| Entry |
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| Name |
DNA replication termination
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| Definition |
CMG+PIF1 -> CMG+CRL2-LRR1 -> CMG == MCM7+Ub -> MCM7+VCP+UFD1+NPL4 |
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| Expanded |
8318+4171+4172+4173+4174+4175+4176+9837+51659+64785+84296+80119 -> 8318+4171+4172+4173+4174+4175+4176+9837+51659+64785+84296+8453+9978+6923+6921+122769 -> 8318+4171+4172+4173+4174+4175+4176+9837+51659+64785+84296 == 4176+7314 -> 4176+7415+7353+55666 |
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| Class |
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| Type |
Reference
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| Gene |
| 8318 | CDC45; cell division cycle 45 |
| 4171 | MCM2; minichromosome maintenance complex component 2 |
| 4172 | MCM3; minichromosome maintenance complex component 3 |
| 4173 | MCM4; minichromosome maintenance complex component 4 |
| 4174 | MCM5; minichromosome maintenance complex component 5 |
| 4175 | MCM6; minichromosome maintenance complex component 6 |
| 4176 | MCM7; minichromosome maintenance complex component 7 |
| 9837 | GINS1; GINS complex subunit 1 |
| 51659 | GINS2; GINS complex subunit 2 |
| 64785 | GINS3; GINS complex subunit 3 |
| 84296 | GINS4; GINS complex subunit 4 |
| 80119 | PIF1; PIF1 5'-to-3' DNA helicase |
| 122769 | LRR1; leucine rich repeat protein 1 |
| 7415 | VCP; valosin containing protein |
| 7353 | UFD1; ubiquitin recognition factor in ER associated degradation 1 |
| 55666 | NPLOC4; NPL4 homolog, ubiquitin recognition factor |
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| Reference |
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| Authors |
Moreno SP, Gambus A |
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| Title |
Mechanisms of eukaryotic replisome disassembly. |
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| Journal |
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| Reference |
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| Authors |
Villa F, Fujisawa R, Ainsworth J, Nishimura K, Lie-A-Ling M, Lacaud G, Labib KP |
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| Title |
CUL2(LRR1) , TRAIP and p97 control CMG helicase disassembly in the mammalian cell cycle. |
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| Journal |
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| Reference |
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| Authors |
Le TT, Ainsworth J, Polo Rivera C, Macartney T, Labib KPM |
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| Title |
Reconstitution of human CMG helicase ubiquitylation by CUL2LRR1 and multiple E2 enzymes. |
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| Journal |
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| LinkDB |
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