KEGG   Homo sapiens (human): 7520
Entry
7520              CDS       T01001                                 
Symbol
XRCC5, KARP-1, KARP1, KU80, KUB2, Ku86, NFIV
Name
(RefSeq) X-ray repair cross complementing 5
  KO
K10885  ATP-dependent DNA helicase 2 subunit 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa03450  Non-homologous end-joining
Network
nt06506  Double-strand break repair
  Element
N01445  Non-homologous end-joining
N01467  V(D)J recombination
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03450 Non-homologous end-joining
    7520 (XRCC5)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:hsa03400]
    7520 (XRCC5)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    DNA-PK complex
     7520 (XRCC5)
SSDB
Motif
Pfam: Ku_N Ku Ku_PK_bind Ku_C Beta-TrCP_D
Other DBs
NCBI-GeneID: 7520
NCBI-ProteinID: NP_066964
OMIM: 194364
HGNC: 12833
Ensembl: ENSG00000079246
Pharos: P13010(Tbio)
UniProt: P13010
Structure
LinkDB
Position
2:216109348..216206293
AA seq 732 aa
MVRSGNKAAVVLCMDVGFTMSNSIPGIESPFEQAKKVITMFVQRQVFAENKDEIALVLFG
TDGTDNPLSGGDQYQNITVHRHLMLPDFDLLEDIESKIQPGSQQADFLDALIVSMDVIQH
ETIGKKFEKRHIEIFTDLSSRFSKSQLDIIIHSLKKCDISLQFFLPFSLGKEDGSGDRGD
GPFRLGGHGPSFPLKGITEQQKEGLEIVKMVMISLEGEDGLDEIYSFSESLRKLCVFKKI
ERHSIHWPCRLTIGSNLSIRIAAYKSILQERVKKTWTVVDAKTLKKEDIQKETVYCLNDD
DETEVLKEDIIQGFRYGSDIVPFSKVDEEQMKYKSEGKCFSVLGFCKSSQVQRRFFMGNQ
VLKVFAARDDEAAAVALSSLIHALDDLDMVAIVRYAYDKRANPQVGVAFPHIKHNYECLV
YVQLPFMEDLRQYMFSSLKNSKKYAPTEAQLNAVDALIDSMSLAKKDEKTDTLEDLFPTT
KIPNPRFQRLFQCLLHRALHPREPLPPIQQHIWNMLNPPAEVTTKSQIPLSKIKTLFPLI
EAKKKDQVTAQEIFQDNHEDGPTAKKLKTEQGGAHFSVSSLAEGSVTSVGSVNPAENFRV
LVKQKKASFEEASNQLINHIEQFLDTNETPYFMKSIDCIRAFREEAIKFSEEQRFNNFLK
ALQEKVEIKQLNHFWEIVVQDGITLITKEEASGSSVTAEEAKKFLAPKDKPSGDTAAVFE
EGGDVDDLLDMI
NT seq 2199 nt   +upstreamnt  +downstreamnt
atggtgcggtcggggaataaggcagctgttgtgctgtgtatggacgtgggctttaccatg
agtaactccattcctggtatagaatccccatttgaacaagcaaagaaggtgataaccatg
tttgtacagcgacaggtgtttgctgagaacaaggatgagattgctttagtcctgtttggt
acagatggcactgacaatcccctttctggtggggatcagtatcagaacatcacagtgcac
agacatctgatgctaccagattttgatttgctggaggacattgaaagcaaaatccaacca
ggttctcaacaggctgacttcctggatgcactaatcgtgagcatggatgtgattcaacat
gaaacaataggaaagaagtttgagaagaggcatattgaaatattcactgacctcagcagc
cgattcagcaaaagtcagctggatattataattcatagcttgaagaaatgtgacatctcc
ctgcaattcttcttgcctttctcacttggcaaggaagatggaagtggggacagaggagat
ggcccctttcgcttaggtggccatgggccttcctttccactaaaaggaattaccgaacag
caaaaagaaggtcttgagatagtgaaaatggtgatgatatctttagaaggtgaagatggg
ttggatgaaatttattcattcagtgagagtctgagaaaactgtgcgtcttcaagaaaatt
gagaggcattccattcactggccctgccgactgaccattggctccaatttgtctataagg
attgcagcctataaatcgattctacaggagagagttaaaaagacttggacagttgtggat
gcaaaaaccctaaaaaaagaagatatacaaaaagaaacagtttattgcttaaatgatgat
gatgaaactgaagttttaaaagaggatattattcaagggttccgctatggaagtgatata
gttcctttctctaaagtggatgaggaacaaatgaaatataaatcggaggggaagtgcttc
tctgttttgggattttgtaaatcttctcaggttcagagaagattcttcatgggaaatcaa
gttctaaaggtctttgcagcaagagatgatgaggcagctgcagttgcactttcctccctg
attcatgctttggatgacttagacatggtggccatagttcgatatgcttatgacaaaaga
gctaatcctcaagtcggcgtggcttttcctcatatcaagcataactatgagtgtttagtg
tatgtgcagctgcctttcatggaagacttgcggcaatacatgttttcatccttgaaaaac
agtaagaaatatgctcccaccgaggcacagttgaatgctgttgatgctttgattgactcc
atgagcttggcaaagaaagatgagaagacagacacccttgaagacttgtttccaaccacc
aaaatcccaaatcctcgatttcagagattatttcagtgtctgctgcacagagctttacat
ccccgggagcctctacccccaattcagcagcatatttggaatatgctgaatcctcccgct
gaggtgacaacaaaaagtcagattcctctctctaaaataaagaccctttttcctctgatt
gaagccaagaaaaaggatcaagtgactgctcaggaaattttccaagacaaccatgaagat
ggacctacagctaaaaaattaaagactgagcaagggggagcccacttcagcgtctccagt
ctggctgaaggcagtgtcacctctgttggaagtgtgaatcctgctgaaaacttccgtgtt
ctagtgaaacagaagaaggccagctttgaggaagcgagtaaccagctcataaatcacatc
gaacagtttttggatactaatgaaacaccgtattttatgaagagcatagactgcatccga
gccttccgggaagaagccattaagttttcagaagagcagcgctttaacaacttcctgaaa
gcccttcaagagaaagtggaaattaaacaattaaatcatttctgggaaattgttgtccag
gatggaattactctgatcaccaaagaggaagcctctggaagttctgtcacagctgaggaa
gccaaaaagtttctggcccccaaagacaaaccaagtggagacacagcagctgtatttgaa
gaaggtggtgatgtggacgatttattggacatgatatag

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