KEGG ORTHOLOGY: K04966

ORTHOLOGY: K04966

Entry

K04966                      KO

Symbol

TRPC3

Name

transient receptor potential cation channel subfamily C member 3

Pathway

map04360

Axon guidance

map05017

Spinocerebellar ataxia

map05022

Pathways of neurodegeneration - multiple diseases

Disease

H00063

Spinocerebellar ataxia (SCA)

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    K04966  TRPC3; transient receptor potential cation channel subfamily C member 3
09160 Human Diseases
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    K04966  TRPC3; transient receptor potential cation channel subfamily C member 3
   05022 Pathways of neurodegeneration - multiple diseases
    K04966  TRPC3; transient receptor potential cation channel subfamily C member 3
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04966  TRPC3; transient receptor potential cation channel subfamily C member 3
Ion channels [BR:ko04040]
Voltage-gated cation channels
  Transient receptor potential channel (TRP)
   K04966  TRPC3; transient receptor potential cation channel subfamily C member 3

Other DBs

GO:

0015279

TC:

1.A.4.1.4

Genes

HSA:	7222(TRPC3)

PTR:	471294(TRPC3)

PPS:	100986222(TRPC3)

GGO:	101130961(TRPC3)

PON:	100454158(TRPC3)

PPYG:

129035635(TRPC3)

NLE:	100589080(TRPC3)

HMH:	116463549(TRPC3)

SSYN:

129480661(TRPC3)

MCC:	707586(TRPC3)

MCF:	102123945(TRPC3)

MTHB:

126955739

MNI:	105486144(TRPC3)

CSAB:

103236206(TRPC3)

CATY:

105571517(TRPC3)

PANU:

100999924(TRPC3)

TGE:	112624870(TRPC3)

MLEU:

105536884(TRPC3)

RRO:	104661788(TRPC3)

RBB:	108515603(TRPC3)

TFN:	117085865(TRPC3)

PTEH:

111546232(TRPC3)

CANG:

105516412(TRPC3)

CJC:	100387575(TRPC3)

SBQ:	101054208(TRPC3)

CIMI:

108281891(TRPC3)

ANAN:

105731366(TRPC3)

CSYR:

103270884(TRPC3)

MMUR:

105882105(TRPC3)

LCAT:

123638598(TRPC3)

PCOQ:

105815261(TRPC3)

OGA:	100967113(TRPC3)

MMU:	22065(Trpc3)

MCAL:

110290880(Trpc3)

MPAH:

110319826(Trpc3)

RNO:	60395(Trpc3)

MCOC:

116095106(Trpc3)

ANU:	117707741(Trpc3)

ASYL:

127683405(Trpc3)

MUN:	110559636(Trpc3)

CGE:	100689209(Trpc3)

MAUA:

106022869(Trpc3)

PROB:

127223310(Trpc3)

PLEU:

114707171(Trpc3)

PMAV:

102919639(Trpc3)

MORG:

121453061(Trpc3)

MFOT:

126499309

AAMP:

119826609(Trpc3)

NGI:	103746954(Trpc3)

HGL:	101719053(Trpc3)

CPOC:

100135636(Trpc3)

CCAN:

109684633

DORD:

105989871(Trpc3)

DSP:	122119059(Trpc3)

DMER:

138827029(Trpc3)

PLOP:

125341440(Trpc3)

NCAR:

124994631

MMMA:

107136740(Trpc3)

ITI:	101961372(Trpc3)

OCU:

100343668

OPI:	101531686(TRPC3)

OCZ:	121146977(TRPC3)

TUP:	102477304(TRPC3)

GVR:	103603474(TRPC3)

CFA:	483844(TRPC3)

CLUD:

112642740(TRPC3)

VVP:	112933630(TRPC3)

VLG:	121493461(TRPC3)

NPO:	129504368(TRPC3)

AML:	100483524(TRPC3)

UMR:	103661799(TRPC3)

UAH:	113255631(TRPC3)

UAR:	123793117(TRPC3)

ELK:

111157236

LLV:

125093345

MPUF:

101675176(TRPC3)

MNP:	132002826(TRPC3)

MLK:	131828493(TRPC3)

NVS:	122890136(TRPC3)

ORO:	101362437(TRPC3)

EJU:	114203240 114203241 114208197(TRPC3)

