KEGG T01001: 7709

Homo sapiens (human): 7709

Entry

7709 CDS T01001

Gene name

ZBTB17, MIZ-1, ZNF151, ZNF60, pHZ-67

Definition

(RefSeq) zinc finger and BTB domain containing 17

K10500

zinc finger and BTB domain-containing protein 17

Organism

hsa Homo sapiens (human)

Pathway

hsa04110

Cell cycle

hsa05200

Pathways in cancer

hsa05202

Transcriptional misregulation in cancer

hsa05222

Small cell lung cancer

Network

nt06130  Cell cycle (viruses)
nt06160  Human T-cell leukemia virus 1 (HTLV-1)
nt06230  Cell cycle G1/S
nt06240  Transcription
nt06267  Small cell lung cancer

Element

N00088

Amplified MYC to p15-cell cycle G1/S

N00090

p15-Cell cycle G1/S

N00132

Amplified MYCN to transcriptional repression

Brite

KEGG Orthology (KO) [BR:hsa00001]
09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    7709 (ZBTB17)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    7709 (ZBTB17)
   05202 Transcriptional misregulation in cancer
    7709 (ZBTB17)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    7709 (ZBTB17)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    7709 (ZBTB17)
   04121 Ubiquitin system [BR:hsa04121]
    7709 (ZBTB17)
Transcription factors [BR:hsa03000]
Eukaryotic type
  Zinc finger
   Cys2His2 BTB-ZF factors
    7709 (ZBTB17)
Ubiquitin system [BR:hsa04121]
Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   Cul3 complex
    Adoptor and target recognizing subunit (BTB)
     7709 (ZBTB17)

SSDB

Motif

Pfam:

zf-H2C2_2 zf-C2H2 zf-C2H2_4 BTB zf-C2H2_jaz zf-C2H2_11 zf-met zf-H2C2_5 zf-C2H2_6 zinc_ribbon_15 Zn-ribbon_8 zf-C2HC_2 zf-BED zf_UBZ zf-C2HE zf-Di19 Packaging_FI XPA_N HypA DUF3268

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

Vega:

Pharos:

Q13105(Tbio)

UniProt:

Q13105

LinkDB

Structure

PDB:

2Q81 3M52 5ION 2N25 2N26 2M0D 2M0E 2M0F 2LVT 2LVU 2LVR

Position

1p36.13

AA seq 803 aa
MDFPQHSQHVLEQLNQQRQLGLLCDCTFVVDGVHFKAHKAVLAACSEYFKMLFVDQKDVV
HLDISNAAGLGQVLEFMYTAKLSLSPENVDDVLAVATFLQMQDIITACHALKSLAEPATS
PGGNAEALATEGGDKRAKEEKVATSTLSRLEQAGRSTPIGPSRDLKEERGGQAQSAASGA
EQTEKADAPREPPPVELKPDPTSGMAAAEAEAALSESSEQEMEVEPARKGEEEQKEQEEQ
EEEGAGPAEVKEEGSQLENGEAPEENENEESAGTDSGQELGSEARGLRSGTYGDRTESKA
YGSVIHKCEDCGKEFTHTGNFKRHIRIHTGEKPFSCRECSKAFSDPAACKAHEKTHSPLK
PYGCEECGKSYRLISLLNLHKKRHSGEARYRCEDCGKLFTTSGNLKRHQLVHSGEKPYQC
DYCGRSFSDPTSKMRHLETHDTDKEHKCPHCDKKFNQVGNLKAHLKIHIADGPLKCRECG
KQFTTSGNLKRHLRIHSGEKPYVCIHCQRQFADPGALQRHVRIHTGEKPCQCVMCGKAFT
QASSLIAHVRQHTGEKPYVCERCGKRFVQSSQLANHIRHHDNIRPHKCSVCSKAFVNVGD
LSKHIIIHTGEKPYLCDKCGRGFNRVDNLRSHVKTVHQGKAGIKILEPEEGSEVSVVTVD
DMVTLATEALAATAVTQLTVVPVGAAVTADETEVLKAEISKAVKQVQEEDPNTHILYACD
SCGDKFLDANSLAQHVRIHTAQALVMFQTDADFYQQYGPGGTWPAGQVLQAGELVFRPRD
GAEGQPALAETSPTAPECPPPAE

