Homo sapiens (human): 79840
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Entry
79840 CDS
T01001
Symbol
NHEJ1, IMD124, XLF
Name
(RefSeq) non-homologous end joining factor 1
KO
K10980
non-homologous end-joining factor 1
Organism
hsa
Homo sapiens (human)
Pathway
hsa03450
Non-homologous end-joining
Network
nt06506
Double-strand break repair
Element
N01445
Non-homologous end-joining
N01467
V(D)J recombination
Disease
H00924
Severe combined immunodeficiency with microcephaly, growth retardation, and sensitivity to ionizing radiation
H01027
Microphthalmia
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09124 Replication and repair
03450 Non-homologous end-joining
79840 (NHEJ1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03400 DNA repair and recombination proteins [BR:
hsa03400
]
79840 (NHEJ1)
DNA repair and recombination proteins [BR:
hsa03400
]
Eukaryotic type
DSBR (double strand breaks repair)
NHEJ (non-homologous end-joining)
DNA Ligase 4 complex
79840 (NHEJ1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
XLF
XLF_CC
XRCC4
Motif
Other DBs
NCBI-GeneID:
79840
NCBI-ProteinID:
NP_079058
OMIM:
611290
HGNC:
25737
Ensembl:
ENSG00000187736
Pharos:
Q9H9Q4
(Tbio)
UniProt:
Q9H9Q4
Structure
PDB
PDBj
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All DBs
Position
2:complement(219069357..219160815)
Genome browser
AA seq
299 aa
AA seq
DB search
MEELEQGLLMQPWAWLQLAENSLLAKVFITKQGYALLVSDLQQVWHEQVDTSVVSQRAKE
LNKRLTAPPAAFLCHLDNLLRPLLKDAAHPSEATFSCDCVADALILRVRSELSGLPFYWN
FHCMLASPSLVSQHLIRPLMGMSLALQCQVRELATLLHMKDLEIQDYQESGATLIRDRLK
TEPFEENSFLEQFMIEKLPEACSIGDGKPFVMNLQDLYMAVTTQEVQVGQKHQGAGDPHT
SNSASLQGIDSQCVNQPEQLVSSAPTLSAPEKESTGTSGPLQRPQLSKVKRKKPRGLFS
NT seq
900 nt
NT seq
+upstream
nt +downstream
nt
atggaagaactggagcaaggcctgttgatgcagccatgggcgtggctacagcttgcagag
aactccctcttggccaaggtttttatcaccaagcagggctatgccttgttggtttcagat
cttcaacaggtgtggcatgaacaggtggacactagtgtggtcagccagcgagccaaggag
ctgaacaagcggctcactgctcctcctgcagctttcctctgtcatttggataatctcctt
cgcccattgttgaaggacgctgctcaccctagcgaagctaccttctcctgtgattgtgtg
gcagatgcactgattctacgggtgcgaagtgagctctctggcctccccttctattggaat
ttccactgcatgctagctagtccttccctggtctcccaacatttgattcgtcctctgatg
ggcatgagtctggcattacagtgccaagtgagggagctagcaacgttacttcatatgaaa
gacctagagatccaagactaccaggagagtggggctacgctgattcgagatcgattgaag
acagaaccatttgaagaaaattccttcttggaacaatttatgatagagaaactgccagag
gcatgcagcattggtgatggaaagccctttgtcatgaatctgcaggatctgtatatggca
gtcaccacacaagaggtccaagtgggacagaagcatcaaggcgctggagatcctcatacc
tcaaacagtgcttccctgcaaggaatcgatagccaatgtgtaaaccagccagaacaactg
gtctcctcagccccaaccctctcagcacctgagaaagagtccacgggtacttcaggccct
ctgcagagacctcagctgtcaaaggtcaagaggaagaagccaaggggtctcttcagttaa
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integrated database retrieval system
