Homo sapiens (human): 7098
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Entry
7098 CDS
T01001
Symbol
TLR3, CD283, IIAE2, IMD83
Name
(RefSeq) toll like receptor 3
KO
K05401
toll-like receptor 3
Organism
hsa
Homo sapiens (human)
Pathway
hsa04217
Necroptosis
hsa04620
Toll-like receptor signaling pathway
hsa05160
Hepatitis C
hsa05161
Hepatitis B
hsa05164
Influenza A
hsa05165
Human papillomavirus infection
hsa05167
Kaposi sarcoma-associated herpesvirus infection
hsa05168
Herpes simplex virus 1 infection
hsa05171
Coronavirus disease - COVID-19
Network
nt06162
Hepatitis B virus (HBV)
nt06163
Hepatitis C virus (HCV)
nt06164
Kaposi sarcoma-associated herpesvirus (KSHV)
nt06166
Human papillomavirus (HPV)
nt06168
Herpes simplex virus 1 (HSV-1)
nt06263
Hepatocellular carcinoma
nt06517
TLR signaling
nt06527
Necroptosis
Element
N00148
TLR3-IRF7 signaling pathway
N00149
TLR3-IRF3 signaling pathway
N00563
TLR3-NFKB signaling pathway
N00564
HSV US3 to TLR3-NFKB signaling pathway
N01633
TLR3-RIPK3 signaling pathway
Disease
H01563
HIV infection
H02536
Infection-induced acute encephalopathy
Drug target
Rintatolimod:
D09661
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
7098 (TLR3)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
7098 (TLR3)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
7098 (TLR3)
05160 Hepatitis C
7098 (TLR3)
05171 Coronavirus disease - COVID-19
7098 (TLR3)
05164 Influenza A
7098 (TLR3)
05168 Herpes simplex virus 1 infection
7098 (TLR3)
05167 Kaposi sarcoma-associated herpesvirus infection
7098 (TLR3)
05165 Human papillomavirus infection
7098 (TLR3)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04054 Pattern recognition receptors [BR:
hsa04054
]
7098 (TLR3)
04090 CD molecules [BR:
hsa04090
]
7098 (TLR3)
Pattern recognition receptors [BR:
hsa04054
]
Membrane-bound pattern recognition receptors
Toll-like receptors
7098 (TLR3)
CD molecules [BR:
hsa04090
]
Proteins
7098 (TLR3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
LRR_8
LRR_4
LRR_5
LRR_1
Tlr3_TMD
LRR_9
TIR
TIR_2
LRRNT
LRRCT
Motif
Other DBs
NCBI-GeneID:
7098
NCBI-ProteinID:
NP_003256
OMIM:
603029
HGNC:
11849
Ensembl:
ENSG00000164342
UniProt:
O15455
Structure
PDB
PDBj
LinkDB
All DBs
Position
4:186069156..186088073
Genome browser
AA seq
904 aa
AA seq
DB search
MRQTLPCIYFWGGLLPFGMLCASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTH
NQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFA
FCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSN
NKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEK
LCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQL
EYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHL
NMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKIS
KIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVP
SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN
NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT
LPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNW
INETHTNIPELSSHYLCNTPPHYHGFPVRLFDTSSCKDSAPFELFFMINTSILLIFIFIV
LLIHFEGWRISFYWNVSVHRVLGFKEIDRQTEQFEYAAYIIHAYKDKDWVWEHFSSMEKE
DQSLKFCLEERDFEAGVFELEAIVNSIKRSRKIIFVITHHLLKDPLCKRFKVHHAVQQAI
EQNLDSIILVFLEEIPDYKLNHALCLRRGMFKSHCILNWPVQKERIGAFRHKLQVALGSK
NSVH
NT seq
2715 nt
NT seq
+upstream
nt +downstream
nt
atgagacagactttgccttgtatctacttttgggggggccttttgccctttgggatgctg
tgtgcatcctccaccaccaagtgcactgttagccatgaagttgctgactgcagccacctg
aagttgactcaggtacccgatgatctacccacaaacataacagtgttgaaccttacccat
aatcaactcagaagattaccagccgccaacttcacaaggtatagccagctaactagcttg
gatgtaggatttaacaccatctcaaaactggagccagaattgtgccagaaacttcccatg
ttaaaagttttgaacctccagcacaatgagctatctcaactttctgataaaacctttgcc
ttctgcacgaatttgactgaactccatctcatgtccaactcaatccagaaaattaaaaat
aatccctttgtcaagcagaagaatttaatcacattagatctgtctcataatggcttgtca
tctacaaaattaggaactcaggttcagctggaaaatctccaagagcttctattatcaaac
aataaaattcaagcgctaaaaagtgaagaactggatatctttgccaattcatctttaaaa
aaattagagttgtcatcgaatcaaattaaagagttttctccagggtgttttcacgcaatt
ggaagattatttggcctctttctgaacaatgtccagctgggtcccagccttacagagaag
ctatgtttggaattagcaaacacaagcattcggaatctgtctctgagtaacagccagctg
tccaccaccagcaatacaactttcttgggactaaagtggacaaatctcactatgctcgat
ctttcctacaacaacttaaatgtggttggtaacgattcctttgcttggcttccacaacta
gaatatttcttcctagagtataataatatacagcatttgttttctcactctttgcacggg
cttttcaatgtgaggtacctgaatttgaaacggtcttttactaaacaaagtatttccctt
gcctcactccccaagattgatgatttttcttttcagtggctaaaatgtttggagcacctt
aacatggaagataatgatattccaggcataaaaagcaatatgttcacaggattgataaac
ctgaaatacttaagtctatccaactcctttacaagtttgcgaactttgacaaatgaaaca
tttgtatcacttgctcattctcccttacacatactcaacctaaccaagaataaaatctca
aaaatagagagtgatgctttctcttggttgggccacctagaagtacttgacctgggcctt
aatgaaattgggcaagaactcacaggccaggaatggagaggtctagaaaatattttcgaa
atctatctttcctacaacaagtacctgcagctgactaggaactcctttgccttggtccca
agccttcaacgactgatgctccgaagggtggcccttaaaaatgtggatagctctccttca
ccattccagcctcttcgtaacttgaccattctggatctaagcaacaacaacatagccaac
ataaatgatgacatgttggagggtcttgagaaactagaaattctcgatttgcagcataac
aacttagcacggctctggaaacacgcaaaccctggtggtcccatttatttcctaaagggt
ctgtctcacctccacatccttaacttggagtccaacggctttgacgagatcccagttgag
gtcttcaaggatttatttgaactaaagatcatcgatttaggattgaataatttaaacaca
cttccagcatctgtctttaataatcaggtgtctctaaagtcattgaaccttcagaagaat
ctcataacatccgttgagaagaaggttttcgggccagctttcaggaacctgactgagtta
gatatgcgctttaatccctttgattgcacgtgtgaaagtattgcctggtttgttaattgg
attaacgagacccataccaacatccctgagctgtcaagccactacctttgcaacactcca
cctcactatcatgggttcccagtgagactttttgatacatcatcttgcaaagacagtgcc
ccctttgaactctttttcatgatcaataccagtatcctgttgatttttatctttattgta
cttctcatccactttgagggctggaggatatctttttattggaatgtttcagtacatcga
gttcttggtttcaaagaaatagacagacagacagaacagtttgaatatgcagcatatata
attcatgcctataaagataaggattgggtctgggaacatttctcttcaatggaaaaggaa
gaccaatctctcaaattttgtctggaagaaagggactttgaggcgggtgtttttgaacta
gaagcaattgttaacagcatcaaaagaagcagaaaaattatttttgttataacacaccat
ctattaaaagacccattatgcaaaagattcaaggtacatcatgcagttcaacaagctatt
gaacaaaatctggattccattatattggttttccttgaggagattccagattataaactg
aaccatgcactctgtttgcgaagaggaatgtttaaatctcactgcatcttgaactggcca
gttcagaaagaacggataggtgcctttcgtcataaattgcaagtagcacttggatccaaa
aactctgtacattaa
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integrated database retrieval system