ZCA:	113924237(TRPC3)

MLX:	118022476(TRPC3)

NSU:	110573038(TRPC3)

LWW:	102732298 102744643

FCA:	101087919(TRPC3)

PYU:	121030240(TRPC3)

PCOO:

112858482(TRPC3)

PBG:	122476475(TRPC3)

PVIV:

125163911(TRPC3)

LRUF:

124520921

LGF:	123593024(TRPC3)

AJU:

106977092

PTG:	102958098(TRPC3)

PPAD:

109248867(TRPC3)

PUC:

125922416

PLEZ:

122217014(TRPC3)

HHV:	120238037(TRPC3)

BTA:	286866(TRPC3)

BOM:	102273672(TRPC3)

BIU:	109571537(TRPC3)

BBUB:

102397406(TRPC3)

BBIS:

105003239(TRPC3)

CHX:	102184361(TRPC3)

OAS:	101105027(TRPC3)

BTAX:

128062366(TRPC3)

CSUM:

138093825(TRPC3)

ODA:	120870989(TRPC3)

CCAD:

122453288(TRPC3)

MREE:

136145692(TRPC3)

OVR:	110150249(TRPC3)

MBEZ:

129542690(TRPC3)

SSC:	397210(TRPC3)

CFR:	102513654(TRPC3)

CBAI:

105067118(TRPC3)

CDK:	105093661(TRPC3)

VPC:	102533891(TRPC3)

BACU:

103018728(TRPC3)

BMUS:

118895158(TRPC3)

LVE:	103072513(TRPC3)

OOR:	101273749(TRPC3)

LALB:

132519495(TRPC3)

GMF:	115857150(TRPC3)

DDP:	132425592(TRPC3)

DLE:	111186116(TRPC3)

PCAD:

102993812(TRPC3)

PSIU:

116754235(TRPC3)

PPHC:

136123811(TRPC3)

NASI:

112399754(TRPC3)

ECB:	100072204(TRPC3)

EPZ:	103567832(TRPC3)

EAI:	106834075(TRPC3)

MYB:	102251383(TRPC3)

MYD:	102758563(TRPC3)

MMYO:

118658978(TRPC3)

MLF:	102441906(TRPC3)

MDT:	132234578(TRPC3)

MYUM:

139011332(TRPC3)

PKL:	118725962(TRPC3)

EFUS:

103301646(TRPC3)

MNA:	107528422(TRPC3)

DRO:	112312407(TRPC3)

SHON:

118995490(TRPC3)

AJM:	119037639(TRPC3)

PDIC:

114503037(TRPC3)

PHAS:

123813709(TRPC3)

MMF:	118615532(TRPC3)

PPAM:

129062505(TRPC3)

HAI:	109396477(TRPC3)

RFQ:	117038351(TRPC3)

PALE:

102894586(TRPC3)

PGIG:

120616221(TRPC3)

PVP:	105302210(TRPC3)

RAY:	107521156(TRPC3)

MJV:	108400101(TRPC3)

TOD:	119233907(TRPC3)

SARA:

101554384(TRPC3)

SFUM:

130042332(TRPC3)

SETR:

126003705(TRPC3)

LAV:	100655262(TRPC3)

TMU:

101359495

ETF:	101642944(TRPC3)

DNM:	101414949(TRPC3)

MDO:	100016978(TRPC3)

GAS:	123251228(TRPC3)

SHR:	100913885(TRPC3)

AFZ:

127539805

PCW:	110223028(TRPC3)

TVP:	118853795(TRPC3)

PBRV:

138174568(TRPC3)

MLAO:

141519072(TRPC3)

OAA:	100082395(TRPC3)

TACU:

119947726(TRPC3)

GGA:	374153(TRPC3)

PCOC:

116231225(TRPC3)

MGP:	100551151(TRPC3)

CJO:	107313561(TRPC3)

TPAI:

128080261(TRPC3)

LMUT:

125692048(TRPC3)

NMEL:

110397623(TRPC3)

APLA:

101792759(TRPC3)

ACYG:

106042446(TRPC3)

CATA:

118252037(TRPC3)

AFUL:

116489102(TRPC3)

TGU:	100225813(TRPC3)

LSR:	110484345(TRPC3)

SCAN:

103821413(TRPC3)