NT seq 2412 nt +upstreamnt +downstreamnt
atggactttccccagcacagccagcatgtcttggaacagctgaaccagcagcggcagctg
gggcttctctgtgactgcacctttgtggtggacggtgttcactttaaggctcataaagca
gtgctggcggcctgcagcgagtacttcaagatgctcttcgtggaccagaaggacgtggtg
cacctggacatcagtaacgcggcaggcctggggcaggtgctggagtttatgtacacggcc
aagctgagcctgagccctgagaacgtggatgatgtgctggccgtggccactttcctccaa
atgcaggacatcatcacggcctgccatgccctcaagtcacttgctgagccggctaccagc
cctgggggaaatgcggaggccttggccacagaaggaggggacaagagagccaaagaggag
aaggtggccaccagcacgctgagcaggctggagcaggcaggacgcagcacacccataggc
cccagcagggacctcaaggaggagcgcggcggtcaggcccagagtgcggccagcggtgca
gagcagacagagaaagccgatgcgccccgggagccgccgcctgtggagctcaagccagac
cccacgagtggcatggctgctgcagaagctgaggccgctttgtccgagagctcggagcaa
gaaatggaggtggagcccgcccggaaaggggaagaggagcaaaaggagcaagaggagcaa
gaggaggagggcgcagggccagctgaggtcaaggaggagggttcccagctggagaacgga
gaggcccccgaggagaacgagaatgaggagtcagcgggcacagactcggggcaggagctc
ggctccgaggcccggggcctgcgctcaggcacctacggcgaccgcacggagtccaaggcc
tacggctccgtcatccacaagtgcgaggactgtgggaaggagttcacgcacacggggaac
ttcaagcggcacatccgcatccacacgggggagaagcccttctcgtgccgggagtgcagc
aaggccttttccgacccggccgcgtgcaaggcccatgagaagacgcacagccctctgaag
ccctacggctgcgaggagtgcgggaagagctaccgcctcatcagcctgctgaacctgcac
aagaagcggcactcgggcgaggcgcgctaccgctgcgaggactgcggcaagctcttcacc
acctcgggcaacctcaagcgccaccagctggtgcacagcggcgagaagccctaccagtgc
gactactgcggccgctccttctccgaccccacttccaagatgcgccacctggagacccac
gacacggacaaggagcacaagtgcccacactgcgacaagaagttcaaccaggtagggaac
ctgaaggcccacctgaagatccacatcgctgacgggcccctcaagtgccgagagtgtggg
aagcagttcaccacctcagggaacctgaagcggcaccttcggatccacagcggggagaag
ccctacgtgtgcatccactgccagcgacagtttgcagaccccggcgctctgcagcggcac
gtccgcattcacacaggtgagaagccatgccagtgtgtgatgtgcggtaaggccttcacc
caggccagctccctcatcgcccacgtgcgccagcacaccggggagaagccctacgtctgc
gagcgctgcggcaagagattcgtccagtccagccagttggccaatcatattcgccaccac
gacaacatccgcccacacaagtgcagcgtgtgcagcaaggccttcgtgaacgtgggggac
ctgtccaagcacatcatcattcacactggagagaagccttacctgtgtgataagtgtggg
cgtggcttcaaccgggtagacaacctgcgctcccacgtgaagaccgtgcaccagggcaag
gcaggcatcaagatcctggagcccgaggagggcagtgaggtcagcgtggtcactgtggat
gacatggtcacgctggctaccgaggcactggcagcgacagccgtcactcagctcacagtg
gtgccggtgggagctgcagtgacagccgatgagacggaagtcctgaaggccgagatcagc
aaagctgtgaagcaagtgcaggaagaagaccccaacactcacatcctctacgcctgtgac
tcctgtggggacaagtttctggatgccaacagcctggctcagcatgtgcgaatccacaca
gcccaggcactggtcatgttccagacagacgcggacttctatcagcagtatgggccaggt
ggcacgtggcctgccgggcaggtgctgcaggctggggagctggtcttccgccctcgcgac
ggggctgagggccagcccgcactggcagagacctcccctacagctcctgaatgtcccccg
cctgccgagtga

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