Homo sapiens (human): 6921
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Entry
6921 CDS
T01001
Symbol
ELOC, SIII, TCEB1
Name
(RefSeq) elongin C
KO
K03872
elongin-C
Organism
hsa
Homo sapiens (human)
Pathway
hsa04066
HIF-1 signaling pathway
hsa04120
Ubiquitin mediated proteolysis
hsa05170
Human immunodeficiency virus 1 infection
hsa05200
Pathways in cancer
hsa05211
Renal cell carcinoma
Network
nt06225
HIF-1 signaling (cancer)
nt06264
Renal cell carcinoma
nt06509
DNA replication
nt06523
Epigenetic regulation by Polycomb complexes
nt06542
HIF signaling
Element
N00080
Loss of VHL to HIF-1 signaling pathway
N00081
Mutation-inactivated VHL to HIF-1 signaling pathway
N01473
DNA replication termination
N01577
Gene silencing by methylation of H3K27 and ubiquitination of H2AK119
N01872
Proteasomal degradation of HIF by VHL complex
N01873
VHL mutation to HIF-2 signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
6921 (ELOC)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
6921 (ELOC)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
6921 (ELOC)
09162 Cancer: specific types
05211 Renal cell carcinoma
6921 (ELOC)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
6921 (ELOC)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
hsa04121
]
6921 (ELOC)
03400 DNA repair and recombination proteins [BR:
hsa03400
]
6921 (ELOC)
Ubiquitin system [BR:
hsa04121
]
Ubiquitin ligases (E3)
Multi subunit type E3
Cul2 complex
Adoptor protein
6921 (ELOC)
Cul5 complex
6921 (ELOC)
DNA repair and recombination proteins [BR:
hsa03400
]
Eukaryotic type
SSBR (single strand breaks repair)
NER (nucleotide excision repair)
Other NER factors
6921 (ELOC)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Skp1_POZ
Motif
Other DBs
NCBI-GeneID:
6921
NCBI-ProteinID:
NP_001191786
OMIM:
600788
HGNC:
11617
Ensembl:
ENSG00000154582
UniProt:
Q15369
Structure
PDB
PDBj
LinkDB
All DBs
Position
8:complement(73945119..73972287)
Genome browser
AA seq
112 aa
AA seq
DB search
MDGEEKTYGGCEGPDAMYVKLISSDGHEFIVKREHALTSGTIKAMLSGPGQFAENETNEV
NFREIPSHVLSKVCMYFTYKVRYTNSSTEIPEFPIAPEIALELLMAANFLDC
NT seq
339 nt
NT seq
+upstream
nt +downstream
nt
atggatggagaggagaaaacctatggtggctgtgaaggacctgatgccatgtatgtcaaa
ttgatatcatctgatggccatgaatttattgtaaaaagagaacatgcattaacatcaggc
acgataaaagccatgttgagtggcccaggtcagtttgctgagaacgaaaccaatgaggtc
aattttagagagataccttcacatgtgctatcgaaagtatgcatgtattttacgtacaag
gttcgctacactaacagctccaccgagattcctgaattcccaattgcacctgaaattgca
ctggaactgctgatggctgcgaacttcttagattgttaa
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integrated database retrieval system