PMOA:

120508888(TRPC3)

OTC:	121339885(TRPC3)

PRUF:

121361524(TRPC3)

ATRC:

139602565(TRPC3)

GFR:	102033175(TRPC3)

FAB:	101821058(TRPC3)

OMA:	130252447(TRPC3)

PHI:	102105456(TRPC3)

PMAJ:

107203021(TRPC3)

CCAE:

111929040(TRPC3)

CCW:	104693689(TRPC3)

CBRC:

103617445(TRPC3)

ACOE:

138109355(TRPC3)

ETL:

114067389

ZAB:	102073983(TRPC3)

ZLE:	135446984(TRPC3)

ACHL:

103808190(TRPC3)

SVG:	106859402(TRPC3)

MMEA:

130582079(TRPC3)

HRT:	120753429(TRPC3)

SATI:

136360717(TRPC3)

CFAI:

136291523(TRPC3)

CCIC:

134044098(TRPC3)

FPG:	101917699(TRPC3)

FCH:	102053966(TRPC3)

CCRI:

104161341(TRPC3)

NNT:	104406382(TRPC3)

SHAB:

115605221(TRPC3)

ACUN:

113479520(TRPC3)

SURA:

141942959(TRPC3)

TALA:

104365990(TRPC3)

ACHC:

115344550(TRPC3)

HALD:

104325910(TRPC3)

HLE:	104836819(TRPC3)

AGEN:

126044865

HHAR:

128154155(TRPC3)

GCL:

CSTI:

LDI:

MNB:

DPUB:

104296215(TRPC3)

PPUS:

135178738(TRPC3)

AVIT:

104274658

BRHI:

104501946(TRPC3)

EGZ:	104129312(TRPC3)

NNI:	104019123(TRPC3)

PCRI:

104025488

PCAO:

104044498

PADL:

103926111(TRPC3)

AFOR:

103907345(TRPC3)

FGA:	104073250(TRPC3)

CBOR:

142082243(TRPC3)

GSTE:

104253571

CBOY:

140651759(TRPC3)

MAME:

142409502(TRPC3)

CLV:	102094377(TRPC3)

CNIC:

135988166(TRPC3)

MUI:

104547247

PGUU:

104459645

EHS:	104516241(TRPC3)

CMAC:

104476904(TRPC3)

CUCA:

104065747(TRPC3)

TEO:	104380759(TRPC3)

BREG:

104630543(TRPC3)

GAME:

129206259(TRPC3)

OHA:	104331325(TRPC3)

ACAR:

104532909(TRPC3)

CVF:	104288986(TRPC3)

RTD:	128910045(TRPC3)

CRID:

134516017(TRPC3)

LMIC:

141743999(TRPC3)

AAM:	106492040(TRPC3)

AROW:

112973507(TRPC3)

NPD:	112950230(TRPC3)

TGT:	104578066(TRPC3)

DNE:	112980910(TRPC3)

SCAM:

104144044(TRPC3)

ASN:	102384477(TRPC3)

AMJ:	102565842(TRPC3)

CPOO:

109309329(TRPC3)

GGN:	109301138(TRPC3)

PSS:	102459570(TRPC3)

CIZ:	142012122(TRPC3)

CMY:	102947216(TRPC3)

CCAY:

125635591(TRPC3)

DCC:	119854609(TRPC3)

CPIC:

101940902(TRPC3)

TST:	117878476(TRPC3)

CABI:

116822278(TRPC3)

MRV:	120407175(TRPC3)

ACS:	100559665(trpc3)

ASAO:

132776877(TRPC3)

PVT:	110072822(TRPC3)

SUND:

121932317(TRPC3)

PBI:	103066323(TRPC3)

PMUR:

107296604(TRPC3)

CTIG:

120297482(TRPC3)

TSR:	106549540(TRPC3)

PGUT:

117680173(TRPC3)

PCAE:

139320221(TRPC3)

APRI:

131202943(TRPC3)

PTEX:

113434689(TRPC3)

NSS:	113411804(TRPC3)

VKO:	123022811(TRPC3)

PMUA:

114590060 114604125(TRPC3)

PRAF:

128421143(TRPC3)

ZVI:	118083989(TRPC3)

HCG:	128327925(TRPC3)

GJA:	107115397(TRPC3)

STOW:

125439625(TRPC3)

EMC:	129336782(TRPC3)

XLA:	108704396(trpc3.S) 108719617

XTR:	100490905(trpc3)

NPR:	108793716(TRPC3)

RTEM:

120918683(TRPC3)

ACAT:

141111313(TRPC3)

PADS:

140326830(TRPC3)

BBUF:

120989943(TRPC3)

BGAR:

122943932(TRPC3)

DTC:	141086191(TRPC3)

PWL:	138302178(TRPC3)

MUO:	115461732(TRPC3)

GSH:	117357687(TRPC3)

DRE:	101887082(trpc3)

SRX:	107715162 107757418

SANH:

107676160 107678610

SGH:	107556836 107571245

CCAR:

109074019 109098562(trpc3)

CAUA:

113047822 113080254 113113796

CGIB:

127971908 128027705

PTET:

122358127(trpc3)

LROH:

127175783(trpc3)

GRF:	141287983(trpc3)

OMC:	131553099(trpc3)

PPRM:

120465395(trpc3)

MAMB:

125261120(trpc3)

CIDE:

127494863

CERY:

137019027(trpc3)

MASI:

127413306 127418142

TROS:

130564077(trpc3)

TDW:	130437845(trpc3)

MANU:

129422111(trpc3)

PDAB:

135760289(trpc3)

IPU:	108274508(trpc3)

IFU:	128618267(trpc3)

PHYP:

113530043

SMEO:

124391900(trpc3)

TFD:	113654864(trpc3)

TVC:	132856898(trpc3)

CGAR:

128509643(trpc3)

NGRA:

132882060(trpc3)

TRN:	134319390(trpc3)

AMEX:

103037748(trpc3)

CMAO:

118812162(trpc3)

EEE:

113588606

CHAR:

105893669(trpc3)

SPIL:

134095534(trpc3)

ASAD:

121681428(trpc3)

SASA:

106604551(trpc3) 106611533

STRU:

115170166(trpc3) 115205082

OTW:	112221078(trpc3) 112257103

OMY:	110488958 110505159

OGO:	123994127(trpc3) 124011211

ONE:	115129947 115130841

OKI:	109865065 109906034

OKE:	118363616 118380059

OMM:	135526525(trpc3) 135546013

OCLA:

139366020 139390737

SALP:

111965856(trpc3) 111967605

SNH:	120046953 120061864

SFON:

129827997 129858226(trpc3)

CCLU:

121535236 121540470

ELS:

105006794

OEP:	134032541(trpc3)

SFM:	108938720(trpc3)

PKI:	111832814 111835538

AANG:

118226797 118232505

AROT:

135254557(trpc3)

CCOG:

133130765 133135016

LOC:	102692537(trpc3)

PSPA:

121323740 121329010

ARUT:

117408818 117420887

PSEX:

120527629(trpc3)

LCM:	102363699(TRPC3)

CMK:

RTP:

CPLA:

CPUN:

HOC:

SCAU:

STOZ:

LERI:

HAKA:

BFO:	118418623 118419520

BBEL:

LPIC:

LVG:

ARUN:

AAMU:

AFIL:

140137873 140150869 140152028 140164934 140166309

PFLL:

DALB:

RSAN:

PCAN:

BGT:

HRF:

CRG:

CANU:

CVN:

OED:

MYI:	110441447 110453393

PMAX:

AIRR:

YBA:

DPOL:

LAK:

EGL:

ATEN:

ADF:

Reference

PMID:9417057

Authors

Zhu X, Jiang M, Birnbaumer L

Title

Receptor-activated Ca2+ influx via human Trp3 stably expressed in human embryonic kidney (HEK)293 cells. Evidence for a non-capacitative Ca2+ entry.

Journal

J Biol Chem 273:133-42 (1998)
DOI:10.1074/jbc.273.1.133

Sequence

[hsa:7222]

Reference

PMID:8646775

Authors

Zhu X, Jiang M, Peyton M, Boulay G, Hurst R, Stefani E, Birnbaumer L

Title

trp, a novel mammalian gene family essential for agonist-activated capacitative Ca2+ entry.

Journal

Cell 85:661-71 (1996)
DOI:10.1016/s0092-8674(00)81233-7

Sequence

[hsa:7222]

LinkDB

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