Homo sapiens (human): 7423
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Entry
7423 CDS
T01001
Symbol
VEGFB, VEGFL, VRF
Name
(RefSeq) vascular endothelial growth factor B isoform VEGFB-186 precursor
KO
K16858
vascular endothelial growth factor B
Organism
hsa
Homo sapiens (human)
Pathway
hsa04010
MAPK signaling pathway
hsa04014
Ras signaling pathway
hsa04015
Rap1 signaling pathway
hsa04020
Calcium signaling pathway
hsa04151
PI3K-Akt signaling pathway
hsa04510
Focal adhesion
hsa04518
Integrin signaling
hsa04926
Relaxin signaling pathway
hsa04933
AGE-RAGE signaling pathway in diabetic complications
hsa05200
Pathways in cancer
Network
nt06526
MAPK signaling
nt06528
Calcium signaling
nt06530
PI3K signaling
Element
N01592
GF-RTK-RAS-ERK signaling pathway
N01641
RTK-PLCG-ITPR signaling pathway
N01656
GF-RTK-PI3K signaling pathway
N01658
GF-RTK-RAS-PI3K signaling pathway
Drug target
Aflibercept:
D09574
<JP/US>
Aflibercept beta:
D10819
<JP>
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
7423 (VEGFB)
04014 Ras signaling pathway
7423 (VEGFB)
04015 Rap1 signaling pathway
7423 (VEGFB)
04020 Calcium signaling pathway
7423 (VEGFB)
04151 PI3K-Akt signaling pathway
7423 (VEGFB)
09133 Signaling molecules and interaction
04518 Integrin signaling
7423 (VEGFB)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
7423 (VEGFB)
09150 Organismal Systems
09152 Endocrine system
04926 Relaxin signaling pathway
7423 (VEGFB)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
7423 (VEGFB)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
7423 (VEGFB)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04052 Cytokines and neuropeptides [BR:
hsa04052
]
7423 (VEGFB)
Cytokines and neuropeptides [BR:
hsa04052
]
Cytokines
Growth factors (RTK binding)
7423 (VEGFB)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDGF
Motif
Other DBs
NCBI-GeneID:
7423
NCBI-ProteinID:
NP_003368
OMIM:
601398
HGNC:
12681
Ensembl:
ENSP00000311127.2
UniProt:
P49765
Q7LAP4
Structure
PDB
PDBj
LinkDB
All DBs
Position
11:64234584..64239264
Genome browser
AA seq
207 aa
AA seq
DB search
MSPLLRRLLLAALLQLAPAQAPVSQPDAPGHQRKVVSWIDVYTRATCQPREVVVPLTVEL
MGTVAKQLVPSCVTVQRCGGCCPDDGLECVPTGQHQVRMQILMIRYPSSQLGEMSLEEHS
QCECRPKKKDSAVKPDRAATPHHRPQPRSVPGWDSAPGAPSPADITHPTPAPGPSAHAAP
STTSALTPGPAAAAADAAASSVAKGGA
NT seq
624 nt
NT seq
+upstream
nt +downstream
nt
atgagccctctgctccgccgcctgctgctcgccgcactcctgcagctggcccccgcccag
gcccctgtctcccagcctgatgcccctggccaccagaggaaagtggtgtcatggatagat
gtgtatactcgcgctacctgccagccccgggaggtggtggtgcccttgactgtggagctc
atgggcaccgtggccaaacagctggtgcccagctgcgtgactgtgcagcgctgtggtggc
tgctgccctgacgatggcctggagtgtgtgcccactgggcagcaccaagtccggatgcag
atcctcatgatccggtacccgagcagtcagctgggggagatgtccctggaagaacacagc
cagtgtgaatgcagacctaaaaaaaaggacagtgctgtgaagccagacagggctgccact
ccccaccaccgtccccagccccgttctgttccgggctgggactctgcccccggagcaccc
tccccagctgacatcacccatcccactccagccccaggcccctctgcccacgctgcaccc
agcaccaccagcgccctgacccccggacctgccgctgccgctgccgacgccgcagcttcc
tccgttgccaagggcggggcttag
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