04121]
Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   ECV complex
    Adoptor protein
     6921 (ELOC)
   ECS complex
     6921 (ELOC)
DNA repair and recombination proteins [BR:hsa03400]
Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    Other NER factors
     6921 (ELOC)

SSDB

Motif

Pfam:

Skp1_POZ

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

Vega:

Pharos:

Q15369(Tbio)

UniProt:

Q15369 A0A024R7Y5

LinkDB

Structure

PDB:

4AJY 6GMR 6HR2 6GFX 1LM8 2C9W 6GMN 6I5N 6BVB 4B9K 1LQB 5NVV 5NW1 4W9F 4W9H 4W9K 5NVW 5NVX 5NW2 4W9C 4W9D 4W9J 4W9L 4BKS 6HAY 6GFZ 5NW0 6HAX 4BKT 5LLI 4W9I 3DCG 6FMJ 4AWJ 3ZUN 6GMX 2IZV 3ZKJ 4W9E 3ZTC 6I4X 6GFY 5NVZ 5T35 4W9G 1VCB 6FMK 6GMQ 3ZTD 6I5J 6FMI 4B95 3ZRF 3ZNG 5NVY 5BO4 3ZRC 6C5X 4WQO 4N9F 5N4W 6R7N 6R7F 6R7H 2MA9

Position

8q21.11

AA seq 112 aa
MDGEEKTYGGCEGPDAMYVKLISSDGHEFIVKREHALTSGTIKAMLSGPGQFAENETNEV
NFREIPSHVLSKVCMYFTYKVRYTNSSTEIPEFPIAPEIALELLMAANFLDC

NT seq 339 nt +upstreamnt +downstreamnt
atggatggagaggagaaaacctatggtggctgtgaaggacctgatgccatgtatgtcaaa
ttgatatcatctgatggccatgaatttattgtaaaaagagaacatgcattaacatcaggc
acgataaaagccatgttgagtggcccaggtcagtttgctgagaacgaaaccaatgaggtc
aattttagagagataccttcacatgtgctatcgaaagtatgcatgtattttacgtacaag
gttcgctacactaacagctccaccgagattcctgaattcccaattgcacctgaaattgca
ctggaactgctgatggctgcgaacttcttagattgttaa

DBGET integrated database retrieval system