Homo sapiens (human): 7222
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Entry
7222 CDS
T01001
Gene name
TRPC3, SCA41, TRP3
Definition
(RefSeq) transient receptor potential cation channel subfamily C member 3
KO
K04966
transient receptor potential cation channel subfamily C member 3
Organism
hsa
Homo sapiens (human)
Pathway
hsa04360
Axon guidance
hsa05017
Spinocerebellar ataxia
hsa05022
Pathways of neurodegeneration - multiple diseases
Network
nt06410
Calcium signaling
nt06462
Spinocerebellar ataxia
nt06463
Parkinson disease
Element
N00953
mGluR1-TRPC3 signaling pathway
N00955
Mutation-inactivated PRKCG to mGluR1-TRPC3 signaling pathway
N00956
Mutation-activated PRKCG to mGluR1-TRPC3 signaling pathway
N00961
Mutation-activated TRPC3 to mGluR1-TRPC3 signaling pathway
Disease
H00063
Spinocerebellar ataxia (SCA)
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09158 Development and regeneration
04360 Axon guidance
7222 (TRPC3)
09160 Human Diseases
09164 Neurodegenerative disease
05017 Spinocerebellar ataxia
7222 (TRPC3)
05022 Pathways of neurodegeneration - multiple diseases
7222 (TRPC3)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
hsa04040
]
7222 (TRPC3)
Ion channels [BR:
hsa04040
]
Voltage-gated cation channels
Transient receptor potential channel (TRP)
7222 (TRPC3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ion_trans
TRP_2
PKD_channel
Ank_2
Ank_4
PBC
MCM_N
MFS_4
Motif
Other DBs
NCBI-GeneID:
7222
NCBI-ProteinID:
NP_003296
OMIM:
602345
HGNC:
12335
Ensembl:
ENSG00000138741
Vega:
OTTHUMG00000133069
Pharos:
Q13507
(Tchem)
UniProt:
Q13507
LinkDB
All DBs
Structure
PDB:
6CUD
6D7L
5ZBG
6DJS
Thumbnails
Position
4q27
AA seq
848 aa
AA seq
DB search
MEGSPSLRRMTVMREKGRRQAVRGPAFMFNDRGTSLTAEEERFLDAAEYGNIPVVRKMLE
ESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARIGDALLLAISKGYVRIVEA
ILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGTRFSPDITPIILAAHCQKYEVVHMLL
MKGARIERPHDYFCKCGDCMEKQRHDSFSHSRSRINAYKGLASPAYLSLSSEDPVLTALE
LSNELAKLANIEKEFKNDYRKLSMQCKDFVVGVLDLCRDSEEVEAILNGDLESAEPLEVH
RHKASLSRVKLAIKYEVKKFVAHPNCQQQLLTIWYENLSGLREQTIAIKCLVVLVVALGL
PFLAIGYWIAPCSRLGKILRSPFMKFVAHAASFIIFLGLLVFNASDRFEGITTLPNITVT
DYPKQIFRVKTTQFTWTEMLIMVWVLGMMWSECKELWLEGPREYILQLWNVLDFGMLSIF
IAAFTARFLAFLQATKAQQYVDSYVQESDLSEVTLPPEIQYFTYARDKWLPSDPQIISEG
LYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVLFIMVFFAFMIGMFILYS
YYLGAKVNAAFTTVEESFKTLFWSIFGLSEVTSVVLKYDHKFIENIGYVLYGIYNVTMVV
VLLNMLIAMINSSYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPPFSLVPSPKSFVYFI
MRIVNFPKCRRRRLQKDIEMGMGNSKSRLNLFTQSNSRVFESHSFNSILNQPTRYQQIMK
RLIKRYVLKAQVDKENDEVNEGELKEIKQDISSLRYELLEDKSQATEELAILIHKLSEKL
NPSMLRCE
NT seq
2547 nt
NT seq
+upstream
nt +downstream
nt
atggagggaagcccatccctgagacgcatgacagtgatgcgggagaagggccggcgccag
gctgtcaggggcccggccttcatgttcaatgaccgcggcaccagcctcaccgccgaggag
gagcgcttcctcgacgccgccgagtacggcaacatcccagtggtgcgcaagatgctggag
gagtccaagacgctgaacgtcaactgcgtggactacatgggccagaacgcgctgcagctg
gctgtgggcaacgagcacctggaggtgaccgagctgctgctcaagaaggagaacctggcg
cgcattggcgacgccctgctgctcgccatcagcaagggctacgtgcgcatcgtagaggcc
atcctcaaccaccctggcttcgcggccagcaagcgtctcactctgagcccctgtgagcag
gagctgcaggacgacgacttctacgcttacgacgaggacggcacgcgcttctcgccggac
atcacccccatcatcctggcggcgcactgccagaaatacgaagtggtgcacatgctgctg
atgaagggtgccaggatcgagcggccgcacgactatttctgcaagtgcggggactgcatg
gagaagcagaggcacgactccttcagccactcacgctcgaggatcaatgcctacaagggg
ctggccagcccggcttacctctcattgtccagcgaggacccggtgcttacggccctagag
ctcagcaacgagctggccaagctggccaacatagagaaggagttcaagaatgactatcgg
aagctctccatgcaatgcaaagactttgtagtgggtgtgctggatctctgccgagactca
gaagaggtagaagccattctgaatggagatctggaatcagcagagcctctggaggtacac
aggcacaaagcttcattaagtcgtgtcaaacttgccattaagtatgaagtcaaaaagttt
gtggctcatcccaactgccagcagcagctcttgacgatctggtatgagaacctctcaggc
ctaagggagcagaccatagctatcaagtgtctcgttgtgctggtcgtggccctgggcctt
ccattcctggccattggctactggatcgcaccttgcagcaggctggggaaaattctgcga
agcccttttatgaagtttgtagcacatgcagcttctttcatcatcttcctgggtctgctt
gtgttcaatgcctcagacaggttcgaaggcatcaccacgctgcccaatatcacagttact
gactatcccaaacagatcttcagggtgaaaaccacccagtttacatggactgaaatgcta
attatggtctgggttcttggaatgatgtggtctgaatgtaaagagctctggctggaagga
cctagggaatacattttgcagttgtggaatgtgcttgactttgggatgctgtccatcttc
attgctgctttcacagccagattcctagctttccttcaggcaacgaaggcacaacagtat
gtggacagttacgtccaagagagtgacctcagtgaagtgacactcccaccagagatacag
tatttcacttatgctagagataaatggctcccttctgaccctcagattatatctgaaggc
ctttatgccatagctgttgtgctcagcttctctcggattgcgtacatcctccctgcaaat
gagagctttggccccctgcagatctctcttggaaggactgtaaaggacatattcaagttc
atggtcctctttattatggtgttttttgcctttatgattggcatgttcatactttattct
tactaccttggggctaaagttaatgctgcttttaccactgtagaagaaagtttcaagact
ttattttggtcaatatttgggttgtctgaagtgacttccgttgtgctcaaatatgatcac
aaattcatagaaaatattggatacgttctttatggaatatacaatgtaactatggtggtc
gttttactcaacatgctaattgctatgattaatagctcatatcaagaaattgaggatgac
agtgatgtagaatggaagtttgctcgttcaaaactttggttatcctattttgatgatgga
aaaacattacctccacctttcagtctagttcctagtccaaaatcatttgtttatttcatc
atgcgaattgttaactttcccaaatgcagaaggagaaggcttcagaaggatatagaaatg
ggaatgggtaactcaaagtccaggttaaacctcttcactcagtctaactcaagagttttt
gaatcacacagttttaacagcattctcaatcagccaacacgttatcagcagataatgaaa
agacttataaagcggtatgttttgaaagcacaagtagacaaagaaaatgatgaagttaat
gaaggtgaattaaaagaaatcaagcaagatatctccagccttcgttatgaacttttggaa
gacaagagccaagcaactgaggaattagccattctaattcataaacttagtgagaaactg
aatcccagcatgctgagatgtgaatga
DBGET
integrated database retrieval system